Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383215512> ?p ?o ?g. }
- W4383215512 abstract "Abstract Diabetic foot ulcers are chronic wounds that affect millions and increase the risk of amputation and mortality, highlighting the critical need for their early detection. Recent demonstrations of wearable sensors enable real‐time wound assessment, but they rely on bulky electronics, making them difficult to interface with wounds. Herein, a miniaturized, wireless, battery‐free wound monitor that measures lactate in real‐time and seamlessly integrates with bandages for conformal attachment to the wound bed is introduced. Lactate is selected due to its multifaceted role in initiating healing. Studies in healthy and diabetic mice reveal distinct lactate profiles for normal and impaired healing wounds. A mathematical model based on the sensor data predicts wound closure rate within the first 3 days post‐injury with ≈76% accuracy, which increases to ≈83% when pH is included. These studies underscore the significance of monitoring biomarkers during the inflammation phase, which can offer several benefits, including short‐term use of wound monitors and their easy removal, resulting in lower risks of injury and infection at the wound site. Improvements in prediction accuracy can be achieved by designing mathematical models that build on multiple wound parameters such as pro‐inflammatory and metabolic markers. Achieving this goal will require designing multi‐analyte wound monitors." @default.
- W4383215512 created "2023-07-06" @default.
- W4383215512 creator A5000988147 @default.
- W4383215512 creator A5002023034 @default.
- W4383215512 creator A5008577821 @default.
- W4383215512 creator A5011182849 @default.
- W4383215512 creator A5025999561 @default.
- W4383215512 creator A5030036035 @default.
- W4383215512 creator A5032101070 @default.
- W4383215512 creator A5032355633 @default.
- W4383215512 creator A5037531387 @default.
- W4383215512 creator A5046070608 @default.
- W4383215512 creator A5048728346 @default.
- W4383215512 creator A5049300172 @default.
- W4383215512 creator A5063690894 @default.
- W4383215512 creator A5070624185 @default.
- W4383215512 creator A5082892851 @default.
- W4383215512 creator A5087338208 @default.
- W4383215512 creator A5087908774 @default.
- W4383215512 creator A5091731986 @default.
- W4383215512 creator A5092262215 @default.
- W4383215512 date "2023-07-21" @default.
- W4383215512 modified "2023-09-26" @default.
- W4383215512 title "A Miniaturized, Battery‐Free, Wireless Wound Monitor That Predicts Wound Closure Rate Early" @default.
- W4383215512 cites W1441236973 @default.
- W4383215512 cites W1532224000 @default.
- W4383215512 cites W1757875555 @default.
- W4383215512 cites W1834049370 @default.
- W4383215512 cites W1967162280 @default.
- W4383215512 cites W1991403326 @default.
- W4383215512 cites W1997789613 @default.
- W4383215512 cites W2007129300 @default.
- W4383215512 cites W2061537454 @default.
- W4383215512 cites W2066874563 @default.
- W4383215512 cites W2113869753 @default.
- W4383215512 cites W2123983543 @default.
- W4383215512 cites W2137619255 @default.
- W4383215512 cites W2160991147 @default.
- W4383215512 cites W2345435825 @default.
- W4383215512 cites W2353982544 @default.
- W4383215512 cites W2553413222 @default.
- W4383215512 cites W2625161454 @default.
- W4383215512 cites W2767821413 @default.
- W4383215512 cites W2780266423 @default.
- W4383215512 cites W2787894218 @default.
- W4383215512 cites W2800734146 @default.
- W4383215512 cites W2808115170 @default.
- W4383215512 cites W2869477050 @default.
- W4383215512 cites W2896448766 @default.
- W4383215512 cites W2898378414 @default.
- W4383215512 cites W2908225639 @default.
- W4383215512 cites W2908711986 @default.
- W4383215512 cites W2909800157 @default.
- W4383215512 cites W2912753638 @default.
- W4383215512 cites W2916107496 @default.
- W4383215512 cites W2938111732 @default.
- W4383215512 cites W2949308540 @default.
- W4383215512 cites W2955445861 @default.
- W4383215512 cites W2967533285 @default.
- W4383215512 cites W2969353819 @default.
- W4383215512 cites W2997669810 @default.
- W4383215512 cites W3016630914 @default.
- W4383215512 cites W3024399025 @default.
- W4383215512 cites W3036599147 @default.
- W4383215512 cites W3045646972 @default.
- W4383215512 cites W3090362906 @default.
- W4383215512 cites W3092441529 @default.
- W4383215512 cites W3093685942 @default.
- W4383215512 cites W3127812768 @default.
- W4383215512 cites W3129559940 @default.
- W4383215512 cites W3139358517 @default.
- W4383215512 cites W3158950609 @default.
- W4383215512 cites W3159164083 @default.
- W4383215512 cites W3160425451 @default.
- W4383215512 cites W3161909955 @default.
- W4383215512 cites W3178875152 @default.
- W4383215512 cites W3213000679 @default.
- W4383215512 cites W4200207177 @default.
- W4383215512 cites W4200502753 @default.
- W4383215512 cites W4205662372 @default.
- W4383215512 cites W4206534340 @default.
- W4383215512 cites W4210570020 @default.
- W4383215512 cites W4214761999 @default.
- W4383215512 cites W4220749927 @default.
- W4383215512 cites W4229456303 @default.
- W4383215512 cites W4283813169 @default.
- W4383215512 cites W4284885890 @default.
- W4383215512 cites W4286560842 @default.
- W4383215512 cites W4293833080 @default.
- W4383215512 cites W4299616802 @default.
- W4383215512 cites W4307181465 @default.
- W4383215512 cites W4309076178 @default.
- W4383215512 cites W4309835268 @default.
- W4383215512 cites W4310058384 @default.
- W4383215512 cites W4321481099 @default.
- W4383215512 cites W4360828136 @default.
- W4383215512 doi "https://doi.org/10.1002/adhm.202301280" @default.
- W4383215512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37407030" @default.
- W4383215512 hasPublicationYear "2023" @default.
- W4383215512 type Work @default.