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- W4383620565 abstract "Background Serotonin reuptake inhibitors are commonly used for treatment of mental health problems in pregnancy but may cause neonatal adaptation syndrome. It is unknown whether reduction or discontinuation of medication prior to delivery may mitigate this effect. Methods We present a case series of 38 women who either tapered their medication prior to delivery or maintained or increased their dose. Results Greater reductions in maternal antidepressant dose just prior to delivery were associated with fewer admissions to the neonatal intensive care unit (NICU) for infants. There was a slightly greater increase in depressive symptoms across delivery for women who tapered, which was not statistically significant. Conclusions NICU admissions may be less frequent among neonates whose mothers tapered their medication prior to delivery. Large prospective randomized trials are needed to further study this practice." @default.
- W4383620565 created "2023-07-09" @default.
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- W4383620565 date "2023-07-21" @default.
- W4383620565 modified "2023-09-25" @default.
- W4383620565 title "Risks and benefits of pre‐delivery taper in pregnant women taking antidepressants" @default.
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- W4383620565 doi "https://doi.org/10.1111/acps.13593" @default.
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