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- W4383873185 abstract "The efficacy of COVID-19 vaccines varies between individuals and populations, and the reasons for this are still not fully understood. Recent clinical studies and animal models have indicated that the gut microbiota may influence the immunogenicity of the vaccine and, thus, its effectiveness. This suggests that there is a bidirectional relationship between the gut microbiota and the COVID-19 vaccine, with the varying components of the microbiota either enhancing or reducing the vaccine’s efficacy. To put an end to the spread of the COVID-19 pandemic, the necessity of vaccines that create powerful and long-term immunity is now more important than ever, and understanding the role of the gut microbiota in this process is essential. Conversely, COVID-19 vaccines also have a significant effect on the gut microbiota, decreasing its total number of organisms and the variety of species present. In this Review, we analyze the evidence that suggesting an interaction between the gut microbiota and COVID-19 vaccine effectiveness, consider the immunological mechanisms that may be responsible for this connection, and explore the possibility of using gut microbiota-focused interventions to improve the efficacy of COVID-19 vaccines." @default.
- W4383873185 created "2023-07-12" @default.
- W4383873185 creator A5016370063 @default.
- W4383873185 creator A5037798401 @default.
- W4383873185 creator A5042731276 @default.
- W4383873185 creator A5047576745 @default.
- W4383873185 creator A5052121797 @default.
- W4383873185 creator A5067693027 @default.
- W4383873185 creator A5090217932 @default.
- W4383873185 date "2023-07-11" @default.
- W4383873185 modified "2023-10-03" @default.
- W4383873185 title "A comprehensive perspective on the interaction between gut microbiota and COVID-19 vaccines" @default.
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