FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383186443> ?p ?o ?g. }

• W4383186443 abstract "Desmodus rotundus, vampire bats, transmit dangerous infections, and brucellosis is a hazardous zoonotic disease, two adversities that coexist in the subtropical and tropical areas of the American continent. Here, we report a 47.89% Brucella infection prevalence in a colony of vampire bats inhabiting the tropical rainforest of Costa Rica. The bacterium induced placentitis and fetal death in bats. Wide-range phenotypic and genotypic characterization placed the Brucella organisms as a new pathogenic species named Brucella nosferati sp. nov., isolated from bat tissues, including the salivary glands, suggesting feeding behavior might favor transmission to their prey. Overall analyses placed B. nosferati as the etiological agent of a reported canine brucellosis case, demonstrating its potential for infecting other hosts. To assess the putative prey hosts, we analyzed the intestinal contents of 14 infected and 23 non-infected bats by proteomics. A total of 54,508 peptides sorted into 7,203 unique peptides corresponding to 1,521 proteins were identified. Twenty-three wildlife and domestic taxa, including humans, were foraged by B. nosferati-infected D. rotundus, suggesting contact of this bacterium with a broad range of hosts. Our approach is appropriate for detecting, in a single study, the prey preferences of vampire bats in a diverse area, demonstrating its suitability for control strategies where vampire bats thrive. IMPORTANCE The discovery that a high proportion of vampire bats in a tropical area is infected with pathogenic Brucella nosferati and that bats forage on humans and many wild and domestic animals is relevant from the perspective of emerging disease prevention. Indeed, bats harboring B. nosferati in their salivary glands may transmit this pathogenic bacterium to other hosts. This potential is not trivial since, besides the demonstrated pathogenicity, this bacterium possesses all the required virulent arsenal of dangerous Brucella organisms, including those that are zoonotic for humans. Our work has settled the basis for future surveillance actions in brucellosis control programs where these infected bats thrive. Moreover, our strategy to identify the foraging range of bats may be adapted for exploring the feeding habits of diverse animals, including arthropod vectors of infectious diseases, and therefore of interest to a broader audience besides experts on Brucella and bats." @default.
• W4383186443 created "2023-07-06" @default.
• W4383186443 creator A5006750908 @default.
• W4383186443 creator A5008277622 @default.
• W4383186443 creator A5008450000 @default.
• W4383186443 creator A5009526654 @default.
• W4383186443 creator A5011211828 @default.
• W4383186443 creator A5018088957 @default.
• W4383186443 creator A5020350124 @default.
• W4383186443 creator A5022856064 @default.
• W4383186443 creator A5034153393 @default.
• W4383186443 creator A5046168885 @default.
• W4383186443 creator A5070386713 @default.
• W4383186443 creator A5070680440 @default.
• W4383186443 creator A5071510096 @default.
• W4383186443 creator A5079688277 @default.
• W4383186443 creator A5079786998 @default.
• W4383186443 creator A5085098159 @default.
• W4383186443 creator A5089645546 @default.
• W4383186443 creator A5092401781 @default.
• W4383186443 creator A5092401782 @default.
• W4383186443 date "2023-08-24" @default.
• W4383186443 modified "2023-10-18" @default.
• W4383186443 title "Virulent <i>Brucella nosferati</i> infecting <i>Desmodus rotundus</i> has emerging potential due to the broad foraging range of its bat host for humans and wild and domestic animals" @default.
• W4383186443 cites W1597962494 @default.
• W4383186443 cites W1966391444 @default.
• W4383186443 cites W1968415111 @default.
• W4383186443 cites W1969289536 @default.
• W4383186443 cites W1972145956 @default.
• W4383186443 cites W1982240324 @default.
• W4383186443 cites W1997485981 @default.
• W4383186443 cites W2005188513 @default.
• W4383186443 cites W2012120516 @default.
• W4383186443 cites W2016816974 @default.
• W4383186443 cites W2017708520 @default.
• W4383186443 cites W2019031186 @default.
• W4383186443 cites W2021623747 @default.
• W4383186443 cites W2026285384 @default.
• W4383186443 cites W2026741859 @default.
• W4383186443 cites W2028445106 @default.
• W4383186443 cites W2047708864 @default.
• W4383186443 cites W2058276097 @default.
• W4383186443 cites W2060131461 @default.
• W4383186443 cites W2063145457 @default.
• W4383186443 cites W2071891769 @default.
• W4383186443 cites W2076496180 @default.
• W4383186443 cites W2076518009 @default.
• W4383186443 cites W2090311317 @default.
• W4383186443 cites W2107772251 @default.
• W4383186443 cites W2108234281 @default.
• W4383186443 cites W2137342556 @default.
• W4383186443 cites W2141052558 @default.
• W4383186443 cites W2141993180 @default.
• W4383186443 cites W2149529908 @default.
• W4383186443 cites W2152047512 @default.
• W4383186443 cites W2153726727 @default.
• W4383186443 cites W2162822395 @default.
• W4383186443 cites W2163277422 @default.
• W4383186443 cites W2163524374 @default.
• W4383186443 cites W2297773358 @default.
• W4383186443 cites W2335090397 @default.
• W4383186443 cites W2421569084 @default.
• W4383186443 cites W2460832886 @default.
• W4383186443 cites W2523550005 @default.
• W4383186443 cites W2582671701 @default.
• W4383186443 cites W2609921155 @default.
• W4383186443 cites W2731991504 @default.
• W4383186443 cites W2742847546 @default.
• W4383186443 cites W2742935565 @default.
• W4383186443 cites W2774632352 @default.
• W4383186443 cites W2893869999 @default.
• W4383186443 cites W2897458932 @default.
• W4383186443 cites W2949182334 @default.
• W4383186443 cites W2949848068 @default.
• W4383186443 cites W2952167528 @default.
• W4383186443 cites W2953658159 @default.
• W4383186443 cites W2987186471 @default.
• W4383186443 cites W3010101050 @default.
• W4383186443 cites W3011058138 @default.
• W4383186443 cites W3046562084 @default.
• W4383186443 cites W3093368596 @default.
• W4383186443 cites W3134433025 @default.
• W4383186443 cites W3160348865 @default.
• W4383186443 cites W3175619154 @default.
• W4383186443 cites W3196415724 @default.
• W4383186443 cites W3216998658 @default.
• W4383186443 cites W4200073179 @default.
• W4383186443 cites W4212967725 @default.
• W4383186443 cites W4213292497 @default.
• W4383186443 cites W4214915285 @default.
• W4383186443 cites W4230128183 @default.
• W4383186443 cites W4254535786 @default.
• W4383186443 cites W4287143295 @default.
• W4383186443 cites W4312525054 @default.
• W4383186443 cites W4317871407 @default.
• W4383186443 cites W4382314792 @default.
• W4383186443 doi "https://doi.org/10.1128/msphere.00061-23" @default.
• W4383186443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37404031" @default.
• W4383186443 hasPublicationYear "2023" @default.
• W4383186443 type Work @default.

• next