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- W4383710290 abstract "Abstract Objective To investigate the effect of sodium thiosulfate (STS) on serum calcification factors in patients undergoing maintenance hemodialysis. Methods Forty‐four Patients were randomly divided into control group ( n = 22) and observation group ( n = 22) by envelope method (block 4 randomization). The control group received routine treatment while observation group was treated with STS on the basis of routine treatment. The biochemical indicators, including BUN, UA, SCr, Ca 2+ , P 3− , calcium‐phosphorus product, PTH, hs‐CRP, TG, TC, HDL, LDL, and serum calcification factor MGP, FA, FGF‐23, and OPG levels were compared before and after treatment. Results Control group had no statistically significant difference in the levels of vascular calcification factors MGP, FA, FGF‐23, and OPG before and after treatment ( p > 0.05). Whereas observation group had higher levels of MGP and FA, and lower levels of FGF‐23 and OPG after treatment than before treatment ( p < 0.05). The levels of MGP and FA in observation group were higher than those in control group, and FGF‐23 and OPG were lower than those in control group ( p < 0.05). Conclusion It is speculated that sodium thiosulfate can alleviate the progression of vascular calcification by changing the levels of calcification factors." @default.
- W4383710290 created "2023-07-11" @default.
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- W4383710290 date "2023-07-09" @default.
- W4383710290 modified "2023-10-16" @default.
- W4383710290 title "Effects of sodium thiosulfate on serum calcification factors in patients undergoing maintenance hemodialysis" @default.
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- W4383710290 doi "https://doi.org/10.1111/1744-9987.14029" @default.
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