Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383682167> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4383682167 endingPage "384" @default.
- W4383682167 startingPage "377" @default.
- W4383682167 abstract "Purpose: This study aimed to investigate the status of DNA polymerase delta (POLD1 and POLD2) gene expression at the time of diagnosis in pediatric acute lymphoblastic leukemia (ALL) patients, compared with the normal population, and its relationship with prognosis and other clinical findings.
 Materials and Methods: Seventy-three patients diagnosed with ALL between January 2008 and November 2015 and 29 healthy control subjects were included in the study. Gene expression profiling of peripheral blood samples was performed using Real-time PCR.
 Results: The mean value of POLD1 gene expression was found to be significantly higher in ALL patients at the time of diagnosis than the control group (376.5± 685.8 and 17.9± 19.8, respectively), but there was no difference in POLD2 gene expression (511.5± 898.1 and 125.4± 132.7, respectively). POLD1 and POLD2 gene expressions were found to be low in patients with relapse and exitus, but the results were not statistically significant. Patients with low levels of POLD1 expression had lower survival rates in the 5th year than those with high levels of expression (54% and 68%, respectively), and similarly, patients with low levels of POLD2 expression had lower survival rates in the 5th year compared to those with high levels of expression (58% and 68%, respectively).
 Conclusion: Lower POLD1 and POLD2 expressions at the time of diagnosis in ALL patients may adversely affects the prognosis." @default.
- W4383682167 created "2023-07-10" @default.
- W4383682167 creator A5021869952 @default.
- W4383682167 creator A5036113170 @default.
- W4383682167 creator A5040986067 @default.
- W4383682167 creator A5048597735 @default.
- W4383682167 creator A5063397014 @default.
- W4383682167 creator A5072253720 @default.
- W4383682167 date "2023-07-02" @default.
- W4383682167 modified "2023-09-25" @default.
- W4383682167 title "DNA polymerase delta (POLD1 and POLD2) gene expression in pediatric acute lymphoblastic leukemia patients and its relationship with prognosis" @default.
- W4383682167 cites W1608038670 @default.
- W4383682167 cites W1639113761 @default.
- W4383682167 cites W1980781636 @default.
- W4383682167 cites W1981519412 @default.
- W4383682167 cites W2046320643 @default.
- W4383682167 cites W2050921758 @default.
- W4383682167 cites W2059999488 @default.
- W4383682167 cites W2145606954 @default.
- W4383682167 cites W2146501164 @default.
- W4383682167 cites W2168581769 @default.
- W4383682167 cites W2252367299 @default.
- W4383682167 cites W2804365853 @default.
- W4383682167 cites W2998146034 @default.
- W4383682167 cites W3098650302 @default.
- W4383682167 cites W3119005666 @default.
- W4383682167 cites W4200452274 @default.
- W4383682167 doi "https://doi.org/10.17826/cumj.1221593" @default.
- W4383682167 hasPublicationYear "2023" @default.
- W4383682167 type Work @default.
- W4383682167 citedByCount "0" @default.
- W4383682167 crossrefType "journal-article" @default.
- W4383682167 hasAuthorship W4383682167A5021869952 @default.
- W4383682167 hasAuthorship W4383682167A5036113170 @default.
- W4383682167 hasAuthorship W4383682167A5040986067 @default.
- W4383682167 hasAuthorship W4383682167A5048597735 @default.
- W4383682167 hasAuthorship W4383682167A5063397014 @default.
- W4383682167 hasAuthorship W4383682167A5072253720 @default.
- W4383682167 hasBestOaLocation W43836821671 @default.
- W4383682167 hasConcept C104317684 @default.
- W4383682167 hasConcept C126322002 @default.
- W4383682167 hasConcept C150194340 @default.
- W4383682167 hasConcept C203014093 @default.
- W4383682167 hasConcept C2756471 @default.
- W4383682167 hasConcept C2778461978 @default.
- W4383682167 hasConcept C2909962599 @default.
- W4383682167 hasConcept C48023723 @default.
- W4383682167 hasConcept C49105822 @default.
- W4383682167 hasConcept C54355233 @default.
- W4383682167 hasConcept C71924100 @default.
- W4383682167 hasConcept C86803240 @default.
- W4383682167 hasConceptScore W4383682167C104317684 @default.
- W4383682167 hasConceptScore W4383682167C126322002 @default.
- W4383682167 hasConceptScore W4383682167C150194340 @default.
- W4383682167 hasConceptScore W4383682167C203014093 @default.
- W4383682167 hasConceptScore W4383682167C2756471 @default.
- W4383682167 hasConceptScore W4383682167C2778461978 @default.
- W4383682167 hasConceptScore W4383682167C2909962599 @default.
- W4383682167 hasConceptScore W4383682167C48023723 @default.
- W4383682167 hasConceptScore W4383682167C49105822 @default.
- W4383682167 hasConceptScore W4383682167C54355233 @default.
- W4383682167 hasConceptScore W4383682167C71924100 @default.
- W4383682167 hasConceptScore W4383682167C86803240 @default.
- W4383682167 hasIssue "2" @default.
- W4383682167 hasLocation W43836821671 @default.
- W4383682167 hasOpenAccess W4383682167 @default.
- W4383682167 hasPrimaryLocation W43836821671 @default.
- W4383682167 hasRelatedWork W1974846613 @default.
- W4383682167 hasRelatedWork W2009966535 @default.
- W4383682167 hasRelatedWork W2012320318 @default.
- W4383682167 hasRelatedWork W2090890953 @default.
- W4383682167 hasRelatedWork W2358052149 @default.
- W4383682167 hasRelatedWork W2381294515 @default.
- W4383682167 hasRelatedWork W2393389982 @default.
- W4383682167 hasRelatedWork W2414933257 @default.
- W4383682167 hasRelatedWork W2754703032 @default.
- W4383682167 hasRelatedWork W332387397 @default.
- W4383682167 hasVolume "48" @default.
- W4383682167 isParatext "false" @default.
- W4383682167 isRetracted "false" @default.
- W4383682167 workType "article" @default.