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- W4384201504 abstract "Objective: The chronic autoimmune disease affecting the joints that are characterized by a progressive symmetric inflammation of affected joints resulting in cartilage destruction, bone erosion, and disability has been called Rheumatoid arthritis (RA). The aim of this study is to the assessment of FAS and lipid profiles in Iraqi patients with RA. Methods: In the current study, the demographic characteristics of the 90 studied subjects, 45 patients with RA, and 45 control subjects. Results: The result showed statically significance for increased cholesterol, and LDL in the study group (p-value<0.0001,<0.001 respectively ), while HDL was found to be significant decrease (p-value< 0.001) and non-significant for TG, VLDL (p-value 0.1,0.09 respectively). The current study concludes that there is a significant difference in the level of the fatty acid synthase FAS enzyme between the patients (0.93 ± 0.53) and control group (0.74 ± 0.45), p-value (0.001) where the patients group has a higher level of the fatty acid synthase than the control group. This study conducted that there is a significant difference in the level of the IL-17A levels (pg/ml) between the patients (166 ± 13) and control group (87 ± 5), p-value (0.001) where the patients group has a higher level of the IL-17A than the control group. Conclusion: Assessment of both FAS and IL-17A may be given as an appropriate and useful method for diagnosis and following with patients with RA." @default.
- W4384201504 created "2023-07-14" @default.
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- W4384201504 date "2023-07-05" @default.
- W4384201504 modified "2023-09-30" @default.
- W4384201504 title "The Physiological Role of FAS and IL-17A as a Markers in the Diagnosis of Rheumatoid Arthritis" @default.
- W4384201504 doi "https://doi.org/10.47191/ijpbms/v3-i7-01" @default.
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