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• W4383746110 abstract "Our objective was to characterize the incidence, associated clinical factors, timing of infection, microbiology, and incidence of concordant blood culture of urinary tract infections (UTIs) in very low birth weight (VLBW <1,500g) infants. Multicenter observational cohort study of VLBW infants with gestational age (GA) ≤32 weeks, still hospitalized on postnatal day 7, and discharged 2010 to 2018 from Pediatrix Medical Group neonatal intensive care units. Demographic and clinical characteristics of infants with and without UTI were compared. Multivariable logistic regression evaluated adjusted odds of UTI diagnosis. Of 86,492 included infants, 5,988 (7%) had a UTI. The most common pathogen was Enterococcusspp. (20%), followed by Escherichia coli (19%) and Klebsiellaspp. (18%). Candidaspp. (6%) was the most common nonbacterial pathogen. Concordant-positive blood culture was present in 8% of infants with UTI diagnoses. UTI was associated with lower GA, male sex, vaginal delivery, prenatal steroid exposure, and longer duration of hospitalization. UTI is a common cause of infection in VLBW infants, especially among the smallest, most premature, male infants, and those with a longer duration of hospitalization. Neonatal clinicians should consider obtaining urine culture in the setting of late-onset sepsis evaluations in VLBW infants.· UTI is a common cause of LOS in VLBW infants.. · The most common pathogens are Enterococcus spp. and E. coli.. · UTI risk varies among different VLBW infant populations.. · Next steps should include evaluation of preventative measures.." @default.
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• W4383746110 date "2023-07-10" @default.
• W4383746110 modified "2023-10-16" @default.
• W4383746110 title "Urinary Tract Infection Epidemiology in NICUs in the United States" @default.
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• W4383746110 doi "https://doi.org/10.1055/s-0043-1771015" @default.
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• W4383746110 hasPublicationYear "2023" @default.
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