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- W4383877178 abstract "More than 100,000 cleft lip and palate patients have benefited from reconstructive surgeries in Africa because of surgical support from non-governmental organizations such as Smile Train. The Smile Train Express is the largest cleft-centered patient registry with over a million records of clinical records, globally. In this study, we reviewed data from the Eastern African patient registry to analyze and understand the clinical profiles of cleft lip and palate patients operated at Smile Train partner hospitals in East Africa. A cross-sectional study design was undertaken through a retrospective database review in fourteen Eastern African countries. The study population included all patients who had cleft lip and palate surgeries recorded in the Smile Train database between 2001 and 2019. 86,683 patient records from 14 Eastern African countries were included in this study. The mean age was (8.8), the mean weight was 22.3kg and 20.8 kg for males and females, respectively, and 61.9 % of the surgeries were performed on male patients. Left cleft lip and palate (21062, 24.62%) and left cleft lip only (17155, 20.05%) were the most common types of clefts, with bilateral cleft lip only (3958, 4.63%) being the least frequent. complete left cleft lip with complete left alveolus was the most frequent cleft combination observed (n = 21,746) and Cleft lip to cleft lip and palate to cleft palate ratio (CL:CLP: CP) was 4.73:7.1:1. Unilateral primary lip-nose repairs were the most common surgeries (66%). General anesthesia was used for 74,783 (86.2%) of the procedures. Most children with cleft lip and/or palate were underweight, possibly due to malnutrition or related to socioeconomic status. There were more male patients compared to females, which could be related to gender disparities. Access to surgical care for children born with congenital defects needs to be improved, and inequities need to be addressed via more evidence-based collaborative intervention strategies. None" @default.
- W4383877178 created "2023-07-12" @default.
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- W4383877178 date "2023-09-01" @default.
- W4383877178 modified "2023-09-29" @default.
- W4383877178 title "Clinical profiles of individuals with orofacial clefts: Results from fourteen Eastern African countries." @default.
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- W4383877178 doi "https://doi.org/10.1016/j.gpeds.2023.100067" @default.
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