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- W4384153530 abstract "Non-invasive transcutaneous vagus nerve stimulation elicits similar therapeutic effects as invasive vagus nerve stimulation, offering a potential treatment alternative for a wide range of diseases, including epilepsy. Here, we present a novel, non-invasive stimulation of the vagus nerve, which is performed manually viscero-osteopathically on the abdomen (voVNS). We explore the impact of short-term voVNS on various local and global characteristics of EEG-derived, large-scale evolving functional brain networks from a group of 20 subjects with and without epilepsy. We observe differential voVNS-mediated alterations of these characteristics that can be interpreted as a reconfiguration and modification of networks and their stability and robustness properties. Clearly, future studies are necessary to assess the impact of such a non-pharmaceutical intervention on clinical decision-making in the treatment of epilepsy. However, our findings may add to the current discussion on the importance of the gut-brain axis in health and disease. Clinical Trial Registration : https://drks.de/search/en/trial/DRKS00029914 , identifier DRKS00029914" @default.
- W4384153530 created "2023-07-14" @default.
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- W4384153530 date "2023-07-13" @default.
- W4384153530 modified "2023-09-25" @default.
- W4384153530 title "Modifying functional brain networks in focal epilepsy by manual visceral-osteopathic stimulation of the vagus nerve at the abdomen" @default.
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- W4384153530 doi "https://doi.org/10.3389/fnetp.2023.1205476" @default.
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