FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382932015> ?p ?o ?g. }

• W4382932015 abstract "Sickle cell disease (SCD) poses an increased risk of infertility, pregnancy complications and maternal and perinatal mortality among women of reproductive age. This risk is particularly higher for women in sub-Saharan Africa, where the disease burden is highest and access to comprehensive health care is limited, as well as in other countries with a high SCD prevalence due to migration. Disease-modifying treatments for SCD could directly and indirectly harm the ovaries, potentially compromising the quality and quantity of existing oocytes. Therefore, it is essential to explore alternative interventions, such as nutritional modifications that are less harmful and cost-effective in order to improve reproductive outcomes and enhance the overall well-being of both mother and child in this population. Maintaining optimal levels of B12 may possibly provide benefits to the ovaries and pregnancy by decreasing homocysteine levels, increasing nitric oxide (NO) bioavailability and promoting antioxidant and anti-inflammatory activities. Individuals living with SCD are more susceptible to vitamin B12 (B12) deficiency. However, there is a lack of clinical data investigating the relationship between systemic levels of B12, its supplementation, and reproductive outcome measures in SCD women. Therefore, this review aims to examine the current evidence regarding the impact of SCD on female reproductive health and the role of B12 in the reproductive biology of women living with SCD. Lay summary Poor reproductive health is a concern for patients with sickle cell disease (SCD). SCD can lead to damage to the ovaries. Most of the therapies for sickle cell disease are toxic to the ovaries, expensive and unavailable to affected women, particularly those living in resource-poor areas such as sub-Saharan Africa. There is a need to seek less harmful and affordable interventions such as nutrition to improve reproductive outcomes for women with SCD who are of child-bearing age. Good levels of vitamin B12 have been found to maintain ovarian health and pregnancy. Patients with SCD have been reported to have a high risk of vitamin B12 deficiency, but the impact of B12 on reproduction in this group of women is yet to be evaluated. The review explores current evidence of the impact of both SCD and B12 on female reproduction." @default.
• W4382932015 created "2023-07-04" @default.
• W4382932015 creator A5011279938 @default.
• W4382932015 creator A5037763463 @default.
• W4382932015 creator A5069733342 @default.
• W4382932015 date "2023-07-01" @default.
• W4382932015 modified "2023-10-17" @default.
• W4382932015 title "Impact of vitamin B12 on the reproductive health of women with sickle cell disease: a narrative review" @default.
• W4382932015 cites W129455378 @default.
• W4382932015 cites W1757562139 @default.
• W4382932015 cites W1763433851 @default.
• W4382932015 cites W1971171680 @default.
• W4382932015 cites W1979608070 @default.
• W4382932015 cites W1988702412 @default.
• W4382932015 cites W2003999586 @default.
• W4382932015 cites W2009238481 @default.
• W4382932015 cites W2024400317 @default.
• W4382932015 cites W2040389549 @default.
• W4382932015 cites W2046831466 @default.
• W4382932015 cites W2079616793 @default.
• W4382932015 cites W2107818859 @default.
• W4382932015 cites W2109474968 @default.
• W4382932015 cites W2122867725 @default.
• W4382932015 cites W2127530512 @default.
• W4382932015 cites W2131073535 @default.
• W4382932015 cites W2144277042 @default.
• W4382932015 cites W2164168094 @default.
• W4382932015 cites W2216795828 @default.
• W4382932015 cites W2294422638 @default.
• W4382932015 cites W2325817714 @default.
• W4382932015 cites W2336946162 @default.
• W4382932015 cites W2343452117 @default.
• W4382932015 cites W2418859793 @default.
• W4382932015 cites W2490064445 @default.
• W4382932015 cites W2513621308 @default.
• W4382932015 cites W2571053339 @default.
• W4382932015 cites W2640267936 @default.
• W4382932015 cites W2676161360 @default.
• W4382932015 cites W2755972026 @default.
• W4382932015 cites W2762666897 @default.
• W4382932015 cites W2774352325 @default.
• W4382932015 cites W2794850401 @default.
• W4382932015 cites W2896567003 @default.
• W4382932015 cites W2901613361 @default.
• W4382932015 cites W2912326177 @default.
• W4382932015 cites W2916703549 @default.
• W4382932015 cites W2944502313 @default.
• W4382932015 cites W2968154398 @default.
• W4382932015 cites W2987058388 @default.
• W4382932015 cites W2988116898 @default.
• W4382932015 cites W2991113678 @default.
• W4382932015 cites W2993269442 @default.
• W4382932015 cites W3023625297 @default.
• W4382932015 cites W3044228405 @default.
• W4382932015 cites W3044711545 @default.
• W4382932015 cites W3048831280 @default.
• W4382932015 cites W3093728544 @default.
• W4382932015 cites W3135152432 @default.
• W4382932015 cites W3152829371 @default.
• W4382932015 cites W3216135524 @default.
• W4382932015 cites W4226039452 @default.
• W4382932015 cites W4285010816 @default.
• W4382932015 doi "https://doi.org/10.1530/raf-23-0015" @default.
• W4382932015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37399204" @default.
• W4382932015 hasPublicationYear "2023" @default.
• W4382932015 type Work @default.
• W4382932015 citedByCount "0" @default.
• W4382932015 crossrefType "journal-article" @default.
• W4382932015 hasAuthorship W4382932015A5011279938 @default.
• W4382932015 hasAuthorship W4382932015A5037763463 @default.
• W4382932015 hasAuthorship W4382932015A5069733342 @default.
• W4382932015 hasBestOaLocation W43829320151 @default.
• W4382932015 hasConcept C121752807 @default.
• W4382932015 hasConcept C126322002 @default.
• W4382932015 hasConcept C2776210078 @default.
• W4382932015 hasConcept C2777688143 @default.
• W4382932015 hasConcept C2779134260 @default.
• W4382932015 hasConcept C2779234561 @default.
• W4382932015 hasConcept C2779750884 @default.
• W4382932015 hasConcept C2908647359 @default.
• W4382932015 hasConcept C42407357 @default.
• W4382932015 hasConcept C54355233 @default.
• W4382932015 hasConcept C71924100 @default.
• W4382932015 hasConcept C86803240 @default.
• W4382932015 hasConcept C99454951 @default.
• W4382932015 hasConceptScore W4382932015C121752807 @default.
• W4382932015 hasConceptScore W4382932015C126322002 @default.
• W4382932015 hasConceptScore W4382932015C2776210078 @default.
• W4382932015 hasConceptScore W4382932015C2777688143 @default.
• W4382932015 hasConceptScore W4382932015C2779134260 @default.
• W4382932015 hasConceptScore W4382932015C2779234561 @default.
• W4382932015 hasConceptScore W4382932015C2779750884 @default.
• W4382932015 hasConceptScore W4382932015C2908647359 @default.
• W4382932015 hasConceptScore W4382932015C42407357 @default.
• W4382932015 hasConceptScore W4382932015C54355233 @default.
• W4382932015 hasConceptScore W4382932015C71924100 @default.
• W4382932015 hasConceptScore W4382932015C86803240 @default.
• W4382932015 hasConceptScore W4382932015C99454951 @default.
• W4382932015 hasIssue "3" @default.
• W4382932015 hasLocation W43829320151 @default.

• next