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- W4384200220 abstract "Abstract Triadimefon, a type of triazole systemic fungicide, has been extensively used to control various fungal diseases. However, extensive application of triadimefon contributes to austere environmental pollution, and even threatens human health. In our study, Enterobacter hormaechei strain TY18 could grew well in carbon salt medium (CSM) with triadimefon as sole nitrogen source, and could significantlydegrade triadimefon. Under triadimefon stress, a total of 430 differentially expressed genes (DEGs), including 197 up-regulated and 233 down-regulated DEGs, were found in strain TY18 from transcriptome sequencing (RNA-Seq). Functional classification and enrichment analysis revealed that these DEGs were mainly related to amino acid transport and metabolism, carbohydrate transport and metabolism, small molecule and pyrimidine metabolism. Interestingly, the DEGs encoding monooxygenase and hydrolase activity acting on carbon-nitrogen were highly up-regulated, might be mainly responsible for the metabolism in triadimefon. The finding in this work suggested that the novel strain E. hormaechei TY18 could degrade efficiently triadimefon for the first time, and contribute to further understanding of the degradation mechanism related to triadimefon in strain TY18." @default.
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- W4384200220 date "2023-07-13" @default.
- W4384200220 modified "2023-10-17" @default.
- W4384200220 title "Characterization and transcriptome analysis of triadimefon-degrading strain Enterobacter hormaechei TY18" @default.
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- W4384200220 doi "https://doi.org/10.21203/rs.3.rs-3140996/v1" @default.
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