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• W4383313309 abstract "The effect of the antioxidant capacity of diet and its distribution across three meals on mortality risk among cancer patients remains unexplored. We aimed to prospectively investigate the association of dietary total antioxidant capacity (DAC) and its distribution across three meals with all-cause, cancer, and noncancer mortality among cancer survivors. We included 5,009 patients with cancer from the National Health and Nutrition Examination Survey conducted between 1999 and 2018. The adjusted hazard ratio (aHR) was estimated using the survey-weighted Cox proportional hazards model. During a median follow-up of 7.9 years, 1811 deaths, including 575 cancer-related deaths, were recorded. Among cancer survivors, compared with participants in the lowest quartile of total DAC from three meals, those in the highest quartile had a 24% decreased risk of noncancer mortality (aHR = 0.76, 95% confidence interval [CI]: 0.60–0.92), but not of all-cause and cancer mortality (each p trend &gt;0.1). However, this association became insignificant for total DAC after excluding dinner DAC. In addition, higher dinner DAC rather than breakfast or lunch DAC was associated with a 21% lower risk of all-cause mortality (aHR = 0.79, 95% CI: 0.65–0.98) and 28% lower risk of noncancer mortality (aHR = 0.72, 95% CI: 0.57–0.90). Similar associations were found for ΔDAC (dinner DAC − breakfast DAC) with noncancer mortality (aHR = 0.56, 95% CI: 0.38–0.83), but DAC was not associated with cancer mortality ( p trend &gt;0.3). Among cancer survivors, total DAC from three meals was associated with reduced noncancer mortality, with the primary effect attributable to increased DAC intake from dinner. Our findings emphasize that DAC consumption from dinner should be advocated to reduce mortality risk in cancer survivors." @default.
• W4383313309 created "2023-07-07" @default.
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• W4383313309 date "2023-07-06" @default.
• W4383313309 modified "2023-09-26" @default.
• W4383313309 title "Association of dietary total antioxidant capacity and its distribution across three meals with all-cause, cancer, and non-cancer mortality among cancer survivors: the US National Health and Nutrition Examination Survey, 1999–2018" @default.
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• W4383313309 doi "https://doi.org/10.3389/fnut.2023.1141380" @default.
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• W4383313309 hasPublicationYear "2023" @default.
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