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• W4384200746 abstract "Abstract Introduction: Schistosomiasis affects approximately 230 million people worldwide. With the rise of international travel and immigration from endemic areas, there is an increase incidence of imported urinary schistosomiasis cases in France witch raise the risk of indigenous cases as observed in Corsica. European pediatricians are not used to this pathology. The objective of this study is to provide a better description of the clinical and paraclinical characteristics and the evolution of affected children. Material and methods: We contacted all French pediatric centers that may have treated children with urinary schistosomiasis, between 2013 and 2019, through the French pediatric nephrology society and the pediatric infectious pathology group. Age, sex, comorbidities, initial and follow-up clinical, biological and radiological characteristics were collected retrospectively. Results: A total of 122 patients from 10 different centers were included. The median age was 14 years and the sex ratio M/F was 4:1. Hematuria was present in 82% of the patients while urinary tract abnormality were found in 36% of them. 14 patients (11%) presented with complicated form of urinary schistosomiasis including 10 patients with renal failure. All patients received treatment with praziquantel, which was well tolerated and led to clinical resolution of the disease in 98% of cases. Conclusion: The diagnosis, management and follow-up of genital schistosomiasis must be improved, particularly by implementing systematic screening of patients returning from endemic areas, conducting renal ultrasounds and searching for nephrological complications such as renal failure and persistent proteinuria. A prospective study to evaluate long-term complications is essential." @default.
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• W4384200746 date "2023-07-13" @default.
• W4384200746 modified "2023-10-17" @default.
• W4384200746 title "Pediatric urogenital schistosomiasis diagnosed in France" @default.
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• W4384200746 doi "https://doi.org/10.21203/rs.3.rs-3149370/v1" @default.
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