Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383619439> ?p ?o ?g. }
- W4383619439 abstract "Abstract Here we present GlycanFinder, a database search and de novo sequencing tool for the analysis of intact glycopeptides from mass spectrometry data. GlycanFinder integrates peptide-based and glycan-based search strategies to address the challenge of complex fragmentation of glycopeptides. A deep learning model is designed to capture glycan tree structures and their fragment ions for de novo sequencing of glycans that do not exist in the database. We performed extensive analyses to validate the false discovery rates (FDRs) at both peptide and glycan levels and to evaluate GlycanFinder based on comprehensive benchmarks from previous community-based studies. Our results show that GlycanFinder achieved comparable performance to other leading glycoproteomics softwares in terms of both FDR control and the number of identifications. Moreover, GlycanFinder was also able to identify glycopeptides not found in existing databases. Finally, we conducted a mass spectrometry experiment for antibody N-linked glycosylation profiling that could distinguish isomeric peptides and glycans in four immunoglobulin G subclasses, which had been a challenging problem to previous studies." @default.
- W4383619439 created "2023-07-09" @default.
- W4383619439 creator A5013405579 @default.
- W4383619439 creator A5016522456 @default.
- W4383619439 creator A5019823063 @default.
- W4383619439 creator A5025185954 @default.
- W4383619439 creator A5029928314 @default.
- W4383619439 creator A5036028069 @default.
- W4383619439 creator A5055658148 @default.
- W4383619439 creator A5057912307 @default.
- W4383619439 creator A5058469124 @default.
- W4383619439 creator A5059755817 @default.
- W4383619439 creator A5085048979 @default.
- W4383619439 date "2023-07-08" @default.
- W4383619439 modified "2023-10-18" @default.
- W4383619439 title "Glycopeptide database search and de novo sequencing with PEAKS GlycanFinder enable highly sensitive glycoproteomics" @default.
- W4383619439 cites W1908224577 @default.
- W4383619439 cites W1979803040 @default.
- W4383619439 cites W1993450321 @default.
- W4383619439 cites W2013044141 @default.
- W4383619439 cites W2040470885 @default.
- W4383619439 cites W2062859898 @default.
- W4383619439 cites W2096057003 @default.
- W4383619439 cites W2110438218 @default.
- W4383619439 cites W2135078307 @default.
- W4383619439 cites W2157939022 @default.
- W4383619439 cites W2306311420 @default.
- W4383619439 cites W2409069109 @default.
- W4383619439 cites W2549976854 @default.
- W4383619439 cites W2736859409 @default.
- W4383619439 cites W2750804254 @default.
- W4383619439 cites W2752557010 @default.
- W4383619439 cites W2754240404 @default.
- W4383619439 cites W2767839389 @default.
- W4383619439 cites W2768087917 @default.
- W4383619439 cites W2804732351 @default.
- W4383619439 cites W2893720298 @default.
- W4383619439 cites W2903819617 @default.
- W4383619439 cites W2921437380 @default.
- W4383619439 cites W2945238312 @default.
- W4383619439 cites W2973321959 @default.
- W4383619439 cites W2979864756 @default.
- W4383619439 cites W2991106430 @default.
- W4383619439 cites W2992072079 @default.
- W4383619439 cites W3006972050 @default.
- W4383619439 cites W3010178213 @default.
- W4383619439 cites W3023376619 @default.
- W4383619439 cites W3036016037 @default.
- W4383619439 cites W3090230755 @default.
- W4383619439 cites W3093525434 @default.
- W4383619439 cites W3119627924 @default.
- W4383619439 cites W3133209323 @default.
- W4383619439 cites W3136924813 @default.
- W4383619439 cites W3167897985 @default.
- W4383619439 cites W3188243150 @default.
- W4383619439 cites W3208691473 @default.
- W4383619439 cites W3208915235 @default.
- W4383619439 cites W3214881753 @default.
- W4383619439 cites W4206121249 @default.
- W4383619439 cites W4220916669 @default.
- W4383619439 cites W4223538113 @default.
- W4383619439 cites W4311582770 @default.
- W4383619439 doi "https://doi.org/10.1038/s41467-023-39699-5" @default.
- W4383619439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37422459" @default.
- W4383619439 hasPublicationYear "2023" @default.
- W4383619439 type Work @default.
- W4383619439 citedByCount "1" @default.
- W4383619439 countsByYear W43836194392023 @default.
- W4383619439 crossrefType "journal-article" @default.
- W4383619439 hasAuthorship W4383619439A5013405579 @default.
- W4383619439 hasAuthorship W4383619439A5016522456 @default.
- W4383619439 hasAuthorship W4383619439A5019823063 @default.
- W4383619439 hasAuthorship W4383619439A5025185954 @default.
- W4383619439 hasAuthorship W4383619439A5029928314 @default.
- W4383619439 hasAuthorship W4383619439A5036028069 @default.
- W4383619439 hasAuthorship W4383619439A5055658148 @default.
- W4383619439 hasAuthorship W4383619439A5057912307 @default.
- W4383619439 hasAuthorship W4383619439A5058469124 @default.
- W4383619439 hasAuthorship W4383619439A5059755817 @default.
- W4383619439 hasAuthorship W4383619439A5085048979 @default.
- W4383619439 hasBestOaLocation W43836194391 @default.
- W4383619439 hasConcept C104317684 @default.
- W4383619439 hasConcept C108625454 @default.
- W4383619439 hasConcept C137610392 @default.
- W4383619439 hasConcept C156534840 @default.
- W4383619439 hasConcept C185592680 @default.
- W4383619439 hasConcept C193244246 @default.
- W4383619439 hasConcept C206212055 @default.
- W4383619439 hasConcept C23123220 @default.
- W4383619439 hasConcept C2777313579 @default.
- W4383619439 hasConcept C41008148 @default.
- W4383619439 hasConcept C41584329 @default.
- W4383619439 hasConcept C48000682 @default.
- W4383619439 hasConcept C501593827 @default.
- W4383619439 hasConcept C55493867 @default.
- W4383619439 hasConcept C70721500 @default.
- W4383619439 hasConcept C77088390 @default.
- W4383619439 hasConcept C86803240 @default.
- W4383619439 hasConcept C97854310 @default.
- W4383619439 hasConceptScore W4383619439C104317684 @default.