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- W4384037013 abstract "(1) Background: More than one-third of patients with meningiomas experience at least one seizure during the course of their disease, and in the 20–50% of cases, seizure represents the onset symptom. After surgery, up to 30% of patients continue to have seizures, while others may experience them later; (2) Methods: The study analyzed retrospectively the risk factors for pre-operative seizures in a large cohort of 358 patients who underwent surgery for newly diagnosed brain meningioma; (3) Results: We identified age, peritumor edema, and location as risk factors for seizure at the onset. Patients with seizures differed from patients without seizures for the following characteristics: younger average age, lower pre-operative Karnofsky Performance Status (KPS), location on the convexity, lower Simpson Grade, lower incidence of pre-operative neurological deficits, and higher incidence of pre-operative peritumor edema. After 24 months, 88.2% of patients were classified as Engel class Ia, and no correlation with disease progression was observed; (4) Conclusions: Meningioma-related epilepsy has generally a positive outcome following surgery and it seems not to be linked to disease progression, even if further studies are needed." @default.
- W4384037013 created "2023-07-13" @default.
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- W4384037013 date "2023-07-11" @default.
- W4384037013 modified "2023-09-25" @default.
- W4384037013 title "Meningioma-Related Epilepsy: A Happy Ending?" @default.
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- W4384037013 doi "https://doi.org/10.3390/jpm13071124" @default.
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