FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384157030> ?p ?o ?g. }

• W4384157030 endingPage "e18287" @default.
• W4384157030 startingPage "e18287" @default.
• W4384157030 abstract "Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder that progressively leads to motor neuron degeneration at the neuromuscular junctions, resulting in paralysis in the patients. The clinical diagnosis of ALS is time taking and further delays the therapeutics that can be helpful if the disease is diagnosed at an early stage. Changes in plasma composition can be reflected upon CSF composition and hence, can be used to study the diagnosis and prognosis markers for the disease.To develop a simple model system using motor neuron like cell line after plasma induction.Neuroblastoma × Spinal Cord hybridoma cell line (NSC34) was cultured under appropriate conditions. 10% ALS patients' plasma was added to the media, and cells were conditioned for 12 h. Cell survival analysis and differential gene expression of a panel of molecules (published previously, VEGF, VEGFR2, ANG, OPTN, TDP43, and MCP-1) were done.ALS patients' plasma impacted the life of the cells and reduced survival to nearly 50% after induction. VEGF was found to be significantly down-regulated in the cells, which can be explained as a reason for reduced cell survival.ALS plasma altered the expression of an essential neuroprotective and growth factor VEGF in NSC34 cells leading to reduced viability." @default.
• W4384157030 created "2023-07-14" @default.
• W4384157030 creator A5071556666 @default.
• W4384157030 creator A5081130011 @default.
• W4384157030 creator A5088498181 @default.
• W4384157030 creator A5091337350 @default.
• W4384157030 date "2023-07-01" @default.
• W4384157030 modified "2023-09-28" @default.
• W4384157030 title "ALS plasma reduces the viability of NSC34 cells via altering mRNA expression of VEGF: A short report" @default.
• W4384157030 cites W1967818741 @default.
• W4384157030 cites W1968794985 @default.
• W4384157030 cites W1972539656 @default.
• W4384157030 cites W1972681625 @default.
• W4384157030 cites W1982605324 @default.
• W4384157030 cites W1983664559 @default.
• W4384157030 cites W2010233410 @default.
• W4384157030 cites W2021359548 @default.
• W4384157030 cites W2027720028 @default.
• W4384157030 cites W2038496797 @default.
• W4384157030 cites W2040891140 @default.
• W4384157030 cites W2063183749 @default.
• W4384157030 cites W2066828509 @default.
• W4384157030 cites W2078553419 @default.
• W4384157030 cites W2136160849 @default.
• W4384157030 cites W2146753595 @default.
• W4384157030 cites W2153504354 @default.
• W4384157030 cites W2308131719 @default.
• W4384157030 cites W2518903135 @default.
• W4384157030 cites W2561467060 @default.
• W4384157030 cites W2585153753 @default.
• W4384157030 cites W2867038489 @default.
• W4384157030 cites W2887102673 @default.
• W4384157030 cites W2915252205 @default.
• W4384157030 cites W2920976911 @default.
• W4384157030 cites W2946669328 @default.
• W4384157030 cites W2949412944 @default.
• W4384157030 cites W2979488415 @default.
• W4384157030 cites W3020857036 @default.
• W4384157030 cites W3044951224 @default.
• W4384157030 cites W3047926658 @default.
• W4384157030 cites W3080922647 @default.
• W4384157030 cites W3129289712 @default.
• W4384157030 doi "https://doi.org/10.1016/j.heliyon.2023.e18287" @default.
• W4384157030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37519724" @default.
• W4384157030 hasPublicationYear "2023" @default.
• W4384157030 type Work @default.
• W4384157030 citedByCount "0" @default.
• W4384157030 crossrefType "journal-article" @default.
• W4384157030 hasAuthorship W4384157030A5071556666 @default.
• W4384157030 hasAuthorship W4384157030A5081130011 @default.
• W4384157030 hasAuthorship W4384157030A5088498181 @default.
• W4384157030 hasAuthorship W4384157030A5091337350 @default.
• W4384157030 hasBestOaLocation W43841570301 @default.
• W4384157030 hasConcept C142724271 @default.
• W4384157030 hasConcept C1491633281 @default.
• W4384157030 hasConcept C153911025 @default.
• W4384157030 hasConcept C167734588 @default.
• W4384157030 hasConcept C169760540 @default.
• W4384157030 hasConcept C185592680 @default.
• W4384157030 hasConcept C25498285 @default.
• W4384157030 hasConcept C2776715637 @default.
• W4384157030 hasConcept C2776752467 @default.
• W4384157030 hasConcept C2777025900 @default.
• W4384157030 hasConcept C2779134260 @default.
• W4384157030 hasConcept C2780596555 @default.
• W4384157030 hasConcept C2780775167 @default.
• W4384157030 hasConcept C502942594 @default.
• W4384157030 hasConcept C53227056 @default.
• W4384157030 hasConcept C54355233 @default.
• W4384157030 hasConcept C55493867 @default.
• W4384157030 hasConcept C71924100 @default.
• W4384157030 hasConcept C81885089 @default.
• W4384157030 hasConcept C86803240 @default.
• W4384157030 hasConceptScore W4384157030C142724271 @default.
• W4384157030 hasConceptScore W4384157030C1491633281 @default.
• W4384157030 hasConceptScore W4384157030C153911025 @default.
• W4384157030 hasConceptScore W4384157030C167734588 @default.
• W4384157030 hasConceptScore W4384157030C169760540 @default.
• W4384157030 hasConceptScore W4384157030C185592680 @default.
• W4384157030 hasConceptScore W4384157030C25498285 @default.
• W4384157030 hasConceptScore W4384157030C2776715637 @default.
• W4384157030 hasConceptScore W4384157030C2776752467 @default.
• W4384157030 hasConceptScore W4384157030C2777025900 @default.
• W4384157030 hasConceptScore W4384157030C2779134260 @default.
• W4384157030 hasConceptScore W4384157030C2780596555 @default.
• W4384157030 hasConceptScore W4384157030C2780775167 @default.
• W4384157030 hasConceptScore W4384157030C502942594 @default.
• W4384157030 hasConceptScore W4384157030C53227056 @default.
• W4384157030 hasConceptScore W4384157030C54355233 @default.
• W4384157030 hasConceptScore W4384157030C55493867 @default.
• W4384157030 hasConceptScore W4384157030C71924100 @default.
• W4384157030 hasConceptScore W4384157030C81885089 @default.
• W4384157030 hasConceptScore W4384157030C86803240 @default.
• W4384157030 hasIssue "7" @default.
• W4384157030 hasLocation W43841570301 @default.
• W4384157030 hasLocation W43841570302 @default.
• W4384157030 hasLocation W43841570303 @default.
• W4384157030 hasOpenAccess W4384157030 @default.

• next