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- W4383872388 abstract "Introduction: Nuclear medicine (NM) methods play an important role in the evaluation of renal function in a wide range of clinical indications. The aim of our study was to evaluate the correlation between measured GFR (mGFR) obtained by the three-plasma sample slope-intercept NM method (TPSM) — reference method vs. estimated GFR (eGFR) using Fleming’s single plasma sample method (SPSM) at 120 min, 180 min, and 240 min and correlation of reference method with eGFR with camera-based Gates’ protocol. Material and methods: A total of 82 subjects (33 male/49 female) with a mean age of 54.87 ± 15.65 years were included and mGFR value was obtained by the three-plasma sample slope-intercept NM method and eGFR was obtained with Fleming’s single sample method. eGFR was also quantified with the camera-based Gates’ protocol after i.v. application of [99mTc]Tc-DTPA. Results: Our study revealed a very strong positive significant correlation between all three SPSMs with the TPSM as the reference method. Between the Gates’ method and the TPSM in the group of patients with mGFR ≥ 61–84 mL/min/1.73 m2 and mGFR ≥ 84 mL/min/1.73 m2, a moderate positive statistically significant correlation was obtained. Conclusions: The SPSM method shows a very strong correlation with the reference and low bias in all three groups of patients and can be routinely used for GFR estimation." @default.
- W4383872388 created "2023-07-12" @default.
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- W4383872388 date "2023-02-16" @default.
- W4383872388 modified "2023-10-14" @default.
- W4383872388 title "Comparative analysis of different nuclear medicine techniques in evaluation of renal function" @default.
- W4383872388 doi "https://doi.org/10.5603/nmr.2023.0011" @default.
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