Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382988925> ?p ?o ?g. }
- W4382988925 endingPage "125593" @default.
- W4382988925 startingPage "125593" @default.
- W4382988925 abstract "Mechanical properties appropriate to native tissues, as an essential component in bone tissue engineering scaffolds, plays a significant role in tissue formation. In the current study, Poly-3 hydroxybutyrate-chitosan (PC) scaffolds reinforced with graphene oxide (GO) were made by the electrospinning method. The addition of GO led to a decrease in fibers diameter, an increase in thermal capacity and an improvement in the surface hydrophilicity of nanocomposite scaffolds. A significant increase in the mechanical properties of PC/GO (PCG) nanocomposite scaffolds was achieved due to the inherent strength of GO as well as its uniform dispersion throughout the polymeric matrix owing to hydrogen bonding and polar interactions. Also, lower biological degradation of the scaffolds (~30% in 100 days) due to the presence of GO provides essential mechanical support for bone regeneration. In addition, the bioactivity results showed that GO reinforcement significantly increases the biomineralization on the surface of the scaffolds. Evaluating cell adhesion and proliferation, as well as ALP activity of MG-63 cells on PC and PCG scaffolds indicated the positive effect of GO on scaffolds' biocompatibility. Overall, the improvement of physicochemical, mechanical, and biological properties of GO-reinforced scaffolds shows the potential of PCG nanocomposite scaffolds for bone tissue engineering." @default.
- W4382988925 created "2023-07-04" @default.
- W4382988925 creator A5002673706 @default.
- W4382988925 creator A5028538649 @default.
- W4382988925 creator A5090175637 @default.
- W4382988925 creator A5092387724 @default.
- W4382988925 date "2023-08-01" @default.
- W4382988925 modified "2023-10-15" @default.
- W4382988925 title "Investigation of physical, mechanical and biological properties of polyhydroxybutyrate-chitosan/graphene oxide nanocomposite scaffolds for bone tissue engineering applications" @default.
- W4382988925 cites W1473330989 @default.
- W4382988925 cites W1883141367 @default.
- W4382988925 cites W1895764896 @default.
- W4382988925 cites W1966082216 @default.
- W4382988925 cites W1976875501 @default.
- W4382988925 cites W1976929008 @default.
- W4382988925 cites W1977791017 @default.
- W4382988925 cites W1980133221 @default.
- W4382988925 cites W1982199874 @default.
- W4382988925 cites W2010971702 @default.
- W4382988925 cites W2026823754 @default.
- W4382988925 cites W2032433245 @default.
- W4382988925 cites W2033241952 @default.
- W4382988925 cites W2035445369 @default.
- W4382988925 cites W2042163001 @default.
- W4382988925 cites W2051091991 @default.
- W4382988925 cites W2056113284 @default.
- W4382988925 cites W2056689812 @default.
- W4382988925 cites W2073365814 @default.
- W4382988925 cites W2075282047 @default.
- W4382988925 cites W2106763677 @default.
- W4382988925 cites W2113867563 @default.
- W4382988925 cites W2115473959 @default.
- W4382988925 cites W2126729829 @default.
- W4382988925 cites W2146564548 @default.
- W4382988925 cites W2152621785 @default.
- W4382988925 cites W2264565970 @default.
- W4382988925 cites W2287835579 @default.
- W4382988925 cites W2292254066 @default.
- W4382988925 cites W2335153281 @default.
- W4382988925 cites W2338093569 @default.
- W4382988925 cites W2344793984 @default.
- W4382988925 cites W2464434438 @default.
- W4382988925 cites W2469576975 @default.
- W4382988925 cites W2514473071 @default.
- W4382988925 cites W2514697151 @default.
- W4382988925 cites W2540661720 @default.
- W4382988925 cites W2576858833 @default.
- W4382988925 cites W2584546405 @default.
- W4382988925 cites W2591049275 @default.
- W4382988925 cites W2606830215 @default.
- W4382988925 cites W2613021314 @default.
- W4382988925 cites W2618899140 @default.
- W4382988925 cites W2753739579 @default.
- W4382988925 cites W2757847090 @default.
- W4382988925 cites W2765955973 @default.
- W4382988925 cites W2769685187 @default.
- W4382988925 cites W2792536000 @default.
- W4382988925 cites W2794528450 @default.
- W4382988925 cites W2795158562 @default.
- W4382988925 cites W2803322827 @default.
- W4382988925 cites W2805772373 @default.
- W4382988925 cites W2887284421 @default.
- W4382988925 cites W2890127780 @default.
- W4382988925 cites W2895544837 @default.
- W4382988925 cites W2905511865 @default.
- W4382988925 cites W2908124046 @default.
- W4382988925 cites W2908215685 @default.
- W4382988925 cites W2908554523 @default.
- W4382988925 cites W2911961875 @default.
- W4382988925 cites W2912880623 @default.
- W4382988925 cites W2921359266 @default.
- W4382988925 cites W292630114 @default.
- W4382988925 cites W2942582569 @default.
- W4382988925 cites W2943850123 @default.
- W4382988925 cites W2946510943 @default.
- W4382988925 cites W2953761810 @default.
- W4382988925 cites W2959157793 @default.
- W4382988925 cites W2968050862 @default.
- W4382988925 cites W2985058190 @default.
- W4382988925 cites W2997303135 @default.
- W4382988925 cites W2998910909 @default.
- W4382988925 cites W3004129169 @default.
- W4382988925 cites W3012118402 @default.
- W4382988925 cites W3031383486 @default.
- W4382988925 cites W3041514436 @default.
- W4382988925 cites W3049134750 @default.
- W4382988925 cites W3084316264 @default.
- W4382988925 cites W3094412289 @default.
- W4382988925 cites W3095256335 @default.
- W4382988925 cites W3130242812 @default.
- W4382988925 cites W3191499526 @default.
- W4382988925 cites W3198993921 @default.
- W4382988925 cites W4286687892 @default.
- W4382988925 cites W4319875661 @default.
- W4382988925 doi "https://doi.org/10.1016/j.ijbiomac.2023.125593" @default.
- W4382988925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37406897" @default.
- W4382988925 hasPublicationYear "2023" @default.
- W4382988925 type Work @default.