Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383669912> ?p ?o ?g. }
- W4383669912 endingPage "26" @default.
- W4383669912 startingPage "20" @default.
- W4383669912 abstract "Solid Lipid Nanoparticles (SLNs) have gained significant attention in recent years as a promising delivery system for drugs targeting the Central Nervous System (CNS) via the Nose-To-Brain (NTB) route. The unique characteristics of SLNs, such as their small particle size, high stability, and ability to encapsulate lipophilic drugs, make them suitable for crossing the Blood Brain Barrier (BBB) and achieving targeted delivery to the brain. This has led to the development of SLNs-based formulations of drugs for neurological disorders such as Alzheimer's disease and Parkinson's disease, which are being evaluated in preclinical and clinical studies. Overall, the recent advances in SLN technology have improved these nanoparticles' stability, drug loading capacity and BBB crossing ability, making them a promising delivery system for NTB drug delivery. SLNs are composed of a solid lipid core surrounded by a surfactant coating, which allows for the encapsulation of hydrophilic and hydrophobic drugs. Additionally, we will also highlight the current challenges and future perspectives of using SLNs for NTB delivery of CNS therapeutics. Overall, this review aims to provide a comprehensive overview of the current state of the art in using SLNs for NTB delivery and to encourage further research in this field." @default.
- W4383669912 created "2023-07-09" @default.
- W4383669912 creator A5004232773 @default.
- W4383669912 creator A5042208087 @default.
- W4383669912 creator A5058760841 @default.
- W4383669912 date "2023-07-07" @default.
- W4383669912 modified "2023-09-27" @default.
- W4383669912 title "SOLID LIPID NANOPARTILCES: MODERN PROGRESS IN NOSE-TO-BRAIN TRANSDUCTION" @default.
- W4383669912 cites W111579719 @default.
- W4383669912 cites W1867070834 @default.
- W4383669912 cites W1867774233 @default.
- W4383669912 cites W1964891492 @default.
- W4383669912 cites W1992535564 @default.
- W4383669912 cites W1993908233 @default.
- W4383669912 cites W2001525797 @default.
- W4383669912 cites W2035745039 @default.
- W4383669912 cites W2036794860 @default.
- W4383669912 cites W2044682044 @default.
- W4383669912 cites W2067790699 @default.
- W4383669912 cites W2073700585 @default.
- W4383669912 cites W2080832752 @default.
- W4383669912 cites W2084094166 @default.
- W4383669912 cites W2086626740 @default.
- W4383669912 cites W2101099825 @default.
- W4383669912 cites W2101594367 @default.
- W4383669912 cites W2103649986 @default.
- W4383669912 cites W2148465626 @default.
- W4383669912 cites W2156946852 @default.
- W4383669912 cites W2580700764 @default.
- W4383669912 cites W2721615787 @default.
- W4383669912 cites W2776410906 @default.
- W4383669912 cites W2794171684 @default.
- W4383669912 cites W2801808920 @default.
- W4383669912 cites W2804592477 @default.
- W4383669912 cites W2887204204 @default.
- W4383669912 cites W2898307391 @default.
- W4383669912 cites W2953443960 @default.
- W4383669912 cites W2981157871 @default.
- W4383669912 cites W2990016411 @default.
- W4383669912 cites W3007961792 @default.
- W4383669912 cites W3007997158 @default.
- W4383669912 cites W3023383116 @default.
- W4383669912 cites W3163677112 @default.
- W4383669912 cites W3216813340 @default.
- W4383669912 cites W4206377857 @default.
- W4383669912 cites W4226362622 @default.
- W4383669912 cites W4280546923 @default.
- W4383669912 cites W4320918089 @default.
- W4383669912 doi "https://doi.org/10.22159/ijap.2023v15i4.47897" @default.
- W4383669912 hasPublicationYear "2023" @default.
- W4383669912 type Work @default.
- W4383669912 citedByCount "0" @default.
- W4383669912 crossrefType "journal-article" @default.
- W4383669912 hasAuthorship W4383669912A5004232773 @default.
- W4383669912 hasAuthorship W4383669912A5042208087 @default.
- W4383669912 hasAuthorship W4383669912A5058760841 @default.
- W4383669912 hasBestOaLocation W43836699121 @default.
- W4383669912 hasConcept C126322002 @default.
- W4383669912 hasConcept C126511603 @default.
- W4383669912 hasConcept C171250308 @default.
- W4383669912 hasConcept C192562407 @default.
- W4383669912 hasConcept C199529486 @default.
- W4383669912 hasConcept C2778402981 @default.
- W4383669912 hasConcept C2779820397 @default.
- W4383669912 hasConcept C2780035454 @default.
- W4383669912 hasConcept C2983812674 @default.
- W4383669912 hasConcept C529278444 @default.
- W4383669912 hasConcept C71924100 @default.
- W4383669912 hasConcept C85663871 @default.
- W4383669912 hasConcept C98274493 @default.
- W4383669912 hasConceptScore W4383669912C126322002 @default.
- W4383669912 hasConceptScore W4383669912C126511603 @default.
- W4383669912 hasConceptScore W4383669912C171250308 @default.
- W4383669912 hasConceptScore W4383669912C192562407 @default.
- W4383669912 hasConceptScore W4383669912C199529486 @default.
- W4383669912 hasConceptScore W4383669912C2778402981 @default.
- W4383669912 hasConceptScore W4383669912C2779820397 @default.
- W4383669912 hasConceptScore W4383669912C2780035454 @default.
- W4383669912 hasConceptScore W4383669912C2983812674 @default.
- W4383669912 hasConceptScore W4383669912C529278444 @default.
- W4383669912 hasConceptScore W4383669912C71924100 @default.
- W4383669912 hasConceptScore W4383669912C85663871 @default.
- W4383669912 hasConceptScore W4383669912C98274493 @default.
- W4383669912 hasLocation W43836699121 @default.
- W4383669912 hasOpenAccess W4383669912 @default.
- W4383669912 hasPrimaryLocation W43836699121 @default.
- W4383669912 hasRelatedWork W1603107043 @default.
- W4383669912 hasRelatedWork W2002675502 @default.
- W4383669912 hasRelatedWork W2121883940 @default.
- W4383669912 hasRelatedWork W2284884492 @default.
- W4383669912 hasRelatedWork W2307896665 @default.
- W4383669912 hasRelatedWork W2771690080 @default.
- W4383669912 hasRelatedWork W2800387546 @default.
- W4383669912 hasRelatedWork W2999983612 @default.
- W4383669912 hasRelatedWork W3138364107 @default.
- W4383669912 hasRelatedWork W4200499989 @default.
- W4383669912 isParatext "false" @default.
- W4383669912 isRetracted "false" @default.