FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384132205> ?p ?o ?g. }

• W4384132205 endingPage "1466" @default.
• W4384132205 startingPage "1458" @default.
• W4384132205 abstract "Previous studies have reported conflicting results of prolonged antibiotic prophylaxis on infectious complications after pancreatoduodenectomy. This study evaluated the effect of prolonged antibiotics on surgical-site infections (SSIs) after pancreatoduodenectomy.A systematic review and meta-analysis was undertaken of SSIs in patients with perioperative (within 24 h) versus prolonged antibiotic (over 24 h) prophylaxis after pancreatoduodenectomy. SSIs were classified as organ/space infections or superficial SSI within 30 days after surgery. ORs were calculated using a Mantel-Haenszel fixed-effect model.Ten studies were included in the qualitative analysis, of which 8 reporting on 1170 patients were included in the quantitative analysis. The duration of prolonged antibiotic prophylaxis varied between 2 and 10 days after surgery. Four studies reporting on 782 patients showed comparable organ/space infection rates in patients receiving perioperative and prolonged antibiotics (OR 1.35, 95 per cent c.i. 0.94 to 1.93). However, among patients with preoperative biliary drainage (5 studies reporting on 577 patients), organ/space infection rates were lower with prolonged compared with perioperative antibiotics (OR 2.09, 1.43 to 3.07). Three studies (633 patients) demonstrated comparable superficial SSI rates between patients receiving perioperative versus prolonged prophylaxis (OR 1.54, 0.97 to 2.44), as well as in patients with preoperative biliary drainage in 4 studies reporting on 431 patients (OR 1.60, 0.89 to 2.88).Prolonged antibiotic prophylaxis is associated with fewer organ/space infection in patients who undergo preoperative biliary drainage. However, the optimal duration of antibiotic prophylaxis after pancreatoduodenectomy remains to be determined and warrants confirmation in an RCT.Almost 40 in 100 patients develop an infection after pancreatic surgery. This study collected research that studied the effect of prolonged antibiotics after pancreatic surgery on the number of infections after surgery. Research articles were selected if patients who received antibiotics only during surgery were compared with those who had prolonged antibiotics after surgery. Prolonged antibiotics means antibiotics for longer than 24 h after surgery. Comparing patients who had antibiotics during surgery and those who received prolonged antibiotics after surgery, this study focused on the number of abdominal infections and wound infections. Ten studies were selected, and these studies included 1170 patients in total. The duration of prolonged antibiotics ranged from 2 to 5 days after pancreatic surgery. Four studies (with 782 patients) showed comparable abdominal infections in patients who had antibiotics only during surgery and those who had prolonged antibiotics after surgery (OR 1.35, 95 per cent c.i. 0.94 to 1.93). However, for patients with a stent in the bile duct (5 studies on 577 patients), fewer abdominal infections were seen in patients who had prolonged antibiotics after surgery compared with patients who received antibiotics only during surgery (OR 2.09, 1.43 to 3.07). Three studies (633 patients) showed the same rate of wound infections in patients who had antibiotics only during surgery compared with those who received prolonged antibiotics after operation (OR 1.54, 0.97 to 2.44). The number of wound infections was also the same in patients with a stent in the bile duct (OR 1.60, 0.89 to 2.88). Prolonged antibiotics after pancreatic surgery seem to lower abdominal infections in patients who have a stent placed in the bile duct. However, the best duration of antibiotics is unclear; a decent study is needed." @default.
• W4384132205 created "2023-07-14" @default.
• W4384132205 creator A5006641161 @default.
• W4384132205 creator A5009834418 @default.
• W4384132205 creator A5021939051 @default.
• W4384132205 creator A5024409239 @default.
• W4384132205 creator A5028075025 @default.
• W4384132205 creator A5052876669 @default.
• W4384132205 creator A5055690884 @default.
• W4384132205 creator A5063019493 @default.
• W4384132205 creator A5073613763 @default.
• W4384132205 creator A5083808912 @default.
• W4384132205 creator A5086117338 @default.
• W4384132205 date "2023-07-13" @default.
• W4384132205 modified "2023-10-13" @default.
• W4384132205 title "Prolonged antibiotic prophylaxis after pancreatoduodenectomy: systematic review and meta-analysis" @default.
• W4384132205 cites W1904634031 @default.
• W4384132205 cites W2044352238 @default.
• W4384132205 cites W2045813056 @default.
• W4384132205 cites W2064239375 @default.
• W4384132205 cites W2064456974 @default.
• W4384132205 cites W2071218337 @default.
• W4384132205 cites W2072857857 @default.
• W4384132205 cites W2087151300 @default.
• W4384132205 cites W2098923148 @default.
• W4384132205 cites W2111911163 @default.
• W4384132205 cites W2156098321 @default.
• W4384132205 cites W2166004106 @default.
• W4384132205 cites W2321288747 @default.
• W4384132205 cites W2405818325 @default.
• W4384132205 cites W2531269403 @default.
• W4384132205 cites W2553674517 @default.
• W4384132205 cites W2565595087 @default.
• W4384132205 cites W2588681363 @default.
• W4384132205 cites W2592760710 @default.
• W4384132205 cites W2602429664 @default.
• W4384132205 cites W2625855903 @default.
• W4384132205 cites W2735606454 @default.
• W4384132205 cites W2805656290 @default.
• W4384132205 cites W2890673239 @default.
• W4384132205 cites W2891173600 @default.
• W4384132205 cites W2950610447 @default.
• W4384132205 cites W2961707645 @default.
• W4384132205 cites W2965396623 @default.
• W4384132205 cites W2967450000 @default.
• W4384132205 cites W2979645343 @default.
• W4384132205 cites W2991792334 @default.
• W4384132205 cites W3011029603 @default.
• W4384132205 cites W3021811194 @default.
• W4384132205 cites W3024247247 @default.
• W4384132205 cites W3032900507 @default.
• W4384132205 cites W3039309678 @default.
• W4384132205 cites W3088318282 @default.
• W4384132205 cites W3110921063 @default.
• W4384132205 cites W3130297146 @default.
• W4384132205 cites W4210531178 @default.
• W4384132205 cites W4211102457 @default.
• W4384132205 cites W4285015072 @default.
• W4384132205 cites W4293393007 @default.
• W4384132205 cites W4307748860 @default.
• W4384132205 cites W4376878890 @default.
• W4384132205 doi "https://doi.org/10.1093/bjs/znad213" @default.
• W4384132205 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37440361" @default.
• W4384132205 hasPublicationYear "2023" @default.
• W4384132205 type Work @default.
• W4384132205 citedByCount "0" @default.
• W4384132205 crossrefType "journal-article" @default.
• W4384132205 hasAuthorship W4384132205A5006641161 @default.
• W4384132205 hasAuthorship W4384132205A5009834418 @default.
• W4384132205 hasAuthorship W4384132205A5021939051 @default.
• W4384132205 hasAuthorship W4384132205A5024409239 @default.
• W4384132205 hasAuthorship W4384132205A5028075025 @default.
• W4384132205 hasAuthorship W4384132205A5052876669 @default.
• W4384132205 hasAuthorship W4384132205A5055690884 @default.
• W4384132205 hasAuthorship W4384132205A5063019493 @default.
• W4384132205 hasAuthorship W4384132205A5073613763 @default.
• W4384132205 hasAuthorship W4384132205A5083808912 @default.
• W4384132205 hasAuthorship W4384132205A5086117338 @default.
• W4384132205 hasBestOaLocation W43841322051 @default.
• W4384132205 hasConcept C126322002 @default.
• W4384132205 hasConcept C141071460 @default.
• W4384132205 hasConcept C2778602436 @default.
• W4384132205 hasConcept C31174226 @default.
• W4384132205 hasConcept C501593827 @default.
• W4384132205 hasConcept C71924100 @default.
• W4384132205 hasConcept C86803240 @default.
• W4384132205 hasConcept C89423630 @default.
• W4384132205 hasConcept C95190672 @default.
• W4384132205 hasConceptScore W4384132205C126322002 @default.
• W4384132205 hasConceptScore W4384132205C141071460 @default.
• W4384132205 hasConceptScore W4384132205C2778602436 @default.
• W4384132205 hasConceptScore W4384132205C31174226 @default.
• W4384132205 hasConceptScore W4384132205C501593827 @default.
• W4384132205 hasConceptScore W4384132205C71924100 @default.
• W4384132205 hasConceptScore W4384132205C86803240 @default.
• W4384132205 hasConceptScore W4384132205C89423630 @default.
• W4384132205 hasConceptScore W4384132205C95190672 @default.
• W4384132205 hasIssue "11" @default.

• next