Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383619148> ?p ?o ?g. }
- W4383619148 endingPage "104743" @default.
- W4383619148 startingPage "104743" @default.
- W4383619148 abstract "The significance of peripheral immunity in the pathogenesis and progression of Alzheimer’s diseases (AD) has been recognized. Brain-infiltrated peripheral immune components transporting across the blood–brain barrier (BBB) may reshape the central immune environment. However, mechanisms of how these components open the BBB for AD occurrence and development and correlations between peripheral and central immunity have not been fully explored. Herein, we formulate a hypothesis whereby peripheral immunity as a critical factor allows AD to progress. Peripheral central immune cell crosstalk is associated with early AD pathology and related risk factors. The damaged BBB permits peripheral immune cells to enter the central immune system to deprive its immune privilege promoting the progression toward developing AD. This review summarizes the influences of risk factors on peripheral immunity, alongside their functions, highlighting the concept of peripheral and central immunity as an integrated system in AD pathogenesis, which has received scant attention before." @default.
- W4383619148 created "2023-07-09" @default.
- W4383619148 creator A5017115279 @default.
- W4383619148 creator A5018928091 @default.
- W4383619148 creator A5026660665 @default.
- W4383619148 creator A5037491264 @default.
- W4383619148 creator A5075070793 @default.
- W4383619148 creator A5092428731 @default.
- W4383619148 date "2023-09-01" @default.
- W4383619148 modified "2023-09-25" @default.
- W4383619148 title "Crosstalk between peripheral immunity and central nervous system in Alzheimer’s disease" @default.
- W4383619148 cites W1516940938 @default.
- W4383619148 cites W1540420763 @default.
- W4383619148 cites W1602000691 @default.
- W4383619148 cites W1768846296 @default.
- W4383619148 cites W1810076817 @default.
- W4383619148 cites W1841850981 @default.
- W4383619148 cites W1946521533 @default.
- W4383619148 cites W1963517438 @default.
- W4383619148 cites W1971798829 @default.
- W4383619148 cites W1981621288 @default.
- W4383619148 cites W2004111877 @default.
- W4383619148 cites W2005471473 @default.
- W4383619148 cites W2006035554 @default.
- W4383619148 cites W2016229866 @default.
- W4383619148 cites W2020061739 @default.
- W4383619148 cites W2025946388 @default.
- W4383619148 cites W2049329367 @default.
- W4383619148 cites W2058146246 @default.
- W4383619148 cites W2070447896 @default.
- W4383619148 cites W2073813663 @default.
- W4383619148 cites W2074405990 @default.
- W4383619148 cites W2074800088 @default.
- W4383619148 cites W2075180511 @default.
- W4383619148 cites W2075539642 @default.
- W4383619148 cites W2076658253 @default.
- W4383619148 cites W2077459912 @default.
- W4383619148 cites W2085982747 @default.
- W4383619148 cites W2093241348 @default.
- W4383619148 cites W2098345971 @default.
- W4383619148 cites W2098613848 @default.
- W4383619148 cites W2101372125 @default.
- W4383619148 cites W2106914633 @default.
- W4383619148 cites W2114829829 @default.
- W4383619148 cites W2117000810 @default.
- W4383619148 cites W2120070267 @default.
- W4383619148 cites W2130583999 @default.
- W4383619148 cites W2130834754 @default.
- W4383619148 cites W2147904592 @default.
- W4383619148 cites W2155344647 @default.
- W4383619148 cites W2170654913 @default.
- W4383619148 cites W2170886136 @default.
- W4383619148 cites W2178866977 @default.
- W4383619148 cites W2195401907 @default.
- W4383619148 cites W2200279205 @default.
- W4383619148 cites W2257167523 @default.
- W4383619148 cites W2258002535 @default.
- W4383619148 cites W2271431941 @default.
- W4383619148 cites W2271499489 @default.
- W4383619148 cites W2275744255 @default.
- W4383619148 cites W2327752912 @default.
- W4383619148 cites W2331586707 @default.
- W4383619148 cites W2341105027 @default.
- W4383619148 cites W2510806376 @default.
- W4383619148 cites W2555314899 @default.
- W4383619148 cites W2577452028 @default.
- W4383619148 cites W2593036876 @default.
- W4383619148 cites W2608656781 @default.
- W4383619148 cites W2609542724 @default.
- W4383619148 cites W2737946846 @default.
- W4383619148 cites W2749751342 @default.
- W4383619148 cites W2756319919 @default.
- W4383619148 cites W2789907674 @default.
- W4383619148 cites W2796140394 @default.
- W4383619148 cites W2804234159 @default.
- W4383619148 cites W2805185070 @default.
- W4383619148 cites W2811371297 @default.
- W4383619148 cites W2887362069 @default.
- W4383619148 cites W2888970970 @default.
- W4383619148 cites W2889190248 @default.
- W4383619148 cites W2891010257 @default.
- W4383619148 cites W2895430781 @default.
- W4383619148 cites W2897433925 @default.
- W4383619148 cites W2900492873 @default.
- W4383619148 cites W2904597606 @default.
- W4383619148 cites W2911570417 @default.
- W4383619148 cites W2911778150 @default.
- W4383619148 cites W2942678593 @default.
- W4383619148 cites W2945276138 @default.
- W4383619148 cites W2951246796 @default.
- W4383619148 cites W2955261360 @default.
- W4383619148 cites W2956117347 @default.
- W4383619148 cites W2965040444 @default.
- W4383619148 cites W2966309623 @default.
- W4383619148 cites W2968609503 @default.
- W4383619148 cites W2970822018 @default.
- W4383619148 cites W2971770812 @default.
- W4383619148 cites W2976432777 @default.