Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384132623> ?p ?o ?g. }
- W4384132623 endingPage "2023" @default.
- W4384132623 startingPage "00226" @default.
- W4384132623 abstract "Background Right ventricular (RV) diastolic dysfunction may be prognostic in pulmonary hypertension (PH). However, its assessment is complex and relies on conductance catheterisation. We aimed to evaluate echocardiography-based parameters as surrogates of RV diastolic function, provide validation against the gold standard, end-diastolic elastance (Eed), and define the prognostic impact of echocardiography-derived RV diastolic dysfunction. Methods Patients with suspected PH who underwent right heart catheterisation including conductance catheterisation were prospectively recruited. In this study population, an echocardiography-based RV diastolic function surrogate was derived. Survival analyses were performed in patients with precapillary PH in the Giessen PH Registry, with external validation in patients with pulmonary arterial hypertension at Sapienza University (Rome). Results In the derivation cohort (n=61), the early/late diastolic tricuspid inflow velocity ratio (E/A) and early tricuspid inflow velocity/early diastolic tricuspid annular velocity ratio (E/e′) did not correlate with Eed (p>0.05). Receiver operating characteristic analysis revealed a large area under the curve (AUC) for the peak lateral tricuspid annulus systolic velocity/right atrial area index ratio (S′/RAAi) to detect elevated Eed (AUC 0.913, 95% confidence interval (CI) 0.839–0.986) and elevated end-diastolic pressure (AUC 0.848, 95% CI 0.699–0.998) with an optimal threshold of 0.81 m 2 ·s −1 ·cm −1 . Subgroup analyses demonstrated a large AUC in patients with preserved RV systolic function (AUC 0.963, 95% CI 0.882–1.000). Survival analyses confirmed the prognostic relevance of S′/RAAi in the Giessen PH Registry (n=225) and the external validation cohort (n=106). Conclusions Our study demonstrates the usefulness of echocardiography-derived S′/RAAi for noninvasive assessment of RV diastolic function and prognosis in PH." @default.
- W4384132623 created "2023-07-14" @default.
- W4384132623 creator A5007433986 @default.
- W4384132623 creator A5007480230 @default.
- W4384132623 creator A5007818536 @default.
- W4384132623 creator A5013334062 @default.
- W4384132623 creator A5016511599 @default.
- W4384132623 creator A5018972286 @default.
- W4384132623 creator A5034717596 @default.
- W4384132623 creator A5050556570 @default.
- W4384132623 creator A5051202449 @default.
- W4384132623 creator A5067851374 @default.
- W4384132623 creator A5078692650 @default.
- W4384132623 creator A5080618703 @default.
- W4384132623 creator A5083660750 @default.
- W4384132623 creator A5083839456 @default.
- W4384132623 creator A5083890566 @default.
- W4384132623 creator A5089805285 @default.
- W4384132623 creator A5090409167 @default.
- W4384132623 date "2023-07-13" @default.
- W4384132623 modified "2023-09-23" @default.
- W4384132623 title "Echocardiographic evaluation of right ventricular diastolic function in pulmonary hypertension" @default.
- W4384132623 cites W1866413456 @default.
- W4384132623 cites W2005815716 @default.
- W4384132623 cites W2014671408 @default.
- W4384132623 cites W2023314610 @default.
- W4384132623 cites W2025954605 @default.
- W4384132623 cites W2053195746 @default.
- W4384132623 cites W2098328413 @default.
- W4384132623 cites W2122979079 @default.
- W4384132623 cites W2123705106 @default.
- W4384132623 cites W2124624517 @default.
- W4384132623 cites W2127994875 @default.
- W4384132623 cites W2135478059 @default.
- W4384132623 cites W2141227221 @default.
- W4384132623 cites W2144754816 @default.
- W4384132623 cites W2283654658 @default.
- W4384132623 cites W2313186535 @default.
- W4384132623 cites W2492271954 @default.
- W4384132623 cites W2547828373 @default.
- W4384132623 cites W2587782289 @default.
- W4384132623 cites W2794994075 @default.
- W4384132623 cites W2808032701 @default.
- W4384132623 cites W2894839648 @default.
- W4384132623 cites W2901518538 @default.
- W4384132623 cites W2904654692 @default.
- W4384132623 cites W2921565358 @default.
- W4384132623 cites W2936013991 @default.
- W4384132623 cites W2943201974 @default.
- W4384132623 cites W2960772337 @default.
- W4384132623 cites W2972579749 @default.
- W4384132623 cites W2972906304 @default.
- W4384132623 cites W2973393750 @default.
- W4384132623 cites W2990639809 @default.
- W4384132623 cites W3023339611 @default.
- W4384132623 cites W3033194232 @default.
- W4384132623 cites W3095316680 @default.
- W4384132623 cites W3139879442 @default.
- W4384132623 cites W3207081941 @default.
- W4384132623 cites W3211489052 @default.
- W4384132623 cites W3214662122 @default.
- W4384132623 cites W4293217384 @default.
- W4384132623 cites W4295647953 @default.
- W4384132623 cites W4309862459 @default.
- W4384132623 cites W4311361620 @default.
- W4384132623 cites W4377094783 @default.
- W4384132623 doi "https://doi.org/10.1183/23120541.00226-2023" @default.
- W4384132623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37727674" @default.
- W4384132623 hasPublicationYear "2023" @default.
- W4384132623 type Work @default.
- W4384132623 citedByCount "0" @default.
- W4384132623 crossrefType "journal-article" @default.
- W4384132623 hasAuthorship W4384132623A5007433986 @default.
- W4384132623 hasAuthorship W4384132623A5007480230 @default.
- W4384132623 hasAuthorship W4384132623A5007818536 @default.
- W4384132623 hasAuthorship W4384132623A5013334062 @default.
- W4384132623 hasAuthorship W4384132623A5016511599 @default.
- W4384132623 hasAuthorship W4384132623A5018972286 @default.
- W4384132623 hasAuthorship W4384132623A5034717596 @default.
- W4384132623 hasAuthorship W4384132623A5050556570 @default.
- W4384132623 hasAuthorship W4384132623A5051202449 @default.
- W4384132623 hasAuthorship W4384132623A5067851374 @default.
- W4384132623 hasAuthorship W4384132623A5078692650 @default.
- W4384132623 hasAuthorship W4384132623A5080618703 @default.
- W4384132623 hasAuthorship W4384132623A5083660750 @default.
- W4384132623 hasAuthorship W4384132623A5083839456 @default.
- W4384132623 hasAuthorship W4384132623A5083890566 @default.
- W4384132623 hasAuthorship W4384132623A5089805285 @default.
- W4384132623 hasAuthorship W4384132623A5090409167 @default.
- W4384132623 hasBestOaLocation W43841326231 @default.
- W4384132623 hasConcept C126322002 @default.
- W4384132623 hasConcept C164705383 @default.
- W4384132623 hasConcept C2780930700 @default.
- W4384132623 hasConcept C2908647359 @default.
- W4384132623 hasConcept C44249647 @default.
- W4384132623 hasConcept C57900726 @default.
- W4384132623 hasConcept C58471807 @default.
- W4384132623 hasConcept C71924100 @default.