Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384155196> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4384155196 abstract "Abstract Purpose Parathyroid allotransplantation is an alternative therapy for refractory permanent hypoparathyroidism (PH). Herein, we present the cases of two women who developed severe PH after neck surgery for papillary thyroid cancer and underwent parathyroid allotransplantation. Despite taking high doses of calcium and calcitriol supplements, the patients experienced persistent and severe hypocalcemic symptoms. Methods Fresh parathyroid tissue was removed and prepared from two patients with hyperparathyroidism secondary to end-stage kidney disease, and implanted in the non-dominant forearm of the recipients. Donors and recipients were ABO-compatible, and immunological screening was performed only in Case 2 (HLA typing, Panel Reactive Antibody, and crossmatch tests). A short-term immunosuppressive regimen was adopted, which consists of three days of methylprednisolone followed by seven days of prednisone. Results In Case 1, oral supplementation decreased to half of the initial dose one month after transplantation and to one-fifth at the end of a 12-month follow-up period. In Case 2, intravenous calcium could be discontinued one week post-transplantation, and it was not required until six months after transplantation. Serum parathyroid hormone levels did not increase and remained mostly undetectable in both cases. In contrast, serum calcium levels increased significantly, and both patients experienced relief from hypocalcemic symptoms. Conclusion Parathyroid allotransplantation can be an effective and safe treatment for permanent PH, and should be considered in severe cases. Nevertheless, formal recommendations depend on additional studies and validated protocols." @default.
- W4384155196 created "2023-07-14" @default.
- W4384155196 creator A5010491124 @default.
- W4384155196 creator A5023493862 @default.
- W4384155196 creator A5034069058 @default.
- W4384155196 creator A5080689145 @default.
- W4384155196 creator A5090672302 @default.
- W4384155196 date "2023-07-13" @default.
- W4384155196 modified "2023-09-25" @default.
- W4384155196 title "Parathyroid allotransplantation for severe post-surgical hypoparathyroidism: a Brazilian experience" @default.
- W4384155196 cites W1586269829 @default.
- W4384155196 cites W1977441407 @default.
- W4384155196 cites W2004836582 @default.
- W4384155196 cites W2070641122 @default.
- W4384155196 cites W2072220728 @default.
- W4384155196 cites W2082321716 @default.
- W4384155196 cites W2101680622 @default.
- W4384155196 cites W2123175104 @default.
- W4384155196 cites W2140378010 @default.
- W4384155196 cites W2146195922 @default.
- W4384155196 cites W2179017712 @default.
- W4384155196 cites W2290759854 @default.
- W4384155196 cites W2310601435 @default.
- W4384155196 cites W2324932423 @default.
- W4384155196 cites W2344028044 @default.
- W4384155196 cites W2396153652 @default.
- W4384155196 cites W2503308926 @default.
- W4384155196 cites W2531651190 @default.
- W4384155196 cites W2626165570 @default.
- W4384155196 cites W2743052525 @default.
- W4384155196 cites W2914654038 @default.
- W4384155196 cites W2941528831 @default.
- W4384155196 cites W2950268294 @default.
- W4384155196 cites W2964409692 @default.
- W4384155196 cites W3117144176 @default.
- W4384155196 cites W3187660342 @default.
- W4384155196 cites W4205565604 @default.
- W4384155196 cites W4226457887 @default.
- W4384155196 cites W4230414410 @default.
- W4384155196 cites W4231900100 @default.
- W4384155196 cites W4241879662 @default.
- W4384155196 doi "https://doi.org/10.21203/rs.3.rs-3104882/v1" @default.
- W4384155196 hasPublicationYear "2023" @default.
- W4384155196 type Work @default.
- W4384155196 citedByCount "0" @default.
- W4384155196 crossrefType "posted-content" @default.
- W4384155196 hasAuthorship W4384155196A5010491124 @default.
- W4384155196 hasAuthorship W4384155196A5023493862 @default.
- W4384155196 hasAuthorship W4384155196A5034069058 @default.
- W4384155196 hasAuthorship W4384155196A5080689145 @default.
- W4384155196 hasAuthorship W4384155196A5090672302 @default.
- W4384155196 hasBestOaLocation W43841551961 @default.
- W4384155196 hasConcept C126322002 @default.
- W4384155196 hasConcept C126894567 @default.
- W4384155196 hasConcept C141071460 @default.
- W4384155196 hasConcept C2775941721 @default.
- W4384155196 hasConcept C2776541429 @default.
- W4384155196 hasConcept C2776886416 @default.
- W4384155196 hasConcept C2777561873 @default.
- W4384155196 hasConcept C2779126354 @default.
- W4384155196 hasConcept C2780252810 @default.
- W4384155196 hasConcept C2781208988 @default.
- W4384155196 hasConcept C2911091166 @default.
- W4384155196 hasConcept C519063684 @default.
- W4384155196 hasConcept C71924100 @default.
- W4384155196 hasConcept C90924648 @default.
- W4384155196 hasConceptScore W4384155196C126322002 @default.
- W4384155196 hasConceptScore W4384155196C126894567 @default.
- W4384155196 hasConceptScore W4384155196C141071460 @default.
- W4384155196 hasConceptScore W4384155196C2775941721 @default.
- W4384155196 hasConceptScore W4384155196C2776541429 @default.
- W4384155196 hasConceptScore W4384155196C2776886416 @default.
- W4384155196 hasConceptScore W4384155196C2777561873 @default.
- W4384155196 hasConceptScore W4384155196C2779126354 @default.
- W4384155196 hasConceptScore W4384155196C2780252810 @default.
- W4384155196 hasConceptScore W4384155196C2781208988 @default.
- W4384155196 hasConceptScore W4384155196C2911091166 @default.
- W4384155196 hasConceptScore W4384155196C519063684 @default.
- W4384155196 hasConceptScore W4384155196C71924100 @default.
- W4384155196 hasConceptScore W4384155196C90924648 @default.
- W4384155196 hasLocation W43841551961 @default.
- W4384155196 hasOpenAccess W4384155196 @default.
- W4384155196 hasPrimaryLocation W43841551961 @default.
- W4384155196 hasRelatedWork W2045244606 @default.
- W4384155196 hasRelatedWork W2084272222 @default.
- W4384155196 hasRelatedWork W2271190090 @default.
- W4384155196 hasRelatedWork W2348707277 @default.
- W4384155196 hasRelatedWork W2358939561 @default.
- W4384155196 hasRelatedWork W2507361224 @default.
- W4384155196 hasRelatedWork W2743052525 @default.
- W4384155196 hasRelatedWork W2921419306 @default.
- W4384155196 hasRelatedWork W3139574841 @default.
- W4384155196 hasRelatedWork W4200049415 @default.
- W4384155196 isParatext "false" @default.
- W4384155196 isRetracted "false" @default.
- W4384155196 workType "article" @default.