Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383877230> ?p ?o ?g. }
- W4383877230 endingPage "1834" @default.
- W4383877230 startingPage "1820" @default.
- W4383877230 abstract "During immune responses, activating ligands would trigger dynamic spatiotemporal organization of immunoreceptors at the cell interface, governing the fate and effector functions of immune cells. To understand the biophysical mechanisms of immunoreceptor signaling, diverse tools, including DNA technologies, have been developed to manipulate receptor-ligand interactions during the immune activation process. With great capability in the controllable assembly of biomolecules, functional DNA-based precise arrangement of immune molecules at cell interfaces has provided a powerful means in revealing the principles of immunoreceptor triggering, even at the single-molecule level. In addition, precisely regulating immunoreceptor-ligand interactions with functional DNA has been applied in immunotherapies of major diseases. This Perspective will focus on the recent advances in exploring immunoreceptor signaling with functional DNA as the molecular tool as well as the applications of functional DNA mediated regulation of immunoreceptor activation. We also outline the challenges and opportunities of applying functional DNA in immune modulation and immunotherapy." @default.
- W4383877230 created "2023-07-12" @default.
- W4383877230 creator A5002397590 @default.
- W4383877230 creator A5031392990 @default.
- W4383877230 creator A5084452813 @default.
- W4383877230 creator A5088407520 @default.
- W4383877230 date "2023-07-11" @default.
- W4383877230 modified "2023-10-14" @default.
- W4383877230 title "Functional DNA as a Molecular Tool in Regulating Immunoreceptor–Ligand Interactions" @default.
- W4383877230 cites W1521611103 @default.
- W4383877230 cites W1552852054 @default.
- W4383877230 cites W1567090568 @default.
- W4383877230 cites W1963594770 @default.
- W4383877230 cites W1964599873 @default.
- W4383877230 cites W1970510056 @default.
- W4383877230 cites W1974231617 @default.
- W4383877230 cites W1975679096 @default.
- W4383877230 cites W1978073168 @default.
- W4383877230 cites W1981226457 @default.
- W4383877230 cites W1995893035 @default.
- W4383877230 cites W2008662133 @default.
- W4383877230 cites W2011984976 @default.
- W4383877230 cites W2024949907 @default.
- W4383877230 cites W2025454174 @default.
- W4383877230 cites W2034306306 @default.
- W4383877230 cites W2038125628 @default.
- W4383877230 cites W2038156304 @default.
- W4383877230 cites W2040094175 @default.
- W4383877230 cites W2040522878 @default.
- W4383877230 cites W2045692387 @default.
- W4383877230 cites W2046133147 @default.
- W4383877230 cites W2052826004 @default.
- W4383877230 cites W2055567106 @default.
- W4383877230 cites W2063880503 @default.
- W4383877230 cites W2067257663 @default.
- W4383877230 cites W2071423255 @default.
- W4383877230 cites W2072687635 @default.
- W4383877230 cites W2072895616 @default.
- W4383877230 cites W2073883364 @default.
- W4383877230 cites W2077423161 @default.
- W4383877230 cites W2078387056 @default.
- W4383877230 cites W2079321730 @default.
- W4383877230 cites W2080529573 @default.
- W4383877230 cites W2082015621 @default.
- W4383877230 cites W2103409481 @default.
- W4383877230 cites W2103931611 @default.
- W4383877230 cites W2123795937 @default.
- W4383877230 cites W2126201627 @default.
- W4383877230 cites W2126961173 @default.
- W4383877230 cites W2128035403 @default.
- W4383877230 cites W2131055846 @default.
- W4383877230 cites W2157417177 @default.
- W4383877230 cites W2158346543 @default.
- W4383877230 cites W2161686873 @default.
- W4383877230 cites W2216203568 @default.
- W4383877230 cites W2271020365 @default.
- W4383877230 cites W2295087691 @default.
- W4383877230 cites W2332517313 @default.
- W4383877230 cites W2334437992 @default.
- W4383877230 cites W2395845086 @default.
- W4383877230 cites W2560367415 @default.
- W4383877230 cites W2592133876 @default.
- W4383877230 cites W2602990311 @default.
- W4383877230 cites W2725398806 @default.
- W4383877230 cites W2761777466 @default.
- W4383877230 cites W2769722035 @default.
- W4383877230 cites W2782689871 @default.
- W4383877230 cites W2788055013 @default.
- W4383877230 cites W2790023075 @default.
- W4383877230 cites W2799731306 @default.
- W4383877230 cites W2803300773 @default.
- W4383877230 cites W2807748927 @default.
- W4383877230 cites W2808137381 @default.
- W4383877230 cites W2810348271 @default.
- W4383877230 cites W2883593500 @default.
- W4383877230 cites W2884166686 @default.
- W4383877230 cites W2892640821 @default.
- W4383877230 cites W2896517179 @default.
- W4383877230 cites W2898989437 @default.
- W4383877230 cites W2900088368 @default.
- W4383877230 cites W2905330124 @default.
- W4383877230 cites W2911188303 @default.
- W4383877230 cites W2913121738 @default.
- W4383877230 cites W2913753776 @default.
- W4383877230 cites W2928371893 @default.
- W4383877230 cites W2976957583 @default.
- W4383877230 cites W2981818680 @default.
- W4383877230 cites W2988845695 @default.
- W4383877230 cites W2992070886 @default.
- W4383877230 cites W2997853711 @default.
- W4383877230 cites W2998836267 @default.
- W4383877230 cites W2999526344 @default.
- W4383877230 cites W3002509109 @default.
- W4383877230 cites W3012283572 @default.
- W4383877230 cites W3025247294 @default.
- W4383877230 cites W3037346400 @default.
- W4383877230 cites W3045578670 @default.
- W4383877230 cites W3104365880 @default.