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- W4383270559 abstract "Case report: A previously healthy 60-year-old woman presented to the dermatology clinic for a deep phenol peeling. A few minutes after the procedure, she had become confused and disoriented, so the neurology clinic was called. On the neurological assessment, the patient kept asking her sister where she was and how she got to the hospital. It was noted that the patient had deep anterograde amnesia and retrograde amnesia ranging from a few hours before the arrival at the hospital, with preserved episodic and semantic memories. The remainder of the neurologic exam was normal. She was submitted to basic laboratory evaluation, which showed no abnormalities. Brain magnetic resonance imagin showed a mild FLAIR (Fluid-Attenuated Inversion Recovery) hyperintensity on the left medial temporal lobe, without signal alterations in the DWI (diffusion-weighted imaging) image. After about 4 hours of the onset, the disorientation had resolved and she was discharged after 24 hours of observation, asymptomatic. Discussion: Phenol peeling is the most aggressive of all peels, and as this substance is absorbed by the skin, metabolized by the liver, and excreted by urine it is associated with systemic complications, such as cardiac arrhythmias and acute kidney injury. There are no previous reports of the occurrence of a transient global amnesia (TGA) episode after such a procedure, although it is known that it can be precipitated by physical exertion and psychological stress. The pathophysiology of a TGA episode is thought to be related to metabolic stress to the CA-1 subfield of the hippocampus. Although the association is unclear, we can make an assumption that phenol could have a disruptive metabolic effect on this particular brain area. Conclusion: We report a case of TGA preceded by a deep phenol peeling. Although it is impossible to establish causality in this case, it is important that the neurologist be aware that certain medical conditions, procedures and substance administration can be associated with TGA." @default.
- W4383270559 created "2023-07-06" @default.
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- W4383270559 date "2023-01-01" @default.
- W4383270559 modified "2023-09-24" @default.
- W4383270559 title "Transient global amnesia after a phenol peeling" @default.
- W4383270559 doi "https://doi.org/10.5327/1516-3180.141s1.444" @default.
- W4383270559 hasPublicationYear "2023" @default.
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