Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383106562> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W4383106562 abstract "Introduction: Gut microbiota (GM) is an essential mediator in the health of GM and has been identified as the origin of several diseases by influencing cell signaling and T cell receptor pathways in the central nervous system. Several microRNAs participate in signaling networks through GM intervention. The interaction between GM and miRNAs plays a crucial role in vascular dysfunction. GM can metabolize L-carnitine, choline, and phosphatidylcholine and produce vascular-toxic metabolites such as trimethylamine-Noxide (TMAO), which is associated with the atherosclerotic process. Nutrology and dietary therapy represent important strategies, especially with the use of plant-derived miRNAs to modify GM. Objective: To carry out a systematic review to highlight the main roles of the gut microbiota and microRNAs in cardiovascular disease events. Methods: The present study followed a concise systematic review model (PRISMA). The literary search process was carried out from March to May 2023 and was developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, using scientific articles from 2002 to 2022. The low quality of evidence was attributed to reports of cases, editorials, and brief communications, according to the GRADE instrument. The risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: The total of 126 studies were found for eligibility analysis, and then 42 of the 64 total studies were selected for this systematic review. According to the GRADE instrument, most studies showed homogeneity in their results, with X2 =88.7%>50%. It was concluded that the gut microbiota can be influenced by diet, genetics, and environmental factors. Changes in the microbial population can lead to multiple diseases, including cardiovascular disease. miRNAs have been known as important regulators of several biological functions, and are also involved in the pathogenesis of cardiovascular diseases. There is evidence that disturbances in the gut microbiota and derived metabolites impair the development of atherosclerotic cardiovascular disease. Studies have shown that YRNAs belonging to extracellular vesicles and their fragments play important roles in the initiation, progression, and diagnosis of atherosclerosis." @default.
- W4383106562 created "2023-07-05" @default.
- W4383106562 creator A5048122121 @default.
- W4383106562 creator A5056405636 @default.
- W4383106562 date "2023-07-03" @default.
- W4383106562 modified "2023-09-30" @default.
- W4383106562 title "Major roles of the gut microbiota and microRNAs in cardiovascular disease events: a systematic review" @default.
- W4383106562 doi "https://doi.org/10.54448/ijn23231" @default.
- W4383106562 hasPublicationYear "2023" @default.
- W4383106562 type Work @default.
- W4383106562 citedByCount "0" @default.
- W4383106562 crossrefType "journal-article" @default.
- W4383106562 hasAuthorship W4383106562A5048122121 @default.
- W4383106562 hasAuthorship W4383106562A5056405636 @default.
- W4383106562 hasBestOaLocation W43831065621 @default.
- W4383106562 hasConcept C104317684 @default.
- W4383106562 hasConcept C126322002 @default.
- W4383106562 hasConcept C145059251 @default.
- W4383106562 hasConcept C189708586 @default.
- W4383106562 hasConcept C203014093 @default.
- W4383106562 hasConcept C2776478404 @default.
- W4383106562 hasConcept C2779134260 @default.
- W4383106562 hasConcept C2779473830 @default.
- W4383106562 hasConcept C42407357 @default.
- W4383106562 hasConcept C539455810 @default.
- W4383106562 hasConcept C54355233 @default.
- W4383106562 hasConcept C55493867 @default.
- W4383106562 hasConcept C60644358 @default.
- W4383106562 hasConcept C71924100 @default.
- W4383106562 hasConcept C86803240 @default.
- W4383106562 hasConcept C95190672 @default.
- W4383106562 hasConceptScore W4383106562C104317684 @default.
- W4383106562 hasConceptScore W4383106562C126322002 @default.
- W4383106562 hasConceptScore W4383106562C145059251 @default.
- W4383106562 hasConceptScore W4383106562C189708586 @default.
- W4383106562 hasConceptScore W4383106562C203014093 @default.
- W4383106562 hasConceptScore W4383106562C2776478404 @default.
- W4383106562 hasConceptScore W4383106562C2779134260 @default.
- W4383106562 hasConceptScore W4383106562C2779473830 @default.
- W4383106562 hasConceptScore W4383106562C42407357 @default.
- W4383106562 hasConceptScore W4383106562C539455810 @default.
- W4383106562 hasConceptScore W4383106562C54355233 @default.
- W4383106562 hasConceptScore W4383106562C55493867 @default.
- W4383106562 hasConceptScore W4383106562C60644358 @default.
- W4383106562 hasConceptScore W4383106562C71924100 @default.
- W4383106562 hasConceptScore W4383106562C86803240 @default.
- W4383106562 hasConceptScore W4383106562C95190672 @default.
- W4383106562 hasIssue "2" @default.
- W4383106562 hasLocation W43831065621 @default.
- W4383106562 hasOpenAccess W4383106562 @default.
- W4383106562 hasPrimaryLocation W43831065621 @default.
- W4383106562 hasRelatedWork W3027459656 @default.
- W4383106562 hasRelatedWork W3082854370 @default.
- W4383106562 hasRelatedWork W3117110396 @default.
- W4383106562 hasRelatedWork W3134414398 @default.
- W4383106562 hasRelatedWork W4207082034 @default.
- W4383106562 hasRelatedWork W4226154391 @default.
- W4383106562 hasRelatedWork W4226383011 @default.
- W4383106562 hasRelatedWork W4289667130 @default.
- W4383106562 hasRelatedWork W4313625070 @default.
- W4383106562 hasRelatedWork W4315436681 @default.
- W4383106562 hasVolume "16" @default.
- W4383106562 isParatext "false" @default.
- W4383106562 isRetracted "false" @default.
- W4383106562 workType "article" @default.