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- W4383301612 abstract "目的： 探讨胃底腺来源的泌酸腺型肿瘤，包括泌酸腺腺瘤（OGA）和胃底腺型腺癌（GA-FG）的临床病理学特征。 方法： 收集2019年1月至2022年3月厦门大学附属第一医院诊治的18例泌酸腺型肿瘤，回顾性分析18例患者的临床症状、内镜特征、病理形态学特点及免疫组织化学检测结果。 结果： 18例泌酸腺型肿瘤患者中，男性11例，女性7例，平均年龄54岁。临床主要表现为上腹部闷痛不适、反酸等症状。2例为多发病变，16例为单发病变，主要发生部位为胃底和胃体。以浅表隆起型和无蒂隆起型最为多见。病理形态学特点主要表现在腺体结构紊乱，主要由主细胞型细胞构成，其中散在混杂少量壁细胞。4例诊断OGA，11例诊断GA-FG，3例无法评估病变范围，诊断泌酸腺型肿瘤。免疫组织化学表达结果：肿瘤细胞Pepsinogen 1、MUC6、CD56、突触素呈弥漫阳性表达，幽门螺杆菌阳性4例，Ki-67阳性指数1%~20%。 结论： 泌酸腺型肿瘤临床发病率低，胃镜活检标本对判断泌酸腺型肿瘤是OGA还是GA-FG有一定困难，而内镜黏膜下剥离术（ESD）或内镜下黏膜切除术（EMR）切除标本可明确诊断，当胃镜活检标本无法明确诊断时，建议诊断为泌酸腺型肿瘤，临床则进一步行ESD或EMR手术切除。." @default.
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- W4383301612 date "2023-07-08" @default.
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- W4383301612 title "[Clinicopathological characteristics of 18 cases of oxyntic gland neoplasm from gastric fundic gland]." @default.
- W4383301612 doi "https://doi.org/10.3760/cma.j.cn112151-20221027-00891" @default.
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