Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384133075> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4384133075 endingPage "144" @default.
- W4384133075 startingPage "141" @default.
- W4384133075 abstract "We aimed to evaluate the prevalence and characteristics of people living with HIV (PLWH) eligible for the long-acting injectable (LAI) regimen with cabotegravir (CAB) and rilpivirine (RPV), in comparison with ineligible individuals. This was an observational, cross-sectional study from the ARCA cohort, including virologically suppressed PLWH with at least one genotypic resistance testing (GRT) for reverse transcriptase and integrase from plasma and/or PBMCs. Eligibility criteria for LAI CAB+RPV were: negative HBsAg, absence of previous virological failures and/or resistance-associated mutations for NNRTIs and/or INSTIs. Potential differences between eligible and ineligible individuals were investigated by univariable and multivariable analyses. 514 individuals were included: 377 (73.3%) were male, median age was 51 (IQR: 43-58), on ART for 9 years (IQR: 4-17), virologically suppressed for 63 months (IQR: 35-105). Eligible individuals for CAB+RPV were 229 (44.5%, 95%CI: 40.8-48.8); compared to ineligible individuals, they received a lower number of previous regimens (aOR 0.76, 95% CI 0.71-0.83, p<0.001) and were on current NNRTIs (aOR 2.16, 95% CI 1.38-3.37, p=0.001). Less than half of virologically suppressed PLWH in the ARCA cohort were potentially eligible for CAB+RPV. They seem to be “less complicated” with shorter exposure to ART and preferably already on NNRTIs." @default.
- W4384133075 created "2023-07-14" @default.
- W4384133075 creator A5015006843 @default.
- W4384133075 creator A5039626143 @default.
- W4384133075 creator A5041572390 @default.
- W4384133075 creator A5042226875 @default.
- W4384133075 creator A5045494329 @default.
- W4384133075 creator A5047438814 @default.
- W4384133075 creator A5049398766 @default.
- W4384133075 creator A5053423077 @default.
- W4384133075 creator A5059232573 @default.
- W4384133075 creator A5061040356 @default.
- W4384133075 creator A5064436457 @default.
- W4384133075 creator A5068695530 @default.
- W4384133075 creator A5081816753 @default.
- W4384133075 creator A5082578432 @default.
- W4384133075 creator A5089689442 @default.
- W4384133075 date "2023-09-01" @default.
- W4384133075 modified "2023-10-14" @default.
- W4384133075 title "Long-acting combination of cabotegravir plus rilpivirine: A picture of potential eligible and ineligible HIV-positive individuals from the Italian ARCA cohort" @default.
- W4384133075 cites W2735497859 @default.
- W4384133075 cites W2809138877 @default.
- W4384133075 cites W3137565606 @default.
- W4384133075 cites W3161601582 @default.
- W4384133075 cites W4381470336 @default.
- W4384133075 doi "https://doi.org/10.1016/j.jgar.2023.07.006" @default.
- W4384133075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37453495" @default.
- W4384133075 hasPublicationYear "2023" @default.
- W4384133075 type Work @default.
- W4384133075 citedByCount "0" @default.
- W4384133075 crossrefType "journal-article" @default.
- W4384133075 hasAuthorship W4384133075A5015006843 @default.
- W4384133075 hasAuthorship W4384133075A5039626143 @default.
- W4384133075 hasAuthorship W4384133075A5041572390 @default.
- W4384133075 hasAuthorship W4384133075A5042226875 @default.
- W4384133075 hasAuthorship W4384133075A5045494329 @default.
- W4384133075 hasAuthorship W4384133075A5047438814 @default.
- W4384133075 hasAuthorship W4384133075A5049398766 @default.
- W4384133075 hasAuthorship W4384133075A5053423077 @default.
- W4384133075 hasAuthorship W4384133075A5059232573 @default.
- W4384133075 hasAuthorship W4384133075A5061040356 @default.
- W4384133075 hasAuthorship W4384133075A5064436457 @default.
- W4384133075 hasAuthorship W4384133075A5068695530 @default.
- W4384133075 hasAuthorship W4384133075A5081816753 @default.
- W4384133075 hasAuthorship W4384133075A5082578432 @default.
- W4384133075 hasAuthorship W4384133075A5089689442 @default.
- W4384133075 hasBestOaLocation W43841330751 @default.
- W4384133075 hasConcept C126322002 @default.
- W4384133075 hasConcept C142462285 @default.
- W4384133075 hasConcept C159047783 @default.
- W4384133075 hasConcept C201903717 @default.
- W4384133075 hasConcept C2778723075 @default.
- W4384133075 hasConcept C2779502633 @default.
- W4384133075 hasConcept C2781413609 @default.
- W4384133075 hasConcept C2993143319 @default.
- W4384133075 hasConcept C3013748606 @default.
- W4384133075 hasConcept C71924100 @default.
- W4384133075 hasConcept C72563966 @default.
- W4384133075 hasConceptScore W4384133075C126322002 @default.
- W4384133075 hasConceptScore W4384133075C142462285 @default.
- W4384133075 hasConceptScore W4384133075C159047783 @default.
- W4384133075 hasConceptScore W4384133075C201903717 @default.
- W4384133075 hasConceptScore W4384133075C2778723075 @default.
- W4384133075 hasConceptScore W4384133075C2779502633 @default.
- W4384133075 hasConceptScore W4384133075C2781413609 @default.
- W4384133075 hasConceptScore W4384133075C2993143319 @default.
- W4384133075 hasConceptScore W4384133075C3013748606 @default.
- W4384133075 hasConceptScore W4384133075C71924100 @default.
- W4384133075 hasConceptScore W4384133075C72563966 @default.
- W4384133075 hasLocation W43841330751 @default.
- W4384133075 hasLocation W43841330752 @default.
- W4384133075 hasOpenAccess W4384133075 @default.
- W4384133075 hasPrimaryLocation W43841330751 @default.
- W4384133075 hasRelatedWork W2754471202 @default.
- W4384133075 hasRelatedWork W2781681713 @default.
- W4384133075 hasRelatedWork W2804705496 @default.
- W4384133075 hasRelatedWork W2870214355 @default.
- W4384133075 hasRelatedWork W2899687620 @default.
- W4384133075 hasRelatedWork W2900399017 @default.
- W4384133075 hasRelatedWork W2959367164 @default.
- W4384133075 hasRelatedWork W2977501643 @default.
- W4384133075 hasRelatedWork W3043617471 @default.
- W4384133075 hasRelatedWork W4319262891 @default.
- W4384133075 hasVolume "34" @default.
- W4384133075 isParatext "false" @default.
- W4384133075 isRetracted "false" @default.
- W4384133075 workType "article" @default.