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- W4384207821 abstract "A novel skeleton alkaloid was obtained from Portulaca oleracea L., which was identified as 10,11-dihydroxybenzo[5′,6′] pentaleno[1′,2′:3,4]pyrrolo[2,1-b]oxazol-7(11bH)-one, named oleracone M, and its structure was determined using UHPLC-ESI-QTOF/MS, 1D NMR and 2D NMR spectroscopy, and circular dichroism. Then the bioactivities of the compound were investigated including the anti-inflammatory, anti-acetylcholinesterase and antioxidant activities. The results showed that the novel skeleton alkaloid exhibited the potent effect on inhibiting the secretion of IL-1β at 10 μM, anticholinesterase activity with IC50 value of 49.58 μM, and antioxidant activity with IC50 value of 66.43 μM." @default.
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- W4384207821 date "2023-09-01" @default.
- W4384207821 modified "2023-10-18" @default.
- W4384207821 title "A novel skeleton alkaloid from Portulaca oleracea L. and its bioactivities" @default.
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- W4384207821 doi "https://doi.org/10.1016/j.fitote.2023.105608" @default.
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