Matches in SemOpenAlex for { <https://semopenalex.org/work/W4383955031> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W4383955031 endingPage "1070" @default.
- W4383955031 startingPage "1068" @default.
- W4383955031 abstract "Although acyclovir is a key drug for the treatment of herpes infections, a consciousness disorder known as acyclovir encephalopathy is among its side effects. We encountered a patient with encephalopathy and measured the plasma and cerebrospinal fluid concentrations of acyclovir and its toxicologically active metabolite 9-carboxymethoxymethylguanine (CMMG). Before dialysis, cerebrospinal fluid concentrations of acyclovir and CMMG in this patient with a consciousness disorder were approximately 10% and 1%, respectively, of their plasma concentrations. After 3 days of dialysis, plasma CMMG levels decreased to detectable but below quantitative levels (<0.1 μg/mL), resulting in normal consciousness. These results suggest that decreasing plasma CMMG concentration could be one of clinical biomarkers for improving consciousness in patients with encephalopathy associated with acyclovir." @default.
- W4383955031 created "2023-07-12" @default.
- W4383955031 creator A5011425926 @default.
- W4383955031 creator A5013915631 @default.
- W4383955031 creator A5042862907 @default.
- W4383955031 creator A5063924812 @default.
- W4383955031 creator A5063994719 @default.
- W4383955031 creator A5078922881 @default.
- W4383955031 date "2023-11-01" @default.
- W4383955031 modified "2023-10-14" @default.
- W4383955031 title "A decreasing plasma concentration of a toxicologically active metabolite 9-carboxymethoxymethylguanine after dialysis – A potential new clinical biomarker for improving encephalopathy in patients treated with acyclovir" @default.
- W4383955031 cites W1994396236 @default.
- W4383955031 cites W2017205053 @default.
- W4383955031 cites W2025975417 @default.
- W4383955031 cites W2109950770 @default.
- W4383955031 cites W2110116923 @default.
- W4383955031 cites W2119105959 @default.
- W4383955031 cites W2123461911 @default.
- W4383955031 cites W2135390819 @default.
- W4383955031 cites W2155824810 @default.
- W4383955031 cites W2156512870 @default.
- W4383955031 cites W2809057705 @default.
- W4383955031 cites W2845294391 @default.
- W4383955031 cites W2885949128 @default.
- W4383955031 cites W2903787298 @default.
- W4383955031 cites W2908307675 @default.
- W4383955031 cites W2970135091 @default.
- W4383955031 cites W3167618143 @default.
- W4383955031 cites W4205360627 @default.
- W4383955031 cites W4206773948 @default.
- W4383955031 doi "https://doi.org/10.1016/j.jiac.2023.07.001" @default.
- W4383955031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37437659" @default.
- W4383955031 hasPublicationYear "2023" @default.
- W4383955031 type Work @default.
- W4383955031 citedByCount "0" @default.
- W4383955031 crossrefType "journal-article" @default.
- W4383955031 hasAuthorship W4383955031A5011425926 @default.
- W4383955031 hasAuthorship W4383955031A5013915631 @default.
- W4383955031 hasAuthorship W4383955031A5042862907 @default.
- W4383955031 hasAuthorship W4383955031A5063924812 @default.
- W4383955031 hasAuthorship W4383955031A5063994719 @default.
- W4383955031 hasAuthorship W4383955031A5078922881 @default.
- W4383955031 hasConcept C126322002 @default.
- W4383955031 hasConcept C185592680 @default.
- W4383955031 hasConcept C2777477808 @default.
- W4383955031 hasConcept C2778621155 @default.
- W4383955031 hasConcept C2779651940 @default.
- W4383955031 hasConcept C2779978075 @default.
- W4383955031 hasConcept C2781197716 @default.
- W4383955031 hasConcept C3020079912 @default.
- W4383955031 hasConcept C42219234 @default.
- W4383955031 hasConcept C55493867 @default.
- W4383955031 hasConcept C71924100 @default.
- W4383955031 hasConcept C90924648 @default.
- W4383955031 hasConcept C98274493 @default.
- W4383955031 hasConceptScore W4383955031C126322002 @default.
- W4383955031 hasConceptScore W4383955031C185592680 @default.
- W4383955031 hasConceptScore W4383955031C2777477808 @default.
- W4383955031 hasConceptScore W4383955031C2778621155 @default.
- W4383955031 hasConceptScore W4383955031C2779651940 @default.
- W4383955031 hasConceptScore W4383955031C2779978075 @default.
- W4383955031 hasConceptScore W4383955031C2781197716 @default.
- W4383955031 hasConceptScore W4383955031C3020079912 @default.
- W4383955031 hasConceptScore W4383955031C42219234 @default.
- W4383955031 hasConceptScore W4383955031C55493867 @default.
- W4383955031 hasConceptScore W4383955031C71924100 @default.
- W4383955031 hasConceptScore W4383955031C90924648 @default.
- W4383955031 hasConceptScore W4383955031C98274493 @default.
- W4383955031 hasFunder F4320334764 @default.
- W4383955031 hasIssue "11" @default.
- W4383955031 hasLocation W43839550311 @default.
- W4383955031 hasLocation W43839550312 @default.
- W4383955031 hasOpenAccess W4383955031 @default.
- W4383955031 hasPrimaryLocation W43839550311 @default.
- W4383955031 hasRelatedWork W1964759623 @default.
- W4383955031 hasRelatedWork W1978153214 @default.
- W4383955031 hasRelatedWork W2029703736 @default.
- W4383955031 hasRelatedWork W2037414479 @default.
- W4383955031 hasRelatedWork W2043869383 @default.
- W4383955031 hasRelatedWork W2052493351 @default.
- W4383955031 hasRelatedWork W2054424851 @default.
- W4383955031 hasRelatedWork W2141845144 @default.
- W4383955031 hasRelatedWork W2748952813 @default.
- W4383955031 hasRelatedWork W2899084033 @default.
- W4383955031 hasVolume "29" @default.
- W4383955031 isParatext "false" @default.
- W4383955031 isRetracted "false" @default.
- W4383955031 workType "article" @default.