FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384301658> ?p ?o ?g. }

• W4384301658 abstract "Tetanus is a critical disease contracted through exposure to the spores of Clostridium tetani bacterium, which live in soil, saliva, dust, and manure. The routes of administration comprise transmission through deep open cuts, wounds, or burns affecting the nervous system. This condition is rare in developed countries. However, it remains a crucial public health issue, especially in many developing countries leading to 25,000 newborn deaths in 2018. Although, the reduction in this public health situation reached 88% compared with its situation in 20001. In Africa, tetanus is associated with increased rates of intensive care unit and hospital admissions resulting from many associated risk factors. Most importantly, the agricultural lifestyle alongside soil nature is rich in organic matter. Other factors associated with the condition were posttropical monsoon seasons, insufficiencies concerning effective wound care, and inadequate pursuit of public health awareness by governing health care authorities2,3. The best defense against tetanus is having current vaccinations. Pertussis and diphtheria are used in combination with tetanus vaccines, referred to as tetanus-toxoid-containing vaccines (TTCVs). Tetanus is a very preventable disease, with the administration of successful TTCVs used in preventing tetanus through routine immunization programes globally and provided during antenatal care4. There are currently 5 TTCVs authorized (DTaP, DTP, Tdap, Td, and DT). Diphtheria, tetanus, pertussis, and acellular are represented by the letters D, T, and P, respectively; the lowercase p and d simply indicate reduced vaccine toxoid5. DPT (diphtheria, tetanus, and pertussis) doses for children should be administered at ages 2, 4, and 6 months, with additional doses administered between ages 15 and 18 months and 4 and 6 years, according to the current Advisory Committee on Immunization Practices5. This is followed by 1 Tdap booster at 11 or 12 years, followed by a booster every decade after. Adults should receive the Td or Tdap vaccine every 10 years if all other vaccinations have been administered. One said the dose must be Tdap for individuals over the age of 19. A sequence of 3 vaccines will be administered to those who have never been immunized. The dose is administered 4 weeks after the first, and the last dose is administered 6–12 months later6. A prior illness and a vaccine’s protection do not provide lifetime protection. As a result, even if you have had tetanus or had the vaccine in the past, you still need to receive the vaccination regularly to maintain a high level of protection against this dangerous illness. However, tetanus infection can lead to serious health problems, including laryngospasm, fractures, hospital-acquired infections, pulmonary embolism, and aspiration pneumonia. Difficulties in breathing are a major cause of tetanus-associated mortality, with 1–2 in 10 cases being fatal (10%–20% of cases are fatal). Tetanus may manifest with unusual symptoms, masquerading as the underlying diagnosis. One such unusual sequelae include a case of a 20-year-old female patient who developed a series of complications post-tetanus diagnosis. These comprised locked temporomandibular joints (trismus) and fused hips bilaterally, as well as kyphoscoliosis and sustaining a right subtrochanteric fracture7. Maternal and neonatal tetanus (MNT), a neurological condition that annually threatens thousands of lives, is brought on by toxins secreted by the Clostridium tetani bacteria. WHO estimates that MNT kills 110,000 people annually in the African Region, mostly during this time of pandemic6, which accounts for 90% of all cases of neonatal tetanus worldwide. Unfortunately, the eradication of this disease is almost impossible because of the ubiquitous nature of the bacterium in the environment. Therefore, constant efforts are required to manage and maintain MNT. The level of knowledge and skills of medical practitioners correlate with the medical services provided. In this regard, little information is available concerning medical practitioners in rural Africa. But, it depends on the practitioners’ working conditions, education, training, and level of experience. A study has revealed inadequate competencies in enhancing primary health care, hospital management, and public health issues due to personnel insufficiencies, ill-developed health bodies, and lack of training8. Immunization acts as a preventative measure against pathogens9. Immunization in children is the best health care intervention and strategy to combat infectious diseases and high mortality rates among children10. In conclusion, early diagnosis and intervention are lifesaving for tetanus. Therefore, the importance of childhood immunization and boosters must be stressed. Midwives and birth attendants in African countries should receive professional training in aseptic birthing procedures. Securing appropriate routine tetanus vaccination, prophylaxis, and treatment, as well as universal coverage for developing countries, is paramount, intending to limit tetanus development and complications. Ethical approval Not Applicable. Sources of funding Not Available. Author contributions O.U., C.B., S.C.E., A.N., J.W., and M.K.S.: conceptualization of ideas, critical reviews with comments, and approved the final draft. Conflict of interest disclosures The authors declare that they have no financial conflict of interest with regards to the content of this report. Research registration unique identifying number (UIN) Not Applicable. Guarantor Abubakar Nazir." @default.
• W4384301658 created "2023-07-15" @default.
• W4384301658 creator A5001707676 @default.
• W4384301658 creator A5038973431 @default.
• W4384301658 creator A5051833019 @default.
• W4384301658 creator A5062520688 @default.
• W4384301658 creator A5079394188 @default.
• W4384301658 creator A5083668206 @default.
• W4384301658 date "2023-07-01" @default.
• W4384301658 modified "2023-10-14" @default.
• W4384301658 title "Tetanus: a terrible neurological disorder in rural Africa" @default.
• W4384301658 cites W2060915684 @default.
• W4384301658 cites W2150000849 @default.
• W4384301658 cites W2468870305 @default.
• W4384301658 cites W4292025406 @default.
• W4384301658 doi "https://doi.org/10.1097/gh9.0000000000000221" @default.
• W4384301658 hasPublicationYear "2023" @default.
• W4384301658 type Work @default.
• W4384301658 citedByCount "0" @default.
• W4384301658 crossrefType "journal-article" @default.
• W4384301658 hasAuthorship W4384301658A5001707676 @default.
• W4384301658 hasAuthorship W4384301658A5038973431 @default.
• W4384301658 hasAuthorship W4384301658A5051833019 @default.
• W4384301658 hasAuthorship W4384301658A5062520688 @default.
• W4384301658 hasAuthorship W4384301658A5079394188 @default.
• W4384301658 hasAuthorship W4384301658A5083668206 @default.
• W4384301658 hasBestOaLocation W43843016581 @default.
• W4384301658 hasConcept C138816342 @default.
• W4384301658 hasConcept C147483822 @default.
• W4384301658 hasConcept C159110408 @default.
• W4384301658 hasConcept C177713679 @default.
• W4384301658 hasConcept C187212893 @default.
• W4384301658 hasConcept C203014093 @default.
• W4384301658 hasConcept C22070199 @default.
• W4384301658 hasConcept C2777351567 @default.
• W4384301658 hasConcept C2779214499 @default.
• W4384301658 hasConcept C2779841045 @default.
• W4384301658 hasConcept C2780548902 @default.
• W4384301658 hasConcept C2780572238 @default.
• W4384301658 hasConcept C2780801004 @default.
• W4384301658 hasConcept C71924100 @default.
• W4384301658 hasConcept C99454951 @default.
• W4384301658 hasConceptScore W4384301658C138816342 @default.
• W4384301658 hasConceptScore W4384301658C147483822 @default.
• W4384301658 hasConceptScore W4384301658C159110408 @default.
• W4384301658 hasConceptScore W4384301658C177713679 @default.
• W4384301658 hasConceptScore W4384301658C187212893 @default.
• W4384301658 hasConceptScore W4384301658C203014093 @default.
• W4384301658 hasConceptScore W4384301658C22070199 @default.
• W4384301658 hasConceptScore W4384301658C2777351567 @default.
• W4384301658 hasConceptScore W4384301658C2779214499 @default.
• W4384301658 hasConceptScore W4384301658C2779841045 @default.
• W4384301658 hasConceptScore W4384301658C2780548902 @default.
• W4384301658 hasConceptScore W4384301658C2780572238 @default.
• W4384301658 hasConceptScore W4384301658C2780801004 @default.
• W4384301658 hasConceptScore W4384301658C71924100 @default.
• W4384301658 hasConceptScore W4384301658C99454951 @default.
• W4384301658 hasIssue "4" @default.
• W4384301658 hasLocation W43843016581 @default.
• W4384301658 hasOpenAccess W4384301658 @default.
• W4384301658 hasPrimaryLocation W43843016581 @default.
• W4384301658 hasRelatedWork W1985848457 @default.
• W4384301658 hasRelatedWork W1990462546 @default.
• W4384301658 hasRelatedWork W2004062023 @default.
• W4384301658 hasRelatedWork W2037799256 @default.
• W4384301658 hasRelatedWork W2356422181 @default.
• W4384301658 hasRelatedWork W2606926319 @default.
• W4384301658 hasRelatedWork W2890526154 @default.
• W4384301658 hasRelatedWork W2982212490 @default.
• W4384301658 hasRelatedWork W4212893576 @default.
• W4384301658 hasRelatedWork W4301452006 @default.
• W4384301658 hasVolume "6" @default.
• W4384301658 isParatext "false" @default.
• W4384301658 isRetracted "false" @default.
• W4384301658 workType "article" @default.