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- W4383816963 abstract "Parasitic infections are one of the major One Health threats in developing countries. Early and accurate diagnosis of the infection is pivotal for the estimate of the disease burden and devising appropriate treatment and control strategies. Parasites are diagnosed by simple conventional tools such as microscopy. Many protozoa, e.g. Babesia, Plasmodium and Trypanosoma, can be detected easily through stained preparation by microscopy. However, even with trained technicians, this tool exhibits lower sensitivity and specificity (may be due to low parasite number). Microscopy along with parasite culturing can improve the issue of low sensitivity and specificity and has been used for the diagnosis of trypanosomiasis and leishmaniasis. Serological tools such as ELISA offer a promising tool but their use alone is associated with increased false results, particularly where antigens from different parasites exhibit cross reactivity. With the advent of molecular biology, other sensitive and specific techniques are being devised for the early detection of different parasitic pathogens. Nowadays, customized approaches of conventional polymerase chain reaction are being developed with improved sensitivity and specificity that can therefore effectively address the problems encountered with traditional diagnostic tools. Moreover, advancements in proteomics and biosensing are offering promising solutions in parasite diagnostics for the near future. This chapter details conventional and advanced tools for parasite diagnosis with case scenarios in the developing world." @default.
- W4383816963 created "2023-07-11" @default.
- W4383816963 creator A5021630243 @default.
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- W4383816963 date "2023-07-10" @default.
- W4383816963 modified "2023-09-25" @default.
- W4383816963 title "Conventional and Molecular Diagnosis of Parasites" @default.
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