FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383890634> ?p ?o ?g. }

• W4383890634 abstract "Alveolar ridge preservation is a surgical technique used to prevent dimensional changes in the alveolar bone by dressing biomaterials in the extraction socket. Recently, a chitosan biphasic calcium phosphate loaded with trichostatin A (CS/BCP/TSA) scaffold was introduced as an excellent bone-regeneration material. This study aimed to explore the biological properties of released trichostatin A (TSA) and evaluate the potential of the CS/BCP/TSA scaffold in preserving the alveolar ridge in a rat tooth extraction model.In vitro biocompatibility, histone deacetylase (HDAC) activity, and osteogenic differentiation of MC3T3-E1 cells were tested. For in vivo studies, the maxillary first molars (M1) of Wistar rats were extracted, and alveolar ridge preservation was performed using a CS/BCP/TSA scaffold or commercial bone graft. Micro-Computed Tomography (micro-CT), polyfluorochrome labeling, and histological analysis were used to evaluate the ridge-preservation ability.The released TSA was cytocompatible. Inhibition of histone deacetylase (HDAC) activity and induction of osteogenic differentiation in MC3T3-E1 cells were confirmed. The socket dressing with the CS/BCP/TSA scaffold showed increased socket bone fill and preserved the buccal and middle aspects of the alveolar ridge compared with the conventional graft. Further analysis of the bone regeneration ability by histomorphometric and histological analyses demonstrated that CS/BCP/TSA showed a significantly higher potential to induce bone formation and complete healing in the extraction socket than the other groups.The CS/BCP/TSA scaffold is a novel candidate for alveolar ridge preservation." @default.
• W4383890634 created "2023-07-12" @default.
• W4383890634 creator A5065803803 @default.
• W4383890634 creator A5070032854 @default.
• W4383890634 creator A5075430725 @default.
• W4383890634 creator A5085474636 @default.
• W4383890634 creator A5090644104 @default.
• W4383890634 date "2023-01-01" @default.
• W4383890634 modified "2023-09-26" @default.
• W4383890634 title "Alveolar ridge preservation in rat tooth extraction model by chitosan-derived epigenetic modulation scaffold" @default.
• W4383890634 cites W1563624749 @default.
• W4383890634 cites W1783616538 @default.
• W4383890634 cites W1973773144 @default.
• W4383890634 cites W2000866416 @default.
• W4383890634 cites W2064894420 @default.
• W4383890634 cites W2066749771 @default.
• W4383890634 cites W2086775219 @default.
• W4383890634 cites W2088553641 @default.
• W4383890634 cites W2091714066 @default.
• W4383890634 cites W2096425957 @default.
• W4383890634 cites W2106207488 @default.
• W4383890634 cites W2135723025 @default.
• W4383890634 cites W2169857970 @default.
• W4383890634 cites W2176038513 @default.
• W4383890634 cites W2289597502 @default.
• W4383890634 cites W2396747981 @default.
• W4383890634 cites W2409278137 @default.
• W4383890634 cites W2551048872 @default.
• W4383890634 cites W2748595523 @default.
• W4383890634 cites W2791707721 @default.
• W4383890634 cites W2885754364 @default.
• W4383890634 cites W2889223713 @default.
• W4383890634 cites W2892850068 @default.
• W4383890634 cites W2904466651 @default.
• W4383890634 cites W2911142443 @default.
• W4383890634 cites W2959655080 @default.
• W4383890634 cites W2969433233 @default.
• W4383890634 cites W2969489243 @default.
• W4383890634 cites W2979073256 @default.
• W4383890634 cites W2985122650 @default.
• W4383890634 cites W2996345398 @default.
• W4383890634 cites W3022445007 @default.
• W4383890634 cites W3025199522 @default.
• W4383890634 cites W3028273546 @default.
• W4383890634 cites W3034738711 @default.
• W4383890634 cites W3038742584 @default.
• W4383890634 cites W3042945677 @default.
• W4383890634 cites W3086092980 @default.
• W4383890634 cites W3088340449 @default.
• W4383890634 cites W3094283997 @default.
• W4383890634 cites W3111586128 @default.
• W4383890634 cites W3128349284 @default.
• W4383890634 cites W3201815837 @default.
• W4383890634 cites W4200488493 @default.
• W4383890634 cites W4200495356 @default.
• W4383890634 cites W4206931709 @default.
• W4383890634 cites W4214579934 @default.
• W4383890634 cites W4221049188 @default.
• W4383890634 cites W4223578623 @default.
• W4383890634 cites W4224238654 @default.
• W4383890634 cites W4225094348 @default.
• W4383890634 cites W4225731027 @default.
• W4383890634 cites W4236183454 @default.
• W4383890634 cites W4247416428 @default.
• W4383890634 cites W4281911086 @default.
• W4383890634 cites W4285098308 @default.
• W4383890634 cites W4286374035 @default.
• W4383890634 cites W4296378204 @default.
• W4383890634 cites W4306149398 @default.
• W4383890634 cites W4376550746 @default.
• W4383890634 cites W66671524 @default.
• W4383890634 doi "https://doi.org/10.2186/jpr.jpr_d_23_00006" @default.
• W4383890634 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37438120" @default.
• W4383890634 hasPublicationYear "2023" @default.
• W4383890634 type Work @default.
• W4383890634 citedByCount "0" @default.
• W4383890634 crossrefType "journal-article" @default.
• W4383890634 hasAuthorship W4383890634A5065803803 @default.
• W4383890634 hasAuthorship W4383890634A5070032854 @default.
• W4383890634 hasAuthorship W4383890634A5075430725 @default.
• W4383890634 hasAuthorship W4383890634A5085474636 @default.
• W4383890634 hasAuthorship W4383890634A5090644104 @default.
• W4383890634 hasBestOaLocation W43838906341 @default.
• W4383890634 hasConcept C104317684 @default.
• W4383890634 hasConcept C136229726 @default.
• W4383890634 hasConcept C141071460 @default.
• W4383890634 hasConcept C151279780 @default.
• W4383890634 hasConcept C172829275 @default.
• W4383890634 hasConcept C185592680 @default.
• W4383890634 hasConcept C199343813 @default.
• W4383890634 hasConcept C2777865847 @default.
• W4383890634 hasConcept C2778305200 @default.
• W4383890634 hasConcept C2781411149 @default.
• W4383890634 hasConcept C55493867 @default.
• W4383890634 hasConcept C64927066 @default.
• W4383890634 hasConcept C71924100 @default.
• W4383890634 hasConcept C89429830 @default.
• W4383890634 hasConceptScore W4383890634C104317684 @default.
• W4383890634 hasConceptScore W4383890634C136229726 @default.
• W4383890634 hasConceptScore W4383890634C141071460 @default.

• next