FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383709578> ?p ?o ?g. }

• W4383709578 endingPage "656" @default.
• W4383709578 startingPage "646" @default.
• W4383709578 abstract "Abstract Background Bacterial vaginosis (BV) is a common vaginal dysbiosis that often recurs following first-line antibiotics. We investigated if vaginal microbiota composition was associated with BV recurrence. Methods We analyzed samples and data from 121 women who participated in 3 published trials evaluating novel interventions for improving BV cure, including concurrent antibiotic treatment of regular sexual partners (RSPs). Women diagnosed with BV received first-line antibiotics and self-collected vaginal swabs pretreatment and the day after finishing antibiotics (immediately posttreatment). 16S rRNA gene sequencing was performed on vaginal samples. Logistic regression explored associations between BV recurrence and features of the vaginal microbiota pre- and posttreatment. Results Sixteen women (13% [95% confidence interval {CI}, 8%–21%]) experienced BV recurrence within 1 month of treatment. Women with an untreated RSP were more likely to experience recurrence than women with no RSP (P = .008) or an RSP who received treatment (P = .011). A higher abundance of Prevotella pretreatment (adjusted odds ratio [AOR], 1.35 [95% CI, 1.05–1.91]) and Gardnerella immediately posttreatment (AOR, 1.23 [95% CI, 1.03–1.49]) were associated with increased odds of BV recurrence. Conclusions Having specific Prevotella spp prior to recommended treatment and persistence of Gardnerella immediately posttreatment may contribute to the high rates of BV recurrence. Interventions that target these taxa are likely required to achieve sustained BV cure." @default.
• W4383709578 created "2023-07-11" @default.
• W4383709578 creator A5001915152 @default.
• W4383709578 creator A5008481687 @default.
• W4383709578 creator A5016348158 @default.
• W4383709578 creator A5018081628 @default.
• W4383709578 creator A5019983154 @default.
• W4383709578 creator A5033943773 @default.
• W4383709578 creator A5038324974 @default.
• W4383709578 creator A5045084750 @default.
• W4383709578 creator A5058438440 @default.
• W4383709578 creator A5067622825 @default.
• W4383709578 creator A5092434114 @default.
• W4383709578 date "2023-07-10" @default.
• W4383709578 modified "2023-09-27" @default.
• W4383709578 title "<i>Prevotella</i> and <i>Gardnerella</i> are associated with treatment failure following first-line antibiotics for bacterial vaginosis" @default.
• W4383709578 cites W1919484576 @default.
• W4383709578 cites W1938317057 @default.
• W4383709578 cites W2028783789 @default.
• W4383709578 cites W2033063267 @default.
• W4383709578 cites W2040023115 @default.
• W4383709578 cites W2048712835 @default.
• W4383709578 cites W2058566083 @default.
• W4383709578 cites W2060778814 @default.
• W4383709578 cites W2072409597 @default.
• W4383709578 cites W2105384026 @default.
• W4383709578 cites W2108487398 @default.
• W4383709578 cites W2121997010 @default.
• W4383709578 cites W2136752289 @default.
• W4383709578 cites W2137056037 @default.
• W4383709578 cites W2156518020 @default.
• W4383709578 cites W2158434487 @default.
• W4383709578 cites W2315722591 @default.
• W4383709578 cites W2342627536 @default.
• W4383709578 cites W2526847157 @default.
• W4383709578 cites W2593750454 @default.
• W4383709578 cites W2781959811 @default.
• W4383709578 cites W2909229435 @default.
• W4383709578 cites W2913027027 @default.
• W4383709578 cites W2913269082 @default.
• W4383709578 cites W2920499885 @default.
• W4383709578 cites W2923656803 @default.
• W4383709578 cites W2946458716 @default.
• W4383709578 cites W2952580379 @default.
• W4383709578 cites W2966771290 @default.
• W4383709578 cites W2968872535 @default.
• W4383709578 cites W3014416553 @default.
• W4383709578 cites W3036066733 @default.
• W4383709578 cites W3043062835 @default.
• W4383709578 cites W3044704269 @default.
• W4383709578 cites W3047605696 @default.
• W4383709578 cites W3092399210 @default.
• W4383709578 cites W3107140333 @default.
• W4383709578 cites W3132353187 @default.
• W4383709578 cites W3194617525 @default.
• W4383709578 cites W3197967892 @default.
• W4383709578 cites W3201029957 @default.
• W4383709578 cites W3205311073 @default.
• W4383709578 cites W4206485674 @default.
• W4383709578 cites W4220867181 @default.
• W4383709578 cites W4223593479 @default.
• W4383709578 cites W4225515666 @default.
• W4383709578 cites W4288428126 @default.
• W4383709578 cites W4313530596 @default.
• W4383709578 cites W4313729219 @default.
• W4383709578 cites W4328088926 @default.
• W4383709578 doi "https://doi.org/10.1093/infdis/jiad261" @default.
• W4383709578 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37427495" @default.
• W4383709578 hasPublicationYear "2023" @default.
• W4383709578 type Work @default.
• W4383709578 citedByCount "0" @default.
• W4383709578 crossrefType "journal-article" @default.
• W4383709578 hasAuthorship W4383709578A5001915152 @default.
• W4383709578 hasAuthorship W4383709578A5008481687 @default.
• W4383709578 hasAuthorship W4383709578A5016348158 @default.
• W4383709578 hasAuthorship W4383709578A5018081628 @default.
• W4383709578 hasAuthorship W4383709578A5019983154 @default.
• W4383709578 hasAuthorship W4383709578A5033943773 @default.
• W4383709578 hasAuthorship W4383709578A5038324974 @default.
• W4383709578 hasAuthorship W4383709578A5045084750 @default.
• W4383709578 hasAuthorship W4383709578A5058438440 @default.
• W4383709578 hasAuthorship W4383709578A5067622825 @default.
• W4383709578 hasAuthorship W4383709578A5092434114 @default.
• W4383709578 hasBestOaLocation W43837095781 @default.
• W4383709578 hasConcept C126322002 @default.
• W4383709578 hasConcept C151956035 @default.
• W4383709578 hasConcept C156957248 @default.
• W4383709578 hasConcept C2779952448 @default.
• W4383709578 hasConcept C2780018483 @default.
• W4383709578 hasConcept C2780423288 @default.
• W4383709578 hasConcept C29456083 @default.
• W4383709578 hasConcept C44249647 @default.
• W4383709578 hasConcept C501593827 @default.
• W4383709578 hasConcept C523546767 @default.
• W4383709578 hasConcept C54355233 @default.
• W4383709578 hasConcept C71924100 @default.
• W4383709578 hasConcept C86803240 @default.
• W4383709578 hasConcept C89423630 @default.

• next