FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383709836> ?p ?o ?g. }

• W4383709836 abstract "Coronaviruses (CoVs) are enveloped viruses with a large RNA genome (26 to 32 kb) and are classified into four genera: Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus. CoV infections cause respiratory, enteric, and neurologic disorders in mammalian and avian species. In 2019, Oryx leucoryx animals suffered from severe hemorrhagic diarrhea and high morbidity rates. Upon initial diagnosis, we found that the infected animals were positive for coronavirus by pancoronavirus reverse transcriptase RT-PCR. Next, we detected the presence of CoV particles in these samples by electron microscopy and immunohistochemistry. CoV was isolated and propagated on the HRT-18G cell line, and its full genome was sequenced. Full-genome characterization and amino acid comparisons of this viral agent demonstrated that this virus is an evolutionarily distinct Betacoronavirus belonging to the subgenus Embecovirus and the Betacoronavirus 1 species. Furthermore, we found that it is most similar to the subspecies dromedary camel coronavirus HKU23 by phylogenetic analysis. Here, we present the first report of isolation and characterization of Betacoronavirus associated with enteric disease in Oryx leucoryx.IMPORTANCE CoVs cause enteric and respiratory infections in humans and animal hosts. The ability of CoVs to cross interspecies barriers is well recognized, as emphasized by the ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The identification of novel CoV strains and surveillance of CoVs in both humans and animals are relevant and important to global health. In this study, we isolated and characterized a newly identified Betacoronavirus that causes enteric disease in a wild animal, Oryx leucoryx (the Arabian oryx). This work is the first report describing CoV infection in Oryx leucoryx and provides insights into its origin." @default.
• W4383709836 created "2023-07-11" @default.
• W4383709836 creator A5026422853 @default.
• W4383709836 creator A5026946299 @default.
• W4383709836 creator A5030940796 @default.
• W4383709836 creator A5047545048 @default.
• W4383709836 creator A5053472697 @default.
• W4383709836 creator A5068026702 @default.
• W4383709836 creator A5072437668 @default.
• W4383709836 creator A5083220600 @default.
• W4383709836 creator A5092434126 @default.
• W4383709836 date "2023-08-17" @default.
• W4383709836 modified "2023-09-26" @default.
• W4383709836 title "Identification, Isolation, and Molecular Characterization of <i>Betacoronavirus</i> in <i>Oryx leucoryx</i>" @default.
• W4383709836 cites W1888074064 @default.
• W4383709836 cites W1963991418 @default.
• W4383709836 cites W1965669216 @default.
• W4383709836 cites W1987792444 @default.
• W4383709836 cites W1988425777 @default.
• W4383709836 cites W2002761350 @default.
• W4383709836 cites W2116836732 @default.
• W4383709836 cites W2131988685 @default.
• W4383709836 cites W2147939890 @default.
• W4383709836 cites W2152528032 @default.
• W4383709836 cites W2163400707 @default.
• W4383709836 cites W2227917811 @default.
• W4383709836 cites W2306794997 @default.
• W4383709836 cites W2470646526 @default.
• W4383709836 cites W2471496038 @default.
• W4383709836 cites W2513547424 @default.
• W4383709836 cites W2568183016 @default.
• W4383709836 cites W2593277929 @default.
• W4383709836 cites W2780727857 @default.
• W4383709836 cites W2911284263 @default.
• W4383709836 cites W2912019344 @default.
• W4383709836 cites W2951351373 @default.
• W4383709836 cites W2974693537 @default.
• W4383709836 cites W3001456238 @default.
• W4383709836 cites W3001897055 @default.
• W4383709836 cites W3032597189 @default.
• W4383709836 cites W3074796735 @default.
• W4383709836 cites W3080908108 @default.
• W4383709836 cites W3081018016 @default.
• W4383709836 cites W3091344371 @default.
• W4383709836 cites W311927316 @default.
• W4383709836 cites W3133133483 @default.
• W4383709836 cites W3137162930 @default.
• W4383709836 cites W3149586990 @default.
• W4383709836 cites W3168195479 @default.
• W4383709836 cites W3214432874 @default.
• W4383709836 cites W3217300869 @default.
• W4383709836 cites W41083760 @default.
• W4383709836 cites W4286615985 @default.
• W4383709836 cites W4309797030 @default.
• W4383709836 doi "https://doi.org/10.1128/spectrum.04848-22" @default.
• W4383709836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37428095" @default.
• W4383709836 hasPublicationYear "2023" @default.
• W4383709836 type Work @default.
• W4383709836 citedByCount "0" @default.
• W4383709836 crossrefType "journal-article" @default.
• W4383709836 hasAuthorship W4383709836A5026422853 @default.
• W4383709836 hasAuthorship W4383709836A5026946299 @default.
• W4383709836 hasAuthorship W4383709836A5030940796 @default.
• W4383709836 hasAuthorship W4383709836A5047545048 @default.
• W4383709836 hasAuthorship W4383709836A5053472697 @default.
• W4383709836 hasAuthorship W4383709836A5068026702 @default.
• W4383709836 hasAuthorship W4383709836A5072437668 @default.
• W4383709836 hasAuthorship W4383709836A5083220600 @default.
• W4383709836 hasAuthorship W4383709836A5092434126 @default.
• W4383709836 hasBestOaLocation W43837098361 @default.
• W4383709836 hasConcept C142724271 @default.
• W4383709836 hasConcept C151730666 @default.
• W4383709836 hasConcept C159047783 @default.
• W4383709836 hasConcept C2776844884 @default.
• W4383709836 hasConcept C2777648638 @default.
• W4383709836 hasConcept C2778137277 @default.
• W4383709836 hasConcept C2779134260 @default.
• W4383709836 hasConcept C2779536738 @default.
• W4383709836 hasConcept C3008058167 @default.
• W4383709836 hasConcept C524204448 @default.
• W4383709836 hasConcept C71924100 @default.
• W4383709836 hasConcept C86803240 @default.
• W4383709836 hasConceptScore W4383709836C142724271 @default.
• W4383709836 hasConceptScore W4383709836C151730666 @default.
• W4383709836 hasConceptScore W4383709836C159047783 @default.
• W4383709836 hasConceptScore W4383709836C2776844884 @default.
• W4383709836 hasConceptScore W4383709836C2777648638 @default.
• W4383709836 hasConceptScore W4383709836C2778137277 @default.
• W4383709836 hasConceptScore W4383709836C2779134260 @default.
• W4383709836 hasConceptScore W4383709836C2779536738 @default.
• W4383709836 hasConceptScore W4383709836C3008058167 @default.
• W4383709836 hasConceptScore W4383709836C524204448 @default.
• W4383709836 hasConceptScore W4383709836C71924100 @default.
• W4383709836 hasConceptScore W4383709836C86803240 @default.
• W4383709836 hasIssue "4" @default.
• W4383709836 hasLocation W43837098361 @default.
• W4383709836 hasLocation W43837098362 @default.
• W4383709836 hasLocation W43837098363 @default.
• W4383709836 hasOpenAccess W4383709836 @default.
• W4383709836 hasPrimaryLocation W43837098361 @default.

• next