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• W4383197129 abstract "Newcastle disease (ND), avian influenza (AI, H5N8), and infectious bronchitis (IB) are important diseases in the poultry industry and cause significant losses. Vaccination is the most practical method for controlling infectious diseases. To reduce vaccination costs and several disorders in poultry farms, using herbal water supplements for immunomodulation with vaccination is critical to improving or preventing some conditions in the poultry industry. However, drinking water supplementation of ginger extract (GE)/propolis extract (PE) alone/in combination may increase broilers' humoral and cellular immunity due to the immunomodulatory effects of ginger and propolis. This protocol aimed to see how GE/PE alone or in combination improved the immunity, immune organ gene expression, and histology of the immune organs of broilers for 35 days after vaccination against NDV, H5N8, IBV, and IBDV. The chicks were dispensed into five groups according to GE and/or PE with vaccination. The control group was offered normal drinking water without any supplements or vaccinations. The GE group was supplemented with ginger extract (1 ml/Liter drinking water) in the drinking water before and after vaccination for 2 and 3 days, respectively. The GE+PE group was supplemented with GE (0.5 ml/Liter drinking water) and PE (0.5 ml/Liter drinking water) in the drinking water before and after vaccination for 2 and 3 days, respectively. The PE group was supplemented with propolis extract (1 ml/Liter drinking water) in the drinking water before and after vaccination for 2 and 3 days, respectively. The fifth group was the vaccinated untreated group. This experiment showed the immunomodulatory properties of GE and/or PE against three common diseases, NDV, AI, and IB, in broiler chicken farms for 35 days applied to a vaccination program. Thus, ginger extract and propolis extract supplementation in drinking water increased antibody titer, INF, IL10, and IL2 and TLR3 gene expression in the bursa of Fabricius, thymus, and spleen, respectively, as well as cellular immunity as indicated by increased CD3, CD4, and CD8 in the bursa of Fabricius, thymus, and spleen, respectively, with normal lymphocytes in the medulla of the bursa, thymus, and spleen. In conclusion, propolis extracts alone or with GE improved all of the metrics mentioned above without harming the histology of the immune organs." @default.
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• W4383197129 date "2023-10-01" @default.
• W4383197129 modified "2023-10-16" @default.
• W4383197129 title "Effects of ginger extract and/or propolis extract on immune system parameters of vaccinated broilers" @default.
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• W4383197129 doi "https://doi.org/10.1016/j.psj.2023.102903" @default.
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