FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384277130> ?p ?o ?g. }

• W4384277130 endingPage "361" @default.
• W4384277130 startingPage "355" @default.
• W4384277130 abstract "Abstract Background Bone microarchitecture is affected by multiple genes, each having a small effect on the external appearance. It is thus challenging to characterize the genes and their specific effect on bone thickness and porosity. The purpose of this study was to assess the heritability and the genetic variation effect, as well as the sex effect on the calvarial bone thickness (Ca.Th) and calvarial porosity (%PoV) using the Collaborative Cross (CC) mouse population. Methods In the study we examined the parietal bones of 56 mice from 9 lines of CC mice. Morphometric parameters were evaluated using microcomputed tomography (μCT) and included Ca.Th and %PoV. We then evaluated heritability, genetic versus environmental variance and the sex effect for these parameters. Results Our morphometric analysis showed that Ca.Th and %PoV are both significantly different among the CC lines with a broad sense heritability of 0.78 and 0.90, respectively. The sex effect within the lines was significant in line IL111 and showed higher values of Ca.Th and %PoV in females compared to males. In line IL19 there was a borderline sex effect in Ca.Th in which males showed higher values than females. Conclusions These results stress the complexity of sex and genotype interactions controlling Ca.Th and %PoV, as the skeletal sexual dimorphism was dependent on the genetic background. This study also shows that the CC population is a powerful tool for establishing the genetic effect on these traits." @default.
• W4384277130 created "2023-07-15" @default.
• W4384277130 creator A5014108462 @default.
• W4384277130 creator A5055337126 @default.
• W4384277130 creator A5059979778 @default.
• W4384277130 creator A5076143384 @default.
• W4384277130 creator A5092468459 @default.
• W4384277130 date "2023-07-13" @default.
• W4384277130 modified "2023-10-16" @default.
• W4384277130 title "A study of the influence of genetic variance and sex on the density and thickness of the calvarial bone in collaborative cross mice" @default.
• W4384277130 cites W1826010384 @default.
• W4384277130 cites W1976604752 @default.
• W4384277130 cites W1976629836 @default.
• W4384277130 cites W1981020155 @default.
• W4384277130 cites W1985033641 @default.
• W4384277130 cites W2004027999 @default.
• W4384277130 cites W2033208581 @default.
• W4384277130 cites W2051103136 @default.
• W4384277130 cites W2065766094 @default.
• W4384277130 cites W2073091851 @default.
• W4384277130 cites W2073748629 @default.
• W4384277130 cites W2074792923 @default.
• W4384277130 cites W2074959670 @default.
• W4384277130 cites W2088939501 @default.
• W4384277130 cites W2115655392 @default.
• W4384277130 cites W2120703939 @default.
• W4384277130 cites W2123989422 @default.
• W4384277130 cites W2124874293 @default.
• W4384277130 cites W2132676310 @default.
• W4384277130 cites W2138539526 @default.
• W4384277130 cites W2155286781 @default.
• W4384277130 cites W2180431768 @default.
• W4384277130 cites W2231115010 @default.
• W4384277130 cites W2275103094 @default.
• W4384277130 cites W2462469445 @default.
• W4384277130 cites W2498126750 @default.
• W4384277130 cites W2550093768 @default.
• W4384277130 cites W2586827061 @default.
• W4384277130 cites W2666508626 @default.
• W4384277130 cites W2762793015 @default.
• W4384277130 cites W2808266901 @default.
• W4384277130 cites W2967529946 @default.
• W4384277130 cites W3007932604 @default.
• W4384277130 cites W3018605863 @default.
• W4384277130 cites W3048637593 @default.
• W4384277130 cites W3167617187 @default.
• W4384277130 cites W3199406071 @default.
• W4384277130 cites W3761335 @default.
• W4384277130 cites W4297236787 @default.
• W4384277130 cites W4302767345 @default.
• W4384277130 cites W4384277130 @default.
• W4384277130 doi "https://doi.org/10.1002/ame2.12319" @default.
• W4384277130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37448168" @default.
• W4384277130 hasPublicationYear "2023" @default.
• W4384277130 type Work @default.
• W4384277130 citedByCount "1" @default.
• W4384277130 countsByYear W43842771302023 @default.
• W4384277130 crossrefType "journal-article" @default.
• W4384277130 hasAuthorship W4384277130A5014108462 @default.
• W4384277130 hasAuthorship W4384277130A5055337126 @default.
• W4384277130 hasAuthorship W4384277130A5059979778 @default.
• W4384277130 hasAuthorship W4384277130A5076143384 @default.
• W4384277130 hasAuthorship W4384277130A5092468459 @default.
• W4384277130 hasBestOaLocation W43842771301 @default.
• W4384277130 hasConcept C104317684 @default.
• W4384277130 hasConcept C105083479 @default.
• W4384277130 hasConcept C126322002 @default.
• W4384277130 hasConcept C135763542 @default.
• W4384277130 hasConcept C161890455 @default.
• W4384277130 hasConcept C2908647359 @default.
• W4384277130 hasConcept C54355233 @default.
• W4384277130 hasConcept C68873052 @default.
• W4384277130 hasConcept C70616004 @default.
• W4384277130 hasConcept C71924100 @default.
• W4384277130 hasConcept C78458016 @default.
• W4384277130 hasConcept C86803240 @default.
• W4384277130 hasConcept C90856448 @default.
• W4384277130 hasConcept C99454951 @default.
• W4384277130 hasConcept C99476002 @default.
• W4384277130 hasConceptScore W4384277130C104317684 @default.
• W4384277130 hasConceptScore W4384277130C105083479 @default.
• W4384277130 hasConceptScore W4384277130C126322002 @default.
• W4384277130 hasConceptScore W4384277130C135763542 @default.
• W4384277130 hasConceptScore W4384277130C161890455 @default.
• W4384277130 hasConceptScore W4384277130C2908647359 @default.
• W4384277130 hasConceptScore W4384277130C54355233 @default.
• W4384277130 hasConceptScore W4384277130C68873052 @default.
• W4384277130 hasConceptScore W4384277130C70616004 @default.
• W4384277130 hasConceptScore W4384277130C71924100 @default.
• W4384277130 hasConceptScore W4384277130C78458016 @default.
• W4384277130 hasConceptScore W4384277130C86803240 @default.
• W4384277130 hasConceptScore W4384277130C90856448 @default.
• W4384277130 hasConceptScore W4384277130C99454951 @default.
• W4384277130 hasConceptScore W4384277130C99476002 @default.
• W4384277130 hasFunder F4320311904 @default.
• W4384277130 hasFunder F4320322596 @default.
• W4384277130 hasIssue "4" @default.
• W4384277130 hasLocation W43842771301 @default.

• next