Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383669918> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4383669918 endingPage "183" @default.
- W4383669918 startingPage "173" @default.
- W4383669918 abstract "Objective: Boswellia serrata is a plant with a long history of use in traditional medicine, particularly for its anti-inflammatory and anti-cancer properties. Growth factors and their receptors are significant components in the initiation and progression of malignancy, and aberrant functioning of these pathways can result in unrestrained cell division and expansion. Methods: In this study, an in silico approach was used to explore the potential of Boswellia serrata phytochemicals as cancer therapeutics to target growth factor receptors. The virtual screening involved molecular docking simulations (PyRx) to predict the binding affinity between the phytochemicals and the receptors. Results: The seventy-four phytocompounds identified from Boswellia serrata were preliminarily screened based on their binding towards growth factor receptors. The ligands demonstrated better binding with the GFR targets, and the binding score less than-7 kcal/mol was considered for further investigation results demonstrated that Alpha-boswellic exhibited strong binding affinity to the receptors, suggesting their potential as targeted cancer therapies. This study provides a foundation for future in vitro and in vivo experiments to validate the efficacy of these phytochemicals as cancer treatments. Conclusion: The results suggest that Boswellic acid derivatives from Boswellia serrata could be a promising source of new cancer therapies." @default.
- W4383669918 created "2023-07-09" @default.
- W4383669918 creator A5061536984 @default.
- W4383669918 creator A5087536203 @default.
- W4383669918 creator A5092431175 @default.
- W4383669918 creator A5092431176 @default.
- W4383669918 date "2023-07-07" @default.
- W4383669918 modified "2023-09-25" @default.
- W4383669918 title "MOLECULAR DOCKING AND INVESTIGATION OF BOSWELLIA SERRATA PHYTOCOMPOUNDS AS CANCER THERAPEUTICS TO TARGET GROWTH FACTOR RECEPTORS: AN IN SILICO APPROACH" @default.
- W4383669918 cites W1845828573 @default.
- W4383669918 cites W1887624773 @default.
- W4383669918 cites W1912388982 @default.
- W4383669918 cites W2003560690 @default.
- W4383669918 cites W2336608924 @default.
- W4383669918 cites W2600338350 @default.
- W4383669918 cites W2615601352 @default.
- W4383669918 cites W2619163315 @default.
- W4383669918 cites W2620998958 @default.
- W4383669918 cites W2751476102 @default.
- W4383669918 cites W2899070097 @default.
- W4383669918 cites W2939823621 @default.
- W4383669918 cites W2949305189 @default.
- W4383669918 cites W2997368943 @default.
- W4383669918 cites W3096497775 @default.
- W4383669918 cites W3154258817 @default.
- W4383669918 cites W3200159383 @default.
- W4383669918 cites W4206582683 @default.
- W4383669918 cites W4206651078 @default.
- W4383669918 cites W4220781866 @default.
- W4383669918 cites W4291786797 @default.
- W4383669918 cites W4293030504 @default.
- W4383669918 cites W4324124894 @default.
- W4383669918 doi "https://doi.org/10.22159/ijap.2023v15i4.47833" @default.
- W4383669918 hasPublicationYear "2023" @default.
- W4383669918 type Work @default.
- W4383669918 citedByCount "0" @default.
- W4383669918 crossrefType "journal-article" @default.
- W4383669918 hasAuthorship W4383669918A5061536984 @default.
- W4383669918 hasAuthorship W4383669918A5087536203 @default.
- W4383669918 hasAuthorship W4383669918A5092431175 @default.
- W4383669918 hasAuthorship W4383669918A5092431176 @default.
- W4383669918 hasBestOaLocation W43836699181 @default.
- W4383669918 hasConcept C104317684 @default.
- W4383669918 hasConcept C142724271 @default.
- W4383669918 hasConcept C170493617 @default.
- W4383669918 hasConcept C204787440 @default.
- W4383669918 hasConcept C2775905019 @default.
- W4383669918 hasConcept C2780574456 @default.
- W4383669918 hasConcept C41685203 @default.
- W4383669918 hasConcept C42972112 @default.
- W4383669918 hasConcept C55493867 @default.
- W4383669918 hasConcept C556039675 @default.
- W4383669918 hasConcept C71924100 @default.
- W4383669918 hasConcept C86803240 @default.
- W4383669918 hasConcept C98274493 @default.
- W4383669918 hasConceptScore W4383669918C104317684 @default.
- W4383669918 hasConceptScore W4383669918C142724271 @default.
- W4383669918 hasConceptScore W4383669918C170493617 @default.
- W4383669918 hasConceptScore W4383669918C204787440 @default.
- W4383669918 hasConceptScore W4383669918C2775905019 @default.
- W4383669918 hasConceptScore W4383669918C2780574456 @default.
- W4383669918 hasConceptScore W4383669918C41685203 @default.
- W4383669918 hasConceptScore W4383669918C42972112 @default.
- W4383669918 hasConceptScore W4383669918C55493867 @default.
- W4383669918 hasConceptScore W4383669918C556039675 @default.
- W4383669918 hasConceptScore W4383669918C71924100 @default.
- W4383669918 hasConceptScore W4383669918C86803240 @default.
- W4383669918 hasConceptScore W4383669918C98274493 @default.
- W4383669918 hasLocation W43836699181 @default.
- W4383669918 hasOpenAccess W4383669918 @default.
- W4383669918 hasPrimaryLocation W43836699181 @default.
- W4383669918 hasRelatedWork W1983976007 @default.
- W4383669918 hasRelatedWork W213324737 @default.
- W4383669918 hasRelatedWork W2403568753 @default.
- W4383669918 hasRelatedWork W2510906181 @default.
- W4383669918 hasRelatedWork W2852208711 @default.
- W4383669918 hasRelatedWork W2944662550 @default.
- W4383669918 hasRelatedWork W3197696641 @default.
- W4383669918 hasRelatedWork W3198266329 @default.
- W4383669918 hasRelatedWork W4226225960 @default.
- W4383669918 hasRelatedWork W4280591136 @default.
- W4383669918 isParatext "false" @default.
- W4383669918 isRetracted "false" @default.
- W4383669918 workType "article" @default.