Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384206961> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4384206961 abstract "Previous studies have reported a higher prevalence of triple-negative breast cancer (TNBC) in US Hispanic/Latina populations. However, survival outcomes and treatment approaches over time in Latin American females are scarcely reported. We aimed to evaluate the temporal variation in treatment patterns and overall survival (OS) outcomes of females with TNBC according to cancer stage.We performed a single-center retrospective cohort study on 1840 females from 2000 to 2014. Patients were classified in 3 calendar periods (2000-2004, 2005-2009, and 2010-2014). The Kaplan-Meier method and multivariable regression analyses were employed.Stage III cancer was identified in half of the population. Five-year OS estimates for cancer stages I, II, and IV remained unchanged across all calendar periods. However, we found worsening 5-year OS estimates in stage III females (49% in 2000-2004 and 31% in 2010-2014; P < .001). Despite increased uptake of overall use of neoadjuvant therapy in stage III females, the time from diagnosis to treatment initiation (P = .013) and time to complete the planned cycles (P < .001) increased over time. Fifty-sex percent of stage IV patients were untreated. Females aged ≥70 years were less likely to receive treatment.Survival estimates were lower than those reported in high-income countries. Most females were diagnosed with advanced disease, and the OS for stage III females worsened over time. Our outcomes show difficulties in delivering timely neoadjuvant therapy in an overwhelmed healthcare system. Public health authorities should improve screening practices, develop regional clinical guidelines, and expand trial enrollment." @default.
- W4384206961 created "2023-07-14" @default.
- W4384206961 creator A5019516323 @default.
- W4384206961 creator A5033649018 @default.
- W4384206961 creator A5043643636 @default.
- W4384206961 creator A5056734221 @default.
- W4384206961 creator A5087782916 @default.
- W4384206961 date "2023-07-01" @default.
- W4384206961 modified "2023-10-03" @default.
- W4384206961 title "Temporal variation of treatment patterns and survival outcomes of triple-negative breast cancer patients: A real-world experience from 2000 to 2014" @default.
- W4384206961 cites W1931022673 @default.
- W4384206961 cites W2089041626 @default.
- W4384206961 cites W2102717344 @default.
- W4384206961 cites W2112657305 @default.
- W4384206961 cites W2118605519 @default.
- W4384206961 cites W2134231081 @default.
- W4384206961 cites W2147415463 @default.
- W4384206961 cites W2159427817 @default.
- W4384206961 cites W2166085636 @default.
- W4384206961 cites W2554176272 @default.
- W4384206961 cites W2612233476 @default.
- W4384206961 cites W2756932793 @default.
- W4384206961 cites W2783881873 @default.
- W4384206961 cites W2787553551 @default.
- W4384206961 cites W2795120383 @default.
- W4384206961 cites W2889646458 @default.
- W4384206961 cites W2904537972 @default.
- W4384206961 cites W2912529815 @default.
- W4384206961 cites W2959687156 @default.
- W4384206961 cites W3080376154 @default.
- W4384206961 cites W3081189407 @default.
- W4384206961 cites W3083487657 @default.
- W4384206961 cites W3087025410 @default.
- W4384206961 cites W3093075280 @default.
- W4384206961 cites W3109589872 @default.
- W4384206961 cites W3109830226 @default.
- W4384206961 cites W3128646645 @default.
- W4384206961 doi "https://doi.org/10.1016/j.clbc.2023.07.003" @default.
- W4384206961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37507258" @default.
- W4384206961 hasPublicationYear "2023" @default.
- W4384206961 type Work @default.
- W4384206961 citedByCount "0" @default.
- W4384206961 crossrefType "journal-article" @default.
- W4384206961 hasAuthorship W4384206961A5019516323 @default.
- W4384206961 hasAuthorship W4384206961A5033649018 @default.
- W4384206961 hasAuthorship W4384206961A5043643636 @default.
- W4384206961 hasAuthorship W4384206961A5056734221 @default.
- W4384206961 hasAuthorship W4384206961A5087782916 @default.
- W4384206961 hasConcept C121608353 @default.
- W4384206961 hasConcept C126322002 @default.
- W4384206961 hasConcept C143998085 @default.
- W4384206961 hasConcept C144024400 @default.
- W4384206961 hasConcept C146357865 @default.
- W4384206961 hasConcept C149923435 @default.
- W4384206961 hasConcept C151730666 @default.
- W4384206961 hasConcept C167135981 @default.
- W4384206961 hasConcept C2778292576 @default.
- W4384206961 hasConcept C2780110267 @default.
- W4384206961 hasConcept C2908647359 @default.
- W4384206961 hasConcept C530470458 @default.
- W4384206961 hasConcept C71924100 @default.
- W4384206961 hasConcept C72563966 @default.
- W4384206961 hasConcept C86803240 @default.
- W4384206961 hasConcept C99454951 @default.
- W4384206961 hasConceptScore W4384206961C121608353 @default.
- W4384206961 hasConceptScore W4384206961C126322002 @default.
- W4384206961 hasConceptScore W4384206961C143998085 @default.
- W4384206961 hasConceptScore W4384206961C144024400 @default.
- W4384206961 hasConceptScore W4384206961C146357865 @default.
- W4384206961 hasConceptScore W4384206961C149923435 @default.
- W4384206961 hasConceptScore W4384206961C151730666 @default.
- W4384206961 hasConceptScore W4384206961C167135981 @default.
- W4384206961 hasConceptScore W4384206961C2778292576 @default.
- W4384206961 hasConceptScore W4384206961C2780110267 @default.
- W4384206961 hasConceptScore W4384206961C2908647359 @default.
- W4384206961 hasConceptScore W4384206961C530470458 @default.
- W4384206961 hasConceptScore W4384206961C71924100 @default.
- W4384206961 hasConceptScore W4384206961C72563966 @default.
- W4384206961 hasConceptScore W4384206961C86803240 @default.
- W4384206961 hasConceptScore W4384206961C99454951 @default.
- W4384206961 hasLocation W43842069611 @default.
- W4384206961 hasLocation W43842069612 @default.
- W4384206961 hasOpenAccess W4384206961 @default.
- W4384206961 hasPrimaryLocation W43842069611 @default.
- W4384206961 hasRelatedWork W1999292713 @default.
- W4384206961 hasRelatedWork W2139975046 @default.
- W4384206961 hasRelatedWork W2263577673 @default.
- W4384206961 hasRelatedWork W2317787856 @default.
- W4384206961 hasRelatedWork W2331329572 @default.
- W4384206961 hasRelatedWork W2338954311 @default.
- W4384206961 hasRelatedWork W2376078656 @default.
- W4384206961 hasRelatedWork W2554176272 @default.
- W4384206961 hasRelatedWork W3044626609 @default.
- W4384206961 hasRelatedWork W3186761709 @default.
- W4384206961 isParatext "false" @default.
- W4384206961 isRetracted "false" @default.
- W4384206961 workType "article" @default.