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- W4383695660 abstract "This narrative review addresses the definition of acute-on-chronic liver failure, a condition associated with high short-term mortality in patients with chronic liver disease and/or cirrhosis. We provide two major points of view: the East and the West perspective. Both definitions vary regarding the underlying patient population and organ failure(s) definition. Nevertheless, all the definitions have their clinical utility: from the core concept of having the liver as a conditio sine qua non, the syndrome cannot exist (Asian Pacific Association for the Study of the Liver); a data-driven, robust definition (European Association for the Study of the Liver); a bedside tool that can quickly identify patients at high risk of dying (North American Consortium for the Study of End-stage Liver Disease [NACSELD]). In each section, we provide the overall definitions, the criteria of organ failure(s), and some epidemiological data illustrating how these apply in each area of the world." @default.
- W4383695660 created "2023-07-10" @default.
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- W4383695660 date "2023-07-09" @default.
- W4383695660 modified "2023-10-18" @default.
- W4383695660 title "Definition, diagnosis and epidemiology of acute‐on‐chronic liver failure" @default.
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- W4383695660 doi "https://doi.org/10.1111/liv.15670" @default.
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