FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384207802> ?p ?o ?g. }

• W4384207802 endingPage "65" @default.
• W4384207802 startingPage "59" @default.
• W4384207802 abstract "Anthracycline-based chemotherapy has improved the prognosis of various malignancies, but increases the long-term risk of heart failure (HF). Identification of patients at risk prior to treatment initiation is warranted. Therefore, the aim of this study was to evaluate if a familial predisposition to HF increases the risk of anthracycline related HF. Using nationwide Danish registries, all patients treated with anthracycline from 2004-16 were identified. The primary outcome was long-term HF risk. First-degree relatives were identified in the Danish Family Registry and exposure was defined as a first-degree biological relative with prior HF. Risk of HF was evaluated in a cumulative incidence function and the association in a multivariable Cox regression model. A total of 11,651 patients (median age 49.1 years (IQR: 43.6–53.7), 12.2% male) were included after exclusion of 46 with pre-anthracycline HF. Median follow-up was 3.8 years (IQR 1.9-6.4). In the group with a first-degree relative with HF (n=1,608) 35 patients (2.2%) were diagnosed with HF vs. 133 (1.3%) in the group without a first-degree relative with HF (n=10,043), corresponding to incidence rates per 1,000 patient-years of 5.2 (CI:3.8-7.3) vs. 3.0 (CI:2.5-3.5). The cumulative incidence of HF after 10 years was higher in the first-degree relative group (3.2% vs 2.0%, p=0.004); adjusted hazard ratio 1.53 (CI:1.05-2.23, p=0.03). In this nationwide register-based study having a first-degree relative with HF was associated with increased risk of anthracycline related HF, suggesting that attention towards family predisposition may be warranted when estimating the risk of anthracycline related cardiotoxicity." @default.
• W4384207802 created "2023-07-14" @default.
• W4384207802 creator A5017241985 @default.
• W4384207802 creator A5032789207 @default.
• W4384207802 creator A5033436516 @default.
• W4384207802 creator A5033737243 @default.
• W4384207802 creator A5038410188 @default.
• W4384207802 creator A5040465744 @default.
• W4384207802 creator A5041526130 @default.
• W4384207802 creator A5057236412 @default.
• W4384207802 creator A5065895885 @default.
• W4384207802 creator A5081057548 @default.
• W4384207802 creator A5090876784 @default.
• W4384207802 date "2023-11-01" @default.
• W4384207802 modified "2023-10-13" @default.
• W4384207802 title "Importance of familial predisposition to heart failure to the risk of anthracycline-related cardiotoxicity: A nationwide study" @default.
• W4384207802 cites W1128591045 @default.
• W4384207802 cites W1828224642 @default.
• W4384207802 cites W1961026612 @default.
• W4384207802 cites W1978670003 @default.
• W4384207802 cites W1980522764 @default.
• W4384207802 cites W1988152669 @default.
• W4384207802 cites W2087912692 @default.
• W4384207802 cites W2147108549 @default.
• W4384207802 cites W2153483864 @default.
• W4384207802 cites W2219591537 @default.
• W4384207802 cites W2237393579 @default.
• W4384207802 cites W2385169442 @default.
• W4384207802 cites W2613080729 @default.
• W4384207802 cites W2725970815 @default.
• W4384207802 cites W2752560124 @default.
• W4384207802 cites W2793022017 @default.
• W4384207802 cites W2800400752 @default.
• W4384207802 cites W2804551710 @default.
• W4384207802 cites W2938273454 @default.
• W4384207802 cites W2953223155 @default.
• W4384207802 cites W3025830328 @default.
• W4384207802 cites W3041007687 @default.
• W4384207802 cites W3095452189 @default.
• W4384207802 cites W3133955595 @default.
• W4384207802 cites W3156604581 @default.
• W4384207802 doi "https://doi.org/10.1016/j.ahj.2023.07.001" @default.
• W4384207802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37453730" @default.
• W4384207802 hasPublicationYear "2023" @default.
• W4384207802 type Work @default.
• W4384207802 citedByCount "0" @default.
• W4384207802 crossrefType "journal-article" @default.
• W4384207802 hasAuthorship W4384207802A5017241985 @default.
• W4384207802 hasAuthorship W4384207802A5032789207 @default.
• W4384207802 hasAuthorship W4384207802A5033436516 @default.
• W4384207802 hasAuthorship W4384207802A5033737243 @default.
• W4384207802 hasAuthorship W4384207802A5038410188 @default.
• W4384207802 hasAuthorship W4384207802A5040465744 @default.
• W4384207802 hasAuthorship W4384207802A5041526130 @default.
• W4384207802 hasAuthorship W4384207802A5057236412 @default.
• W4384207802 hasAuthorship W4384207802A5065895885 @default.
• W4384207802 hasAuthorship W4384207802A5081057548 @default.
• W4384207802 hasAuthorship W4384207802A5090876784 @default.
• W4384207802 hasBestOaLocation W43842078021 @default.
• W4384207802 hasConcept C107130276 @default.
• W4384207802 hasConcept C120665830 @default.
• W4384207802 hasConcept C121332964 @default.
• W4384207802 hasConcept C121608353 @default.
• W4384207802 hasConcept C126322002 @default.
• W4384207802 hasConcept C151032500 @default.
• W4384207802 hasConcept C207103383 @default.
• W4384207802 hasConcept C2776694085 @default.
• W4384207802 hasConcept C2776802502 @default.
• W4384207802 hasConcept C2778198053 @default.
• W4384207802 hasConcept C2778233292 @default.
• W4384207802 hasConcept C44249647 @default.
• W4384207802 hasConcept C50382708 @default.
• W4384207802 hasConcept C530470458 @default.
• W4384207802 hasConcept C61511704 @default.
• W4384207802 hasConcept C71924100 @default.
• W4384207802 hasConcept C72563966 @default.
• W4384207802 hasConcept C82789193 @default.
• W4384207802 hasConcept C88879693 @default.
• W4384207802 hasConceptScore W4384207802C107130276 @default.
• W4384207802 hasConceptScore W4384207802C120665830 @default.
• W4384207802 hasConceptScore W4384207802C121332964 @default.
• W4384207802 hasConceptScore W4384207802C121608353 @default.
• W4384207802 hasConceptScore W4384207802C126322002 @default.
• W4384207802 hasConceptScore W4384207802C151032500 @default.
• W4384207802 hasConceptScore W4384207802C207103383 @default.
• W4384207802 hasConceptScore W4384207802C2776694085 @default.
• W4384207802 hasConceptScore W4384207802C2776802502 @default.
• W4384207802 hasConceptScore W4384207802C2778198053 @default.
• W4384207802 hasConceptScore W4384207802C2778233292 @default.
• W4384207802 hasConceptScore W4384207802C44249647 @default.
• W4384207802 hasConceptScore W4384207802C50382708 @default.
• W4384207802 hasConceptScore W4384207802C530470458 @default.
• W4384207802 hasConceptScore W4384207802C61511704 @default.
• W4384207802 hasConceptScore W4384207802C71924100 @default.
• W4384207802 hasConceptScore W4384207802C72563966 @default.
• W4384207802 hasConceptScore W4384207802C82789193 @default.
• W4384207802 hasConceptScore W4384207802C88879693 @default.
• W4384207802 hasFunder F4320322928 @default.

• next