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- W4383373615 abstract "<p>Immuno-PET of <sup>89</sup>Zr-DFO-CD69 Ab as a prognostic predictor after ICI treatment in a GBM mouse model. Survival follow-up of mice inoculated with GL261 cells, and evaluated by immuno-PET of <sup>89</sup>Zr-DFO-CD69 Ab, comparing treatment (ICI) group to control group (represented by orange and blue dots, respectively). <b>A,</b> Schematic showing timeline of tumor inoculation, ICI treatment, MRI, tail vein injection of <sup>89</sup>Zr-DFO-CD69 Ab, immuno-PET, and survival follow-up. <b>B,</b> The overall survival (OS) rates of the ICI-treated group and control group are plotted using Kaplan–Meier survival curves, with log-rank (Mantel–Cox) curve comparison test. <b>C,</b> Right, heat map display of Pearson correlation coefficient analysis between immuno-PET signals and survival in the two groups. Results are shown for each SUV measurement method (SUV<sub>max</sub>, SUV<sub>max</sub> TBR, SUV<sub>mean</sub>, and SUV<sub>mean</sub> TBR) in each immuno-PET designated time point (days 1, 2, 3, 4, and 6). Shown are representative data of two independent experiments, <i>n</i> = 4–5 mice per group (*, <i>P</i> < 0.05; **, <i>P</i> <0.01). Left, examples of scatter diagrams of Pearson correlation coefficient taken from immuno-PETs on day 2 of SUV<sub>max</sub> and SUV<sub>max</sub> TBR. Scattered dots represent individual mice, <i>n</i> = 4–5 mice per group.</p>" @default.
- W4383373615 created "2023-07-07" @default.
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- W4383373615 date "2023-07-06" @default.
- W4383373615 modified "2023-09-23" @default.
- W4383373615 title "FIGURE 5 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma" @default.
- W4383373615 doi "https://doi.org/10.1158/2767-9764.23635586" @default.
- W4383373615 hasPublicationYear "2023" @default.
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