Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384154414> ?p ?o ?g. }
- W4384154414 abstract "The goal of this pilot MRI study was to understand how focal transcranial direct current stimulation (tDCS) targeting auditory cortex changes brain function in chronic tinnitus.People with chronic tinnitus were randomized to active or sham tDCS on five consecutive days in this pilot mechanistic trial (n=10/group). Focal 4×1 tDCS (central anode, surround cathodes) targeted left auditory cortex, with single-blind 2mA current during twenty-minute sessions. Arterial spin-labeled and blood oxygenation level dependent MRI occurred immediately before and after the first tDCS session, and tinnitus symptoms were measured starting one week before the first tDCS session and through four weeks after the final session.Acute increases in cerebral blood flow and functional connectivity were noted in auditory cortex after the first active tDCS session. Reduced tinnitus loudness ratings after the final tDCS session correlated with acute change in functional connectivity between an auditory network and mediodorsal thalamus and prefrontal cortex. Reduced tinnitus intrusiveness also correlated with acute change in connectivity between precuneus and an auditory network.Focal auditory-cortex tDCS can influence function in thalamus, auditory, and prefrontal cortex, which may associate with improved tinnitus.With future refinement, noninvasive brain stimulation targeting auditory cortex could become a viable intervention for tinnitus.Focal transcranial direct current stimulation (tDCS) of auditory cortex changes cerebral blood flow and connectivity in tinnitusTinnitus loudness ratings decreased on average after five sessions of active focal tDCSAcute changes in auditory, thalamic, and prefrontal function may predict quieter tinnitus after five sessions." @default.
- W4384154414 created "2023-07-14" @default.
- W4384154414 creator A5046245656 @default.
- W4384154414 creator A5076169239 @default.
- W4384154414 creator A5087847750 @default.
- W4384154414 date "2023-07-13" @default.
- W4384154414 modified "2023-10-05" @default.
- W4384154414 title "Focal transcranial direct current stimulation of auditory cortex in chronic tinnitus: A randomized controlled mechanistic trial" @default.
- W4384154414 cites W1541480878 @default.
- W4384154414 cites W1553676890 @default.
- W4384154414 cites W1827514260 @default.
- W4384154414 cites W1849616893 @default.
- W4384154414 cites W1894910337 @default.
- W4384154414 cites W1928978797 @default.
- W4384154414 cites W1949564295 @default.
- W4384154414 cites W1951724000 @default.
- W4384154414 cites W1951885772 @default.
- W4384154414 cites W1968273070 @default.
- W4384154414 cites W1968713899 @default.
- W4384154414 cites W1978441796 @default.
- W4384154414 cites W1980798536 @default.
- W4384154414 cites W1988156022 @default.
- W4384154414 cites W1988218008 @default.
- W4384154414 cites W1992009432 @default.
- W4384154414 cites W1995774446 @default.
- W4384154414 cites W2001182593 @default.
- W4384154414 cites W2003052230 @default.
- W4384154414 cites W2011241648 @default.
- W4384154414 cites W2013772387 @default.
- W4384154414 cites W2016741875 @default.
- W4384154414 cites W2018972291 @default.
- W4384154414 cites W2020044743 @default.
- W4384154414 cites W2034646869 @default.
- W4384154414 cites W2055764091 @default.
- W4384154414 cites W2060616948 @default.
- W4384154414 cites W2061085766 @default.
- W4384154414 cites W2062103870 @default.
- W4384154414 cites W2067456724 @default.
- W4384154414 cites W2072941199 @default.
- W4384154414 cites W2077427534 @default.
- W4384154414 cites W2079890482 @default.
- W4384154414 cites W2079950626 @default.
- W4384154414 cites W2086557705 @default.
- W4384154414 cites W2086815961 @default.
- W4384154414 cites W2089656517 @default.
- W4384154414 cites W2097273459 @default.
- W4384154414 cites W2104466105 @default.
- W4384154414 cites W2105558714 @default.
- W4384154414 cites W2108188136 @default.
- W4384154414 cites W2113129909 @default.
- W4384154414 cites W2115504852 @default.
- W4384154414 cites W2116136260 @default.
- W4384154414 cites W2116641010 @default.
- W4384154414 cites W2126844719 @default.
- W4384154414 cites W2129212500 @default.
- W4384154414 cites W2137445530 @default.
- W4384154414 cites W2142213531 @default.
- W4384154414 cites W2142324521 @default.
- W4384154414 cites W2142709786 @default.
- W4384154414 cites W2144958723 @default.
- W4384154414 cites W2147546041 @default.
- W4384154414 cites W2153990530 @default.
- W4384154414 cites W2155105573 @default.
- W4384154414 cites W2156727119 @default.
- W4384154414 cites W2157446241 @default.
- W4384154414 cites W2158327608 @default.
- W4384154414 cites W2160906049 @default.
- W4384154414 cites W2167234030 @default.
- W4384154414 cites W2168518533 @default.
- W4384154414 cites W2177673348 @default.
- W4384154414 cites W2252713678 @default.
- W4384154414 cites W2300876890 @default.
- W4384154414 cites W2336600599 @default.
- W4384154414 cites W2342577938 @default.
- W4384154414 cites W2415005901 @default.
- W4384154414 cites W2425755063 @default.
- W4384154414 cites W2557141979 @default.
- W4384154414 cites W2567460568 @default.
- W4384154414 cites W2593796352 @default.
- W4384154414 cites W2611373719 @default.
- W4384154414 cites W2732204853 @default.
- W4384154414 cites W2743133066 @default.
- W4384154414 cites W2765509638 @default.
- W4384154414 cites W2782874078 @default.
- W4384154414 cites W2791131719 @default.
- W4384154414 cites W2884356941 @default.
- W4384154414 cites W2884366179 @default.
- W4384154414 cites W2890269627 @default.
- W4384154414 cites W2946010820 @default.
- W4384154414 cites W2951617899 @default.
- W4384154414 cites W2963410151 @default.
- W4384154414 cites W2969911489 @default.
- W4384154414 cites W3034822760 @default.
- W4384154414 cites W3087546768 @default.
- W4384154414 cites W3108825641 @default.
- W4384154414 cites W3133504963 @default.
- W4384154414 cites W3159432451 @default.
- W4384154414 cites W3178750140 @default.
- W4384154414 cites W3197696608 @default.
- W4384154414 cites W3203642959 @default.