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• W4384199775 abstract "Abstract Second near-infrared (NIR-II) fluorescence imaging in the range of 1000–1700 nm has great prospects for in vivo imaging and theranostics monitoring. At present, few NIR-II probes with theranostics properties have been developed, especially the high-performance organic theranostics material remains underexploited. Herein, we demonstrate a selenium-tailoring method to develop high-efficient NIR-II imaging-guided material for in vivo cancer phototheranostics. Via selenium (Se)-tailoring strategy, conjugated oligomer TPSe-based nanoparticles (NPs) achieve bright NIR-II emission up to 1400 nm and exhibit a relatively high photothermal conversion efficiency of 60% with good stability. Moreover, the TPSe NPs demonstrate their photothermal ablation of cancer cells in vitro and tumor in vivo with the guidance of NIR-II imaging. It is worth noting that the TPSe NPs have good biocompatibility without obvious side effects. Thus, this work provides new insight into the development of NIR-II theranostics agents." @default.
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• W4384199775 date "2023-07-13" @default.
• W4384199775 modified "2023-10-16" @default.
• W4384199775 title "Selenium-Integrated Conjugated Oligomer Nanoparticles with High Photothermal Conversion Efficiency for NIR-II Imaging-Guided Cancer Phototheranostics In Vivo" @default.
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• W4384199775 doi "https://doi.org/10.21203/rs.3.rs-3149294/v1" @default.
• W4384199775 hasPublicationYear "2023" @default.
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