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- W4383302655 abstract "Multimodal mass spectrometry imaging (MSI) is a leading approach for investigating the molecular processes within biological samples. The parallel detection of compounds including metabolites, lipids, proteins, and metal isotopes allows for a more holistic understanding of tissue microenvironments. Universal sample preparation is a primary enabler for samples of the same set to be run across multiple modalities. Using the same method and materials for a cohort of samples reduces any potential variability during sample preparation and allows for comparable analysis across analytical imaging techniques. Here, the MSI workflow is describing a sample preparation protocol for the analysis of three-dimensional (3D) cell culture models. The analysis of biologically relevant cultures by multimodal MSI offers a method in which models of cancer and disease can be studied for the use in early-stage drug development." @default.
- W4383302655 created "2023-07-07" @default.
- W4383302655 creator A5037048651 @default.
- W4383302655 date "2023-01-01" @default.
- W4383302655 modified "2023-09-24" @default.
- W4383302655 title "Multimodal Mass Spectrometry Imaging of an Aggregated 3D Cell Culture Model" @default.
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- W4383302655 doi "https://doi.org/10.1007/978-1-0716-3319-9_13" @default.
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