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• W4383058596 abstract "The risk factors for persistent fatigue and cognitive complaints after infection with SARS-CoV-2 and the underlying pathophysiology are largely unknown. Both clinical factors and cognitive-behavioural factors have been suggested to play a role in the perpetuation of complaints. A neurobiological aetiology, such as neuroinflammation, could be the underlying pathophysiological mechanism for persisting complaints.To unravel factors associated with persisting complaints, VeCosCO will compare individuals with and without persistent fatigue and cognitive complaints >3 months after infection with SARS-CoV-2. The study consists of two work packages. The first work package aims to (1) investigate the relation between persisting complaints and neuropsychological functioning; (2) determine risk factors and at-risk phenotypes for the development of persistent fatigue and cognitive complaints, including the presence of postexertional malaise and (3) describe consequences of persistent complaints on quality of life, healthcare consumption and physical functioning. The second work package aims to (1) determine the presence of neuroinflammation with [18F]DPA-714 whole-body positron emission tomography (PET) scans in patients with persisting complaints and (2) explore the relationship between (neuro)inflammation and brain structure and functioning measured with MRI.This is a prospective case-control study in participants with and without persistent fatigue and cognitive complaints, >3 months after laboratory-confirmed SARS-CoV-2 infection. Participants will be mainly included from existing COVID-19 cohorts in the Netherlands covering the full spectrum of COVID-19 acute disease severity. Primary outcomes are neuropsychological functioning, postexertional malaise, neuroinflammation measured using [18F]DPA-714 PET, and brain functioning and structure using (f)MRI.Work package 1 (NL79575.018.21) and 2 (NL77033.029.21) were approved by the medical ethical review board of the Amsterdam University Medical Centers (The Netherlands). Informed consent is required prior to participation in the study. Results of this study will be submitted for publication in peer-reviewed journals and shared with the key population." @default.
• W4383058596 created "2023-07-05" @default.
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• W4383058596 date "2023-06-01" @default.
• W4383058596 modified "2023-10-12" @default.
• W4383058596 title "Neurobiological basis and risk factors of persistent fatigue and concentration problems after COVID-19: study protocol for a prospective case–control study (VeCosCO)" @default.
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• W4383058596 cites W1978276741 @default.
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• W4383058596 cites W1986014448 @default.
• W4383058596 cites W2001466921 @default.
• W4383058596 cites W2017307521 @default.
• W4383058596 cites W2030894553 @default.
• W4383058596 cites W2052717384 @default.
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• W4383058596 cites W2096657471 @default.
• W4383058596 cites W2098287790 @default.
• W4383058596 cites W2115352750 @default.
• W4383058596 cites W2129965408 @default.
• W4383058596 cites W2138123424 @default.
• W4383058596 cites W2139994949 @default.
• W4383058596 cites W2144544687 @default.
• W4383058596 cites W2151487996 @default.
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• W4383058596 cites W2170892587 @default.
• W4383058596 cites W2192451650 @default.
• W4383058596 cites W2507988981 @default.
• W4383058596 cites W2605220880 @default.
• W4383058596 cites W2612027047 @default.
• W4383058596 cites W2673124669 @default.
• W4383058596 cites W2804514583 @default.
• W4383058596 cites W2900540791 @default.
• W4383058596 cites W2921515016 @default.
• W4383058596 cites W2945073425 @default.
• W4383058596 cites W2948345224 @default.
• W4383058596 cites W2976680862 @default.
• W4383058596 cites W3037535840 @default.
• W4383058596 cites W3084818633 @default.
• W4383058596 cites W3088800697 @default.
• W4383058596 cites W3092826477 @default.
• W4383058596 cites W3093632019 @default.
• W4383058596 cites W3109863006 @default.
• W4383058596 cites W3114155216 @default.
• W4383058596 cites W3114198710 @default.
• W4383058596 cites W3119354442 @default.
• W4383058596 cites W3125396713 @default.
• W4383058596 cites W3131561956 @default.
• W4383058596 cites W3137239897 @default.
• W4383058596 cites W3141288379 @default.
• W4383058596 cites W3151661477 @default.
• W4383058596 cites W3156568658 @default.
• W4383058596 cites W3182592523 @default.
• W4383058596 cites W3185740435 @default.
• W4383058596 cites W3186044681 @default.
• W4383058596 cites W3196418672 @default.
• W4383058596 cites W3200834066 @default.
• W4383058596 cites W3203210084 @default.
• W4383058596 cites W3207752238 @default.
• W4383058596 cites W3217300911 @default.
• W4383058596 cites W4200066487 @default.
• W4383058596 cites W4205536614 @default.
• W4383058596 cites W4210467661 @default.
• W4383058596 cites W4220784902 @default.
• W4383058596 cites W4223455525 @default.
• W4383058596 cites W4225839404 @default.

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