FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383226464> ?p ?o ?g. }

• W4383226464 endingPage "5661" @default.
• W4383226464 startingPage "5645" @default.
• W4383226464 abstract "The growing incidence of oropharyngeal squamous cell carcinoma (OPSCC) calls for better understanding of the mutational landscape of such cases. Mucins (MUCs) are multifunctional glycoproteins expressed by the epithelial cells and may be associated with the epithelial tumour invasion and progression. The present study aimed at the analysis of the sequence of selected MUC6 and MUC16 gene fragments in the tumour, as well as the margin, samples obtained from 18 OPSCC patients. Possible associations between the detected mutations and the clinicopathological and demographic characteristics of the study group were analysed. Sanger sequencing and bioinformatic data analysis of the selected MUC6 and MUC16 cDNA fragments were performed. Our study found 13 and 3 mutations in MUC6 and MUC16, respectively. In particular, one novelty variant found that the MUC6 gene (chr11:1018257 A>T) was the most frequent across our cohort, in both the tumour and the margin samples, and was then classified as a high impact, stop-gain mutation. The current study found novel mutations in MUC6 and MUC16 providing new insight into the genetic alternation in mucin genes among the OPSCC patients. Further studies, including larger cohorts, are recommended to recognise the pattern in which the mutations affect oropharyngeal carcinogenesis." @default.
• W4383226464 created "2023-07-06" @default.
• W4383226464 creator A5006435025 @default.
• W4383226464 creator A5028985631 @default.
• W4383226464 creator A5033568796 @default.
• W4383226464 creator A5041462613 @default.
• W4383226464 creator A5041470722 @default.
• W4383226464 creator A5043922634 @default.
• W4383226464 creator A5044620964 @default.
• W4383226464 creator A5060893437 @default.
• W4383226464 creator A5067598040 @default.
• W4383226464 creator A5075697375 @default.
• W4383226464 date "2023-07-04" @default.
• W4383226464 modified "2023-09-25" @default.
• W4383226464 title "Sequencing Analysis of MUC6 and MUC16 Gene Fragments in Patients with Oropharyngeal Squamous Cell Carcinoma Reveals Novel Mutations: A Preliminary Study" @default.
• W4383226464 cites W1140542477 @default.
• W4383226464 cites W1970915933 @default.
• W4383226464 cites W2039478605 @default.
• W4383226464 cites W2047120971 @default.
• W4383226464 cites W2059145105 @default.
• W4383226464 cites W2062312459 @default.
• W4383226464 cites W2087439179 @default.
• W4383226464 cites W2133599168 @default.
• W4383226464 cites W2143238378 @default.
• W4383226464 cites W2150312232 @default.
• W4383226464 cites W2339723519 @default.
• W4383226464 cites W2417483443 @default.
• W4383226464 cites W2563363007 @default.
• W4383226464 cites W2588881450 @default.
• W4383226464 cites W2604486765 @default.
• W4383226464 cites W2615006138 @default.
• W4383226464 cites W2799699959 @default.
• W4383226464 cites W2802681048 @default.
• W4383226464 cites W2883796806 @default.
• W4383226464 cites W2885715971 @default.
• W4383226464 cites W2886328774 @default.
• W4383226464 cites W2903254254 @default.
• W4383226464 cites W2904887959 @default.
• W4383226464 cites W2909703266 @default.
• W4383226464 cites W2912891382 @default.
• W4383226464 cites W2925824549 @default.
• W4383226464 cites W2947215881 @default.
• W4383226464 cites W2964372340 @default.
• W4383226464 cites W3011793052 @default.
• W4383226464 cites W3015066429 @default.
• W4383226464 cites W3029661147 @default.
• W4383226464 cites W3040369893 @default.
• W4383226464 cites W3080350533 @default.
• W4383226464 cites W3087346324 @default.
• W4383226464 cites W3107533236 @default.
• W4383226464 cites W3119282350 @default.
• W4383226464 cites W3122988797 @default.
• W4383226464 cites W3128646645 @default.
• W4383226464 cites W3164572091 @default.
• W4383226464 cites W3179147530 @default.
• W4383226464 cites W3203367019 @default.
• W4383226464 cites W3215623542 @default.
• W4383226464 cites W4200015730 @default.
• W4383226464 cites W4200465511 @default.
• W4383226464 cites W4210575080 @default.
• W4383226464 cites W4220770411 @default.
• W4383226464 cites W4239909670 @default.
• W4383226464 cites W4283785295 @default.
• W4383226464 cites W4293515230 @default.
• W4383226464 cites W4312114664 @default.
• W4383226464 doi "https://doi.org/10.3390/cimb45070356" @default.
• W4383226464 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37504272" @default.
• W4383226464 hasPublicationYear "2023" @default.
• W4383226464 type Work @default.
• W4383226464 citedByCount "0" @default.
• W4383226464 crossrefType "journal-article" @default.
• W4383226464 hasAuthorship W4383226464A5006435025 @default.
• W4383226464 hasAuthorship W4383226464A5028985631 @default.
• W4383226464 hasAuthorship W4383226464A5033568796 @default.
• W4383226464 hasAuthorship W4383226464A5041462613 @default.
• W4383226464 hasAuthorship W4383226464A5041470722 @default.
• W4383226464 hasAuthorship W4383226464A5043922634 @default.
• W4383226464 hasAuthorship W4383226464A5044620964 @default.
• W4383226464 hasAuthorship W4383226464A5060893437 @default.
• W4383226464 hasAuthorship W4383226464A5067598040 @default.
• W4383226464 hasAuthorship W4383226464A5075697375 @default.
• W4383226464 hasBestOaLocation W43832264641 @default.
• W4383226464 hasConcept C104317684 @default.
• W4383226464 hasConcept C142724271 @default.
• W4383226464 hasConcept C179264091 @default.
• W4383226464 hasConcept C501734568 @default.
• W4383226464 hasConcept C502942594 @default.
• W4383226464 hasConcept C54355233 @default.
• W4383226464 hasConcept C555283112 @default.
• W4383226464 hasConcept C71924100 @default.
• W4383226464 hasConcept C76818968 @default.
• W4383226464 hasConcept C86803240 @default.
• W4383226464 hasConceptScore W4383226464C104317684 @default.
• W4383226464 hasConceptScore W4383226464C142724271 @default.
• W4383226464 hasConceptScore W4383226464C179264091 @default.
• W4383226464 hasConceptScore W4383226464C501734568 @default.
• W4383226464 hasConceptScore W4383226464C502942594 @default.
• W4383226464 hasConceptScore W4383226464C54355233 @default.

• next