Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384119800> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4384119800 endingPage "504" @default.
- W4384119800 startingPage "499" @default.
- W4384119800 abstract "Growth is an important clinical outcome, especially in childhood-onset inflammatory bowel disease (IBD). Prior research has demonstrated growth improvements with infliximab therapy. There are limited studies evaluating whether clinical and growth outcomes in children initiated on the infliximab originator and infliximab biosimilar are similar.This was a single-center retrospective review of patients with IBD, younger than 17 years old, and initiated on the infliximab originator or biosimilar for at least 12 months between April 2016 and February 2021. Propensity score matching was utilized. Laboratory values, disease activity scores, and growth values were collected at baseline (prior to infliximab initiation), 6 months, and 12 months post initiation. Linear mixed models with random intercepts were used to test differences in measures over time and between study groups.There were 113 patients on the originator and 39 patients on a biosimilar who met eligibility criteria. Propensity score methodology identified 37 dyads (1:1 match). Weight, height, and body mass index z scores increased over time (from baseline to 12 months) for both groups ( P < 0.05) and there was a similar rate of change between study groups. Clinical outcomes of lab values (albumin, C-reactive protein, and hemoglobin) and disease activity scoring were similar from baseline to 12 months between study groups.There were similar improvements in growth and clinical outcomes in patients initiated on the infliximab originator compared to an infliximab biosimilar agent. This study adds to the limited research evaluating whether infliximab biosimilars have similar growth outcomes in children with IBD." @default.
- W4384119800 created "2023-07-14" @default.
- W4384119800 creator A5004168081 @default.
- W4384119800 creator A5015142339 @default.
- W4384119800 creator A5023198734 @default.
- W4384119800 creator A5026664491 @default.
- W4384119800 creator A5042296236 @default.
- W4384119800 creator A5061619375 @default.
- W4384119800 creator A5089705412 @default.
- W4384119800 date "2023-09-20" @default.
- W4384119800 modified "2023-10-18" @default.
- W4384119800 title "Similar Growth Outcomes in Children with Inflammatory Bowel Disease Initiated on Infliximab Originator or Biosimilar" @default.
- W4384119800 cites W1996210651 @default.
- W4384119800 cites W2019804961 @default.
- W4384119800 cites W2020195242 @default.
- W4384119800 cites W2034524595 @default.
- W4384119800 cites W2035863637 @default.
- W4384119800 cites W2049580289 @default.
- W4384119800 cites W2077106621 @default.
- W4384119800 cites W2089327676 @default.
- W4384119800 cites W2090685459 @default.
- W4384119800 cites W2110060698 @default.
- W4384119800 cites W2131346643 @default.
- W4384119800 cites W2144472014 @default.
- W4384119800 cites W2153881101 @default.
- W4384119800 cites W2321453230 @default.
- W4384119800 cites W2330344211 @default.
- W4384119800 cites W2519636089 @default.
- W4384119800 cites W2595773195 @default.
- W4384119800 cites W2598864494 @default.
- W4384119800 cites W2763577621 @default.
- W4384119800 cites W2912610515 @default.
- W4384119800 cites W2912953799 @default.
- W4384119800 cites W2923675504 @default.
- W4384119800 cites W2974665407 @default.
- W4384119800 cites W2986917630 @default.
- W4384119800 cites W3047235224 @default.
- W4384119800 cites W3093633730 @default.
- W4384119800 cites W3096200735 @default.
- W4384119800 cites W3108986256 @default.
- W4384119800 cites W3165670221 @default.
- W4384119800 cites W4211167126 @default.
- W4384119800 cites W4224287010 @default.
- W4384119800 cites W4318927163 @default.
- W4384119800 cites W4321768340 @default.
- W4384119800 doi "https://doi.org/10.1097/mpg.0000000000003890" @default.
- W4384119800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37439588" @default.
- W4384119800 hasPublicationYear "2023" @default.
- W4384119800 type Work @default.
- W4384119800 citedByCount "0" @default.
- W4384119800 crossrefType "journal-article" @default.
- W4384119800 hasAuthorship W4384119800A5004168081 @default.
- W4384119800 hasAuthorship W4384119800A5015142339 @default.
- W4384119800 hasAuthorship W4384119800A5023198734 @default.
- W4384119800 hasAuthorship W4384119800A5026664491 @default.
- W4384119800 hasAuthorship W4384119800A5042296236 @default.
- W4384119800 hasAuthorship W4384119800A5061619375 @default.
- W4384119800 hasAuthorship W4384119800A5089705412 @default.
- W4384119800 hasConcept C126322002 @default.
- W4384119800 hasConcept C167135981 @default.
- W4384119800 hasConcept C17923572 @default.
- W4384119800 hasConcept C197934379 @default.
- W4384119800 hasConcept C2777138892 @default.
- W4384119800 hasConcept C2778260677 @default.
- W4384119800 hasConcept C2779134260 @default.
- W4384119800 hasConcept C59491497 @default.
- W4384119800 hasConcept C71924100 @default.
- W4384119800 hasConceptScore W4384119800C126322002 @default.
- W4384119800 hasConceptScore W4384119800C167135981 @default.
- W4384119800 hasConceptScore W4384119800C17923572 @default.
- W4384119800 hasConceptScore W4384119800C197934379 @default.
- W4384119800 hasConceptScore W4384119800C2777138892 @default.
- W4384119800 hasConceptScore W4384119800C2778260677 @default.
- W4384119800 hasConceptScore W4384119800C2779134260 @default.
- W4384119800 hasConceptScore W4384119800C59491497 @default.
- W4384119800 hasConceptScore W4384119800C71924100 @default.
- W4384119800 hasIssue "4" @default.
- W4384119800 hasLocation W43841198001 @default.
- W4384119800 hasLocation W43841198002 @default.
- W4384119800 hasOpenAccess W4384119800 @default.
- W4384119800 hasPrimaryLocation W43841198001 @default.
- W4384119800 hasRelatedWork W1981336058 @default.
- W4384119800 hasRelatedWork W2587157414 @default.
- W4384119800 hasRelatedWork W2774189845 @default.
- W4384119800 hasRelatedWork W2914211697 @default.
- W4384119800 hasRelatedWork W2914532353 @default.
- W4384119800 hasRelatedWork W2924476097 @default.
- W4384119800 hasRelatedWork W3010465489 @default.
- W4384119800 hasRelatedWork W4220693647 @default.
- W4384119800 hasRelatedWork W4229777120 @default.
- W4384119800 hasRelatedWork W4385064586 @default.
- W4384119800 hasVolume "77" @default.
- W4384119800 isParatext "false" @default.
- W4384119800 isRetracted "false" @default.
- W4384119800 workType "article" @default.