Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384025559> ?p ?o ?g. }
- W4384025559 abstract "Nuclear magnetic resonance (NMR) spectroscopy is a powerful high-resolution tool for characterizing biomacromolecular structure, dynamics, and interactions. However, the lengthy longitudinal relaxation of the nuclear spins significantly extends the total experimental time, especially at high and ultra-high magnetic field strengths. Although longitudinal relaxation-enhanced techniques have sped up data acquisition, their application has been limited by the chemical shift dispersion. Here we combined an evolutionary algorithm and artificial intelligence to design 1H and 15N radio frequency (RF) pulses with variable phase and amplitude that cover significantly broader bandwidths and allow for rapid data acquisition. We re-engineered the basic transverse relaxation optimized spectroscopy experiment and showed that the RF shapes enhance the spectral sensitivity of well-folded proteins up to 180 kDa molecular weight. These RF shapes can be tailored to re-design triple-resonance experiments for accelerating NMR spectroscopy of biomacromolecules at high fields." @default.
- W4384025559 created "2023-07-13" @default.
- W4384025559 creator A5009664013 @default.
- W4384025559 creator A5010328651 @default.
- W4384025559 creator A5029282780 @default.
- W4384025559 date "2023-07-12" @default.
- W4384025559 modified "2023-10-14" @default.
- W4384025559 title "AI-designed NMR spectroscopy RF pulses for fast acquisition at high and ultra-high magnetic fields" @default.
- W4384025559 cites W1519975928 @default.
- W4384025559 cites W1964840468 @default.
- W4384025559 cites W1966197586 @default.
- W4384025559 cites W1978533437 @default.
- W4384025559 cites W1982099224 @default.
- W4384025559 cites W1990675281 @default.
- W4384025559 cites W1994448943 @default.
- W4384025559 cites W2005236666 @default.
- W4384025559 cites W2006198344 @default.
- W4384025559 cites W2009973554 @default.
- W4384025559 cites W2028028087 @default.
- W4384025559 cites W2034766560 @default.
- W4384025559 cites W2055439983 @default.
- W4384025559 cites W2058724374 @default.
- W4384025559 cites W2074295796 @default.
- W4384025559 cites W2084273798 @default.
- W4384025559 cites W2093147577 @default.
- W4384025559 cites W2095074238 @default.
- W4384025559 cites W2113670799 @default.
- W4384025559 cites W2136332525 @default.
- W4384025559 cites W2144176808 @default.
- W4384025559 cites W2147281292 @default.
- W4384025559 cites W2169821755 @default.
- W4384025559 cites W2896251409 @default.
- W4384025559 cites W2915347451 @default.
- W4384025559 cites W2949250147 @default.
- W4384025559 cites W2950849645 @default.
- W4384025559 cites W2971185131 @default.
- W4384025559 cites W3126211499 @default.
- W4384025559 cites W3134740672 @default.
- W4384025559 cites W359203707 @default.
- W4384025559 cites W4210674394 @default.
- W4384025559 cites W4213454768 @default.
- W4384025559 cites W4282582314 @default.
- W4384025559 cites W4285090270 @default.
- W4384025559 cites W4286364680 @default.
- W4384025559 cites W4288704582 @default.
- W4384025559 cites W4289885698 @default.
- W4384025559 cites W4297877990 @default.
- W4384025559 cites W4309883463 @default.
- W4384025559 cites W4322766595 @default.
- W4384025559 cites W49039634 @default.
- W4384025559 doi "https://doi.org/10.1038/s41467-023-39581-4" @default.
- W4384025559 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37438347" @default.
- W4384025559 hasPublicationYear "2023" @default.
- W4384025559 type Work @default.
- W4384025559 citedByCount "0" @default.
- W4384025559 crossrefType "journal-article" @default.
- W4384025559 hasAuthorship W4384025559A5009664013 @default.
- W4384025559 hasAuthorship W4384025559A5010328651 @default.
- W4384025559 hasAuthorship W4384025559A5029282780 @default.
- W4384025559 hasBestOaLocation W43840255591 @default.
- W4384025559 hasConcept C115260700 @default.
- W4384025559 hasConcept C116447816 @default.
- W4384025559 hasConcept C121332964 @default.
- W4384025559 hasConcept C15744967 @default.
- W4384025559 hasConcept C192562407 @default.
- W4384025559 hasConcept C205860874 @default.
- W4384025559 hasConcept C26873012 @default.
- W4384025559 hasConcept C2776029896 @default.
- W4384025559 hasConcept C2778870898 @default.
- W4384025559 hasConcept C30475298 @default.
- W4384025559 hasConcept C32891209 @default.
- W4384025559 hasConcept C41008148 @default.
- W4384025559 hasConcept C46141821 @default.
- W4384025559 hasConcept C62520636 @default.
- W4384025559 hasConcept C66974803 @default.
- W4384025559 hasConcept C74064498 @default.
- W4384025559 hasConcept C76155785 @default.
- W4384025559 hasConcept C77805123 @default.
- W4384025559 hasConceptScore W4384025559C115260700 @default.
- W4384025559 hasConceptScore W4384025559C116447816 @default.
- W4384025559 hasConceptScore W4384025559C121332964 @default.
- W4384025559 hasConceptScore W4384025559C15744967 @default.
- W4384025559 hasConceptScore W4384025559C192562407 @default.
- W4384025559 hasConceptScore W4384025559C205860874 @default.
- W4384025559 hasConceptScore W4384025559C26873012 @default.
- W4384025559 hasConceptScore W4384025559C2776029896 @default.
- W4384025559 hasConceptScore W4384025559C2778870898 @default.
- W4384025559 hasConceptScore W4384025559C30475298 @default.
- W4384025559 hasConceptScore W4384025559C32891209 @default.
- W4384025559 hasConceptScore W4384025559C41008148 @default.
- W4384025559 hasConceptScore W4384025559C46141821 @default.
- W4384025559 hasConceptScore W4384025559C62520636 @default.
- W4384025559 hasConceptScore W4384025559C66974803 @default.
- W4384025559 hasConceptScore W4384025559C74064498 @default.
- W4384025559 hasConceptScore W4384025559C76155785 @default.
- W4384025559 hasConceptScore W4384025559C77805123 @default.
- W4384025559 hasFunder F4320332161 @default.
- W4384025559 hasIssue "1" @default.
- W4384025559 hasLocation W43840255591 @default.
- W4384025559 hasLocation W43840255592 @default.